Department of Electrical and Electronics Engineering2024-12-2920240090-677810.1109/TCOMM.2024.33765932-s2.0-85188013450https://doi.org/10.1109/TCOMM.2024.3376593https://hdl.handle.net/20.500.14288/23249Molecular Communication (MC) is a bio-inspired communication paradigm utilizing molecules for information transfer. Research on MC has largely transitioned from theoretical investigations to practical testbed implementations, harnessing microfluidics and sensor technologies. Accurate models for input-output relationships on these platforms are crucial for optimizing MC methods and understanding the impact of physical parameters on performance. Our study focuses on a practical microfluidic MC system with a graphene field effect transistor biosensor (bioFET)-based receiver, developing an end-to-end frequency-domain model. The model provides insights into the dispersion, distortion, and attenuation of received signals, thus potentially informing the design of new frequency-domain MC techniques, such as modulation and detection methods. The accuracy of the developed model is verified through particle-based spatial stochastic simulations of pulse transmission and ligand-receptor reactions on the receiver surface.Engineering, electrical and electronicTelecommunicationsJournal article1294594400042Q141392