Department of Psychology2024-12-2920231090-716510.1007/s10461-023-04078-02-s2.0-85159065427https://doi.org/10.1007/s10461-023-04078-0https://hdl.handle.net/20.500.14288/23508Informed by the Health Care Empowerment Model, a measure of PrEP Empowerment was developed and assessed for preliminary reliability and validity. Participants (N = 100) were invited to complete a survey during regular clinic visits. A subset (n = 84) volunteered to provide blood samples to assess plasma tenofovir (TFV) levels for recent PrEP adherence. A five-factor measure explained 70% of the total variance. Associations with internalized PrEP stigma, PrEP adherence self-efficacy, and plasma TFV were assessed. Results supported the multidimensional nature of PrEP Empowerment and reliability and validity. Additional research is needed in populations with varying PrEP experience and greater gender and ethnic representation.PublicEnvironmentalOccupational healthSocial sciencesBiomedicalJournal article1573-3254985987500002Q241651