Department of Chemical and Biological EngineeringDepartment of Computer Engineering2024-11-0920140305-104810.1093/nar/gku3972-s2.0-84904801952https://hdl.handle.net/20.500.14288/3323The PRISM web server enables fast and accurate prediction of protein-protein interactions (PPIs). The prediction algorithm is knowledge-based. It combines structural similarity and accounts for evolutionary conservation in the template interfaces. The predicted models are stored in its repository. Given two protein structures, PRISM will provide a structural model of their complex if a matching template interface is available. Users can download the complex structure, retrieve the interface residues and visualize the complex model.pdfBiochemistry and molecular biologyJournal Article1362-4962https://doi.org/10.1093/nar/gku397339715000047Q1NOIR00551