Welcome to the Koç University Institutional Academic Repository
The Koç University Institutional Academic Repository (KUHub Research) is a state-of-the-art academic repository that consolidates all academic outputs—such as articles, conference proceedings, theses, research data, and more—produced by the university since its establishment in 1993.
KUHub Research adheres to the principles of Open Access and FAIR (Findable, Accessible, Interoperable, Reusable), providing access to the bibliographic records, research data, and full texts of research outputs. Equipped with innovative features such as Author Profile pages and enhanced tools, KUHub Research aims to enhance the visibility of researchers both nationally and internationally. KUHub Research aims to preserve and maintain Koç University's valuable academic legacy for future generations while also serving the needs of today’s researchers.
For more information or inquiries please contact openaccess@ku.edu.tr
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Recent Submissions
Mechanisms of fast CO2 fixation reaction by enoyl-CoA carboxylases/reductase
(European Synchrotron Radiation Facility, 2028-01-01) Chretien, Anaïs; Ertem Kuzucu, Fatma Betul; Summers, Jacob; Wranik, Maximilian; 0000-0001-8480-1443; 0000-0002-2144-989x; 0000-0003-3113-0353; 0000-0002-2482-0164
Carbon dioxide (CO2) is an atmospheric greenhouse gas that feeds all life, plays a critical role in global warming, and could constitute an inexpensive carbon source for future sustainable industries. While synthetic chemistry lacks suitable catalysts to functionalize carbon dioxide in mild reaction conditions, autotrophs do it constantly, and thus there is increasing interest in exploiting the CO2-fixation mechanisms offered by nature. In this exchange proposal, we propose fast time-resolved structural-dynamics studies of one of the fastest CO2-fixation enzymes, enoyl-CoA carboxylase/reductase (ECR), using ambient temperature serial X-ray crystallography on Beamline ID29, ESRF, which achieves 10μs resolution. This study will reveal details of the enzyme subunit coupling as well as the enzyme-substrate interactions to correlate the structural and functional states of the enzyme during fixation and pave the way for faster biomolecule productions using engineered C-cycling enzymes.
Mechanisms of fast CO2 fixation reaction by enoyl-CoA carboxylases/reductase
(European Synchrotron Radiation Facility, 2027-01-01) Summers, Jacob; Sanctis, Daniele; Vlahakis, Niko; Knight, Victoria; Ertem Kuzucu, Fatma Betul; Chretien, Anaïs; Nurizzo, Didier; 0000-0003-3113-0353; 0000-0003-0391-8290; 0000-0002-5092-0265; 0000-0002-2144-989x; 0000-0001-8480-1443; 0000-0002-7367-5098
Carbon dioxide (CO2) is an atmospheric greenhouse gas that feeds all life, plays a critical role in global warming, and could constitute an inexpensive carbon source for future sustainable industries. While synthetic chemistry lacks suitable catalysts to functionalize carbon dioxide in mild reaction conditions, autotrophs do it constantly, and thus there is increasing interest in exploiting the CO2-fixation mechanisms offered by nature. In this exchange proposal, we propose fast time-resolved structural-dynamics studies of one of the fastest CO2-fixation enzymes, enoyl-CoA carboxylase/reductase (ECR), using ambient temperature serial X-ray crystallography on Beamline ID29, ESRF, which achieves 10μs resolution. This study will reveal details of the enzyme subunit coupling as well as the enzyme-substrate interactions to correlate the structural and functional states of the enzyme during fixation and pave the way for faster biomolecule productions using engineered C-cycling enzymes.
Through-thickness compaction response of reinforcement fabrics: Development of a test standard
(Elsevier Ltd, 2026) Master Student, Sayınbaş, Deniz; Faculty Member, Sözer, Murat; Yong, Ana X.H. (57203836326); Endruweit, Andreas (12805837100); George, Andrew R. (55813139600); May, David (57959761400); Aksoy, Y. Altay (58572894600); Ali, Muhammad Ansab (57214142353); Allen, T. D. (55778257800); Bender, Marcel (57414698300); Bodaghi, M. (55867556400); Caglar, Baris (55247112800); Caglar, Hasan (57207841000); Chiminelli, Agustίn (12780700500); Comas-Cardona, Sébastien (15753343300); de Ribains, R. (60133803000); Dittmann, Jörg (57194063754); Dransfeld, Clemens A. (8255606800); Fauster, Ewald (56257805000); Guilloux, A. (57221103098); Hubert, Pascal (55611807800); Sridhar, Idapalapati (57215553697); Ivens, Jan A. (6701470996); Janzen, Jan Philipp (58560610700); Jiang, Y. (60133965900); Khan, Tayyab (57214881556); Laspalas, Manuel (23977815400); LeBel, François (55430482800); Lee, Jeeeun (57834199900); Liu, X. (60133740300); Lizaranzu, Miguel (36859700200); Lomov, Stepan Vladimirovitch (7005067917); López, C. I. (57199822307); Masania, Kunal (23051202900); Michaud, Véronique J. (55522921700); Middendorf, Peter (24385613600); Miguel, S. (59460797700); Narayana, Sidharth Sarojini (57203062781); Park, Chung Hae (7408416878); Ravisankar Padma, Sriram (57566432200); Riffard, Lucie (6505485551); Pinger, C. (60133966000); Rougier, Valentin (57219267968); Sas, Hatice Sinem (55314958100); Sousa, Pedro (57202152216); Steinhardt, Maximilian (58127183900); Umer, Rehan (8555191500); Vincent, Jamin Daniel Selvakumar (57225093372); Werlen, Vincent (57222021128); Yuksel, Onur (56050603800); Department of Mechanical Engineering; Graduate School of Sciences and Engineering; GRADUATE SCHOOL OF SCIENCES AND ENGINEERING; College of Engineering
Characterisation of the compaction response of reinforcement fabrics is an important component in the design of composite manufacturing processes. To standardise a best practice method, 22 international organisations participated in an exercise to assess the viability and reproducibility of the method discussed in this work. All participants were supplied with the same multiaxial E-glass fibre non-crimp fabric and instructed to measure the compaction stress as a function of the specimen thickness following a set of guidelines. The scatter in results between participants was quantified in terms of the coefficient of variation (CV). The CV of the maximum compaction stress determined at a target specimen thickness of 3 mm (for 10 fabric layers) was 42 % for dry specimens and 46 % for wet specimens, however this was influenced by scatter in the thickness values, which deviated from the target. The CV of the specimen thickness at a compaction stress of 105 Pa was 4 %. In addition, a power law model and a model based on bending of beams were fitted to the compaction curves. Both generally produced fits with high values of the coefficient of determination. The observed level of scatter is thought to be caused by issues with the implementation of the procedures and by variability in the specimen properties, as well as the very steep variation of the force/thickness curve at the required target. The guidelines used here aim to minimise inaccuracies in the test method and will be proposed as a test protocol for standardisation. © 2025 Elsevier B.V., All rights reserved.
Computational investigation of deformable droplet evaporation under forced convection
(Elsevier, 2026) PhD Student, Salimnezhad, Faraz; Faculty Member, Muradoğlu, Metin; Department of Mechanical Engineering; Graduate School of Sciences and Engineering; College of Engineering; GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
Evaporation of a deformable droplet under convection is investigated and performance of the classical and Abramzon–Sirignano (A–S) models is evaluated. Using the Immersed Boundary/Front-Tracking (IB/FT) method, interface-resolved simulations are performed to examine droplet evaporation dynamics over a wide range of Reynolds (20 ≤ R e ≤ 200), Weber (0 . 65 ≤ W e ≤ 9), and mass transfer (1 ≤ B M ≤ 15) numbers. It is shown that flow in the wake region is greatly influenced by the Stefan flow as higher evaporation rates leads to an earlier flow separation and a larger recirculation zone behind the droplet. Under strong convection, the models fail to capture the evaporation rate especially in the wake region, which leads to significant discrepancies compared to interface-resolved simulations. Droplet deformation greatly influences the flow field around the droplet and generally enhances evaporation but the evaporation rate remains well correlated with the surface area. The A–S model exhibits a reasonably good performance for a nearly spherical droplet but its performance deteriorates significantly and generally underpredicts evaporation rate as droplet deformation increases. The A–S model is overall found to outperform the classical model in the presence of significant convection.
A comparative study on how academic libraries contribute to sustainability
(Emerald Publishing Limited, 2026) Other, Çanak, Tuba Akbaytürk; Cevher, Nilay; Gedik, Kübra Zayim; Bulgan, Uğur; Çimen, Ertuğrul; Sezgin, Üstün Berk; SKL (Suna Kıraç Library); Administrative Unit
Sustainability, encompassing environmental, economic, and social dimensions, is central to creating a more inhabitable future, and the United Nations (UN) Sustainable Development Goals (SDGs) address multifaceted challenges, including information access and education inequalities. Libraries, particularly academic libraries, have a core mission to provide and disseminate sustainable information, positioning them as key contributors to achieving the SDGs. This comparative study investigates the diverse roles of academic libraries in advancing these goals across Azerbaijan, Bosnia-Herzegovina, Greece, North Macedonia, and Türkiye, chosen for their regional proximity and similar socio-cultural and librarianship contexts. Drawing upon survey data, the study explores the involvement of academic libraries in sustainable development within these countries and the factors influencing their engagement. Despite a low response rate, the findings highlight a growing awareness among academic libraries and librarians toward sustainable development, revealing diverse strategies, successful approaches, and challenges encountered. Ultimately, the study underscores the vital role of academic libraries as catalysts for knowledge dissemination, community empowerment, and innovation in advancing the global sustainability agenda, offering valuable insights for policymakers and library stakeholders.