Department of Mechanical Engineering2024-11-0920110160-564X10.1111/j.1525-1594.2010.01167.x2-s2.0-79960272635http://dx.doi.org/10.1111/j.1525-1594.2010.01167.xhttps://hdl.handle.net/20.500.14288/8686A prototype of a new implantable centrifugal blood pump system named Heart Turcica Centrifugal (HTC) was developed as a left ventricular assist device (LVAD) for the treatment of end-stage cardiac failure. In the development of HTC, effects of blade height and volute tongue profiles on the hydraulic and hemolytic performances of the pump were investigated. As a result, the prototype was manufactured using the best blade height and volute tongue profiles. Performance of the prototype model was experimentally evaluated in a closed-loop flow system using water as the medium. The hydraulic performance requirement of an LVAD (5 L/min flow rate against a pressure difference of 100 mm Hg) was attained at 2800 rpm rotational speed.EngineeringBiomedical engineeringTransplantationJournal Article2926511000141945