Reliability and validity study of the Migraine Interictal Burden Scale-4 in Turkish

Abstract

Objective: The objective of this study was to assess the reliability and validity of the Turkish version of the Migraine Interictal Burden Scale-4 (MIBS-4) in patients with migraine. MIBS-4 measures migraine-related interictal burden in four domains related to difficulty in planning at work or school, family and social life, and emotional/affective and cognitive stress. Materials and Methods: A total of 178 patients with migraine were enrolled in this multicenter, prospective study in two consecutive interviews with 4-week intervals. The comprehensibility, patient-physician reliability, internal consistency, test-retest reliability, and validity of the Turkish translation of MIBS-4 were analyzed. Results: In terms of comprehensibility of all MIBS-4 questions, a statistically significant agreement was obtained between the patient and the physician (intraclass correlation coefficient [ICC] = 0.713;P < 0.001, ICC = 0.851;P < 0.001, ICC = 0.637;and P < 0.001, ICC = 0.760;P < 0.001). No statistically significant difference was found between the comprehensibility of the first, second, third, and fourth questions of MIBS-4 according to the patient self-test and the physician interviews (P = 0.167, P = 0.068, P = 0.121, and P = 0.225, respectively). A significant high consistency was obtained between the first and second interview values (ICC = 0.891;P < 0.001). Cronbach's alpha coefficient was obtained between 0.818 and 0.845, and the scale was obtained with high reliability. A statistically significant positive correlation was obtained between the first and second interview MIBS values and Headache Impact Test-6, and the correlation coefficients were obtained as 0.158 and 0.330, respectively (P = 0.036 and P < 0.001, respectively). Conclusion: These results demonstrated that the Turkish translation of MIBS-4 is equivalent to the English version in terms of internal consistency, and it has high test-retest reliability and validity. The Turkish version of MIBS-4 can serve as a reliable, useful, and valid tool for assessing the burden on patients between migraine attacks, as well as aiding health-care professionals in enhancing migraine treatment strategies in Türkiye.