Department of Mechanical Engineering2024-12-2920240022-509610.1016/j.jmps.2023.1054572-s2.0-85175869299https://doi.org/10.1016/j.jmps.2023.105457https://hdl.handle.net/20.500.14288/23390We develop a simple model of ionic current through neuronal membranes as a function of membrane potential and extracellular ion concentration. The model combines a simplified Poisson-Nernst-Planck (PNP) model of ion transport through individual ion channels with channel activation functions calibrated from ad hoc in-house experimental data. The simplified PNP model is validated against bacterial gramicidin A ion channel data. The calibrated model accounts for the transport of calcium, sodium, potassium, and chloride and exhibits remarkable agreement with the experimentally measured current-voltage curves for the differentiated human neural cells.Materials scienceMultidisciplinaryMechanicsPhysicsCondensed matterJournal article1873-47821111621900001Q141533