Department of Chemical and Biological EngineeringDepartment of Computer Engineering2024-11-0920050305-104810.1093/nar/gki5852-s2.0-23144463510https://hdl.handle.net/20.500.14288/3210Prism (https://gordion.hpc.eng.ku.edu.tr/prism) is a website for protein interface analysis and prediction of putative protein-protein interactions. It is composed of a database holding protein interface structures derived from the Protein Data Bank (PDB). The server also includes summary information about related proteins and an interactive protein interface viewer. A list of putative protein-protein interactions obtained by running our prediction algorithm can also be accessed. These results are applied to a set of protein structures obtained from the PDB at the time of algorithm execution (January 2004). Users can browse through the non-redundant dataset of representative interfaces on which the prediction algorithm depends, retrieve the list of similar structures to these interfaces or see the results of interaction predictions for a particular protein. Another service provided is interactive prediction. This is done by running the algorithm for user input structures.pdfBiochemistry and molecular biologyJournal Article1362-4962https://doi.org/10.1093/nar/gki585230271400067Q1NOIR00552