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Modeling and analysis of Gab1 mediated feedback loops to understand Gab's role in erk-akt signaling and cance

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dc.contributor.departmentDepartment of Chemical and Biological Engineering
dc.contributor.kuauthorArkun, Yaman
dc.contributor.kuprofileFaculty Member
dc.contributor.otherDepartment of Chemical and Biological Engineering
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.yokid108526
dc.date.accessioned2024-11-09T23:53:35Z
dc.date.issued2019
dc.description.abstractA mathematical model is presented to study the dynamics of the docking protein Gab1 that plays an important role in the regulation of ERK and AKT signaling pathways. Model predictions can be used to understand the role of Gab1 in the development of cancer which can give insight into targeted therapy.
dc.description.indexedbyWoS
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TÜBİTAK)
dc.identifier.doiN/A
dc.identifier.eissn1558-4615
dc.identifier.isbn978-1-5386-1311-5
dc.identifier.issn1557-170X
dc.identifier.quartileN/A
dc.identifier.urihttps://hdl.handle.net/20.500.14288/15051
dc.identifier.wos557295303084
dc.languageEnglish
dc.publisherIEEE
dc.relation.grantno117F123
dc.source2019 41st Annual International Conference of The IEEE Engineering in Medicine and Biology Society (EMBC)
dc.subjectEngineering,biomedical
dc.subjectEngineering, electrical and electronic
dc.titleModeling and analysis of Gab1 mediated feedback loops to understand Gab's role in erk-akt signaling and cance
dc.typeConference proceeding
dspace.entity.typePublication
local.contributor.authorid0000-0002-3740-379X
local.contributor.kuauthorArkun, Yaman
relation.isOrgUnitOfPublicationc747a256-6e0c-4969-b1bf-3b9f2f674289
relation.isOrgUnitOfPublication.latestForDiscoveryc747a256-6e0c-4969-b1bf-3b9f2f674289

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