Department of Physics2024-11-0920070378-437110.1016/j.physa.2007.07.0132-s2.0-48349129085http://dx.doi.org/10.1016/j.physa.2007.07.013https://hdl.handle.net/20.500.14288/15506We show that the out-degree distribution of the gene regulation network of the budding yeast, Saccharomyces cerevisiae, can be reproduced to high accuracy from the statistics of TF binding sequences. Our observation suggests a particular microscopic mechanism for the observed universal global topology in these networks. The numerical data and analytical solution of our model disagree with a simple power-law for the experimentally obtained degree distribution in the case of yeast.PhysicsTranscriptional regulatory network topology from statistics of DNA binding sitesConference proceeding1873-21192538434000283853