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Recent Submissions

  • Item type:Person,
    Ertrük, Ceyda
    Other
  • Item type:Person,
    Çalış, Tutku
    Master Student
  • Item type:Person,
    Karakoç, Beyza Nur
    Master Student
  • Item type:Publication,
    Y-configuration dual stent retriever thrombectomy for Bifurcation occlusions in acute ischemic stroke
    (Elsevier, 2026)
    Mücahit Karabulut, M. S.
    Bifurcation occlusions present unique technical challenges during mechanical thrombectomy. We evaluated the angiographic, clinical, and safety outcomes of Y-configuration dual stent retriever thrombectomy in patients with acute ischemic stroke caused by bifurcation occlusions. Methods We retrospectively analyzed 32 consecutive patients treated with Y-configuration dual stent retriever thrombectomy between April 2018 and January 2025. The technique was used as a rescue strategy after failed single-device attempts or as a first-line approach in selected bifurcation occlusions. Angiographic outcomes, procedural metrics, complications, and 90-day clinical outcomes were assessed. Results The middle cerebral artery was the most common occlusion site (81.3%). Successful reperfusion (TICI ≥2b) was achieved in 97% of patients, with complete reperfusion (TICI 3) in 91% of cases. Following the first Y-configuration thrombectomy attempt, successful reperfusion (TICI ≥2b) was achieved in 87% of cases, irrespective of prior thrombectomy attempts. Median NIHSS improved from 16 at baseline to 7 at 24 hours. At 90 days, 53% of patients achieved functional independence (mRS ≤2). Symptomatic intracranial hemorrhage occurred in 6.3%; any intracranial hemorrhage occurred in 9.4%, and no vasospasm, vessel dissection, device-related perforation, or subarachnoid hemorrhage was observed. Conclusions Y-configuration dual stent retriever thrombectomy appears feasible as a rescue option for selected complex bifurcation occlusions refractory to conventional thrombectomy. Prospective comparative studies are needed to further establish its safety, efficacy, and optimal indications.
  • Item type:Publication,
    The role of urodynamics in overactive bladder: a critical in-depth analysis of the FUTURE study
    (Springer, 2026)
    Hentzen, C.
    The FUTURE study, a large randomised controlled trial in women with refractory overactive bladder, concluded that urodynamics does not improve outcomes when added to clinical assessment and is not cost-effective. These findings have been presented as justification for abandoning urodynamics in this large and heterogeneous patient population. In this paper, we undertake a detailed appraisal of the FUTURE study, examining its overarching research premise, the design and methodology it employed to evaluate the clinical utility of urodynamics and the way in which its findings were reported and interpreted by the authors. We conclude that significant conceptual and methodological limitations undermine the validity of the study and the reliability and generalisability of the data. Consequently, changes in clinical practice are not justified on the basis of the FUTURE study.