Researcher: Alper, Aydın
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Alper, Aydın
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Publication Metadata only Complications of laparoscopic and open donor hepatectomy for living donor liver transplantation: single center experience(Baskent University, 2024) Alim, Altan; Karataş, Cihan; Akbulut, Akın; Demir, Barış; Alper, Aydın; Kanmaz, Turan; School of Medicine; Koç University HospitalObjectives: Donor hepatectomy is a major surgery with a relatively safe profile and a reported complication rate of ~20%. Most complications are non-life threatening and are resolved with conservative measures. However, rare complications may need invasive precautions, ranging from percutaneous interventions to surgeries. Materials and Methods: We retrospectively analyzed all living donor hepatectomies at our center. Donors were divided into 2 groups: laparoscopic and open procedures. We collected preoperative, intraoperative and postoperative data of donors. Donor complications were recorded separately intraoperatively and postoperatively according to the Clavien-Dindo postoperative complication classification system. Results: Between July 2018 and April 2023, 215 living donors had hepatectomies, including 48 laparoscopic and 167 open donor hepatectomies. Among donors, 91 were female donors (42.3%) and 124 were male donors (57.7%). The mean age of all donors was 33.5 ± 8.1 years, and the mean body mass index (in kilogram divided by meters squared) was 24.6 ± 3.8. Among donors, 124 underwent right and 91 underwent left or left lateral hepatectomies. The mean operative time for all donors was 301 ± 83 minutes, the mean hospital stay was 5.8 ± 1.4 days, and the mean follow-up was 31.9 ± 15.8 months. Four patients (1.8%) had intraoperative complications, including 2 cases of bleeding, 1 diaphragm perforation, and 1 portal vein stenosis. Fourteen patients (7.4%) had major postoperative complications, with 5 patients requiring surgical intervention. Conclusions: Donor hepatectomy is a complicated surgery that requires extensive preoperative preparation and appropriate donor selection. Postoperative donor complications can be diagnosed early with close follow-up, and a multidisciplinary approach is essential for complication management. © Başkent University 2024 Printed in Turkey. All Rights Reserved.Publication Metadata only How can optimal cytoreduction rates increased over ninety percent with a minimal usage of neoadjuvant chemotherapy ?(Lippincott Williams and Wilkins (LWW), 2016) Onan, Anıl; Karataş, Funda; Bostancı, Esra; Kerem, Mustafa; Arvas, Macit; Güner, Haldun; Taşkıran, Çağatay; Mısırlıoğlu, Selim; Yıldız, Şule; Balık, Emre; Alper, Aydın; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 134190; N/A; 134205; 18758; 119809N/APublication Metadata only Contribution of gallbladder polyp surgery to treatment(Springer, 2017) Carilli, Şenol; Emre, Ali; Kaya, Aziz; Yaltı, Tunc; Kabaoglu, Burcak; N/A; N/A; N/A; N/A; Aliyazıcıoğlu, Tolga; Buğra, Dursun; Bilge, Orhan; Alper, Aydın; Doctor; Faculty Member; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; N/A; 1758; 176833; 119809Background Surgery is the preferred treatment for gallbladder polyps, not only for relieving the symptoms but also for eliminating the potential risk of malignancy. In our study, we investigated whether patients who had undergone surgery truly had a surgical indication and beyond question required laparoscopic cholecystectomy due to malignancy. Materials and methods 185 patients who were prediagnosed with gallbladder polyps were operated in VKV American Hospital, Istanbul between January 2004 and July 2015. Retrospective data of all patients included patients' age, gender, symptoms, preoperative ultrasonography, pathology reports, radiologic findings regarding the number and size of the polyps, and postoperative follow-up. Results 140 out of 185 patients were symptomatic before surgery. 85 patients (60.7 %) reported that their symptoms persisted after they had undergone surgery. 20 (14.3 %) of the patients with postoperatively persisting symptoms had no polyps in their pathologic examination. Only 35 out of 140 patients (25 %) reported relief of symptoms following surgery. Postoperative pathologic investigation revealed adenocarcinoma in only 1 patient and adenomatous polyps in 2 patients. Conclusion Postoperative pathologic investigations reveal only a very small percentage of premalignant and malignant polyps among patients who have undergone laparoscopic cholecystectomy. This finding clearly points out that we require new methods to differentiate cholesterol polyps from adenomatous polyps. Furthermore, the surgical indication criteria for patients with gall bladder polyps should be updated to prevent futile operations and morbidity.Publication Metadata only First laparoscopic donor hepatectomy cases of Turkey(Wiley, 2019) N/A; N/A; Karataş, Cihan; Alper, Aydın; Mecit, Nesimi; Kalayoğlu, Münci; Kanmaz, Turan; Doctor; Faculty Member; Doctor; Doctor; Faculty Member; N/A; School of Medicine; N/A; N/A; School of Medicine; Koç University Hospital; N/A; Koç University Hospital; Koç University Hospital; N/A; N/A; 119809; N/A; N/A; 275799N/APublication Metadata only Using O-Arm (TM) cholangiography in living donor liver transplantation(Lippincott Williams & Wilkins, 2022) Hoş, Gültekin; N/A; Karataş, Cihan; Alim, Altan; Yalçın, Ali Bektaş; Demir, Barış; Tırnova, İsmail; Akbulut, Akın; Alper, Aydın; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; Faculty Member; N/A; N/A; N/A; N/A; N/A; N/A; School of Medicine; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 119809; 275799N/APublication Metadata only The value of liver resection at primary, secondary or tertiary cytoreductive surgery for ovarian cancer(2016) Kerem, M.; Bostancı, S.; Karataş, F.; Dikmen, K.; Arvas, M.; Güner, H.; Onan, A.; Taşkıran, C.; N/A; Yıldız, Şule; Mısırlıoğlu, Selim; Alper, Aydın; Faculty Member; Doctor; N/A; School of Medicine; School of Medicine; N/A; Koc University Hospital, Koc University Hospital; Koc University Hospital; 134205; N/A; N/AN/A