Research Project: Protein-integrated white light-emitting diodes for efficient, high-quality and biocompatible solid-state lighting
Loading...
Contributors
Funders
ID
EC.00080
Authors
Nizamoğlu, Sedat
Faculty Member
Publications
Single transverse mode protein laser
(American Institute of Physics (AIP) Publishing, 2017) Begar, Efe; Çonkar, Deniz; Doğru-Yüksel, Itır Bakış; Jalali, Houman Bahmani; Karalar, Elif Nur Fırat; Nizamoğlu, Sedat; Min, Kyungtaek; Kim, Sunghwan; Umar, Muhammad; Department of Electrical and Electronics Engineering; Department of Molecular Biology and Genetics; Graduate School of Sciences and Engineering; Yes; College of Engineering; College of Sciences; GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
Here, we report a single transverse mode distributed feedback (DFB) protein laser. The gain medium that is composed of enhanced green fluorescent protein in a silk fibroin matrix yields a waveguiding gain layer on a DFB resonator. The thin TiO2 layer on the quartz grating improves optical feedback due to the increased effective refractive index. The protein laser shows a single transverse mode lasing at the wavelength of 520 nm with the threshold level of 92.1 mu J/mm(2).
Silk-hydrogel lenses for light-emitting diodes
(Nature Publishing Group (NPG), 2017) Nizamoğlu, Sedat; Yılgör, İskender; Melikov, Rustamzhon; Press, Daniel Aaron; Kumar, Baskaran Ganesh; Dogru, Itir Bakis; Sadeghi, Sadra; Chirea, Mariana; Department of Chemistry; Department of Electrical and Electronics Engineering; Yes; College of Engineering; College of Sciences
Today the high demand for electronics leads to massive production of waste, thus green materials based electronic devices are becoming more important for environmental protection and sustainability. The biomaterial based hydrogels are widely used in tissue engineering, but their uses in photonics are limited. In this study, silk fibroin protein in hydrogel form is explored as a bio-friendly alternative to conventional polymers for lens applications in light-emitting diodes. The concentration of silk fibroin protein and crosslinking agent had direct effects on optical properties of silk hydrogel. The spatial radiation intensity distribution was controlled via dome- and crater-type silk-hydrogel lenses. The hydrogel lens showed a light extraction efficiency over 0.95 on a warm white LED. The stability of silk hydrogel lens is enhanced approximately three-folds by using a biocompatible/biodegradable poly(ester-urethane) coating and more than three orders of magnitude by using an edible paraffin wax coating. Therefore, biomaterial lenses show promise for green optoelectronic applications.
Bioabsorbable polymer optical waveguides for deep-tissue photomedicine
(Nature Publishing Group (NPG), 2016) Nizamoğlu, Sedat; Gather, Malte C.; Humar, Matjaz; Choi, Myunghwan; Kim, Seonghoon; Kim, Ki Su; Hahn, Sei Kwang; Scarcelli, Giuliano; Randolph, Mark; Redmond, Robert W.; Yun, Seok Hyun.; Department of Electrical and Electronics Engineering; Yes; College of Engineering
Advances in photonics have stimulated significant progress in medicine, with many techniques now in routine clinical use. However, the finite depth of light penetration in tissue is a serious constraint to clinical utility. Here we show implantable light-delivery devices made of bio-derived or biocompatible, and biodegradable polymers. In contrast to conventional optical fibres, which must be removed from the body soon after use, the biodegradable and biocompatible waveguides may be used for long-term light delivery and need not be removed as they are gradually resorbed by the tissue. As proof of concept, we demonstrate this paradigm-shifting approach for photochemical tissue bonding (PTB). Using comb-shaped planar waveguides, we achieve a full thickness ( 410 mm) wound closure of porcine skin, which represents similar to 10-fold extension of the tissue area achieved with conventional PTB. The results point to a new direction in photomedicine for using light in deep tissues.
Biomaterial disk lasers by suppressing the coffee ring effect
(American Chemical Society (ACS), 2018) Doğru-Yüksel, Itır Bakış; Melikov, Rustamzhon; Nizamoğlu, Sedat; N/A; Department of Electrical and Electronics Engineering; Graduate School of Sciences and Engineering; KUYTAM (Koç University Surface Science and Technology Center); Yes; College of Engineering; GRADUATE SCHOOL OF SCIENCES AND ENGINEERING; Research Center
Inspired by the suppression of the coffee ring effect, we developed self-assembled disk lasers that can be formed with a wide variety of biomaterials. For proof of concept, we formed the disks with the natural protein silk fibroin or the synthetic biopolymer polyvinylpyrrolidone, which created a whispering gallery mode resonator that we combined with organic dyes for laser light generation. The lasers were flexible enough to bend around surfaces, physically transient in aqueous environments, and could be directly placed on various substrates. Moreover, the characteristics of laser emission could be modified by altering the size of the disk. Our results therefore highlight a new combination of materials that can be used in the environmentally friendly production of waste-free photonic devices.
Ecofriendly and efficient luminescent solar concentrators based on fluorescent proteins
(American Chemical Society, 2019) Çonkar, Deniz; Jalali, Houman Bahmani; Karalar, Elif Nur Fırat; Karatüm, Onuralp; Melikov, Rustamzhon; Nizamoğlu, Sedat; Sadeghi, Sadra; Srivastava, Shashi Bhushan; Department of Electrical and Electronics Engineering; Department of Molecular Biology and Genetics; Graduate School of Sciences and Engineering; Yes; College of Engineering; College of Sciences; GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
In recent years, luminescent solar concentrators (LSCs) have received renewed attention as a versatile platform for large-area, high-efficiency, and low-cost solar energy harvesting. So far, artificial or engineered optical materials, such as rare-earth ions, organic dyes, and colloidal quantum dots (QDs) have been incorporated into LSCs. Incorporation of nontoxic materials into efficient device architectures is critical for environmental sustainability and clean energy production. Here, we demonstrated LSCs based on fluorescent proteins, which are biologically produced, ecofriendly, and edible luminescent biomaterials along with exceptional optical properties. We synthesized mScarlet fluorescent proteins in Escherichia coli expression system, which is the brightest protein with a quantum yield of 61% in red spectral region that matches well with the spectral response of silicon solar cells. Moreover, we integrated fluorescent proteins in an aqueous medium into solar concentrators, which preserved their quantum efficiency in LSCs and separated luminescence and wave-guiding regions due to refractive index contrast for efficient energy harvesting. Solar concentrators based on mScarlet fluorescent proteins achieved an external LSC efficiency of 2.58%, and the integration at high concentrations increased their efficiency approaching to 5%, which may facilitate their use as “luminescent solar curtains” for in-house applications. The liquid-state integration of proteins paves a way toward efficient and “green” solar energy harvesting.
