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Basilar artery occlusion management: an international survey of middle versus high-income countries

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Drumm B., Herning A., Klein P., Raymond J., Abdalkader M., Huo X., Chen Y., Siegler J.E., Peacock M., Schonewille W.J., Liu X., Hu W., Ji X., Li C., Alemseged F., Liu L., Nagel S., Strbian D., Rebello L.C., Yaghi S., Qureshi M.M., Fischer U., Tsivgoulis G., Kaesmacher J., Yamagami H., Puetz V., Sylaja P.N., Marto J.P., Sacco S., Kristoffersen E.S., Demeestere J., Conforto A.B., Meyer L., Kaiser D.P.O., Reiff T., Romoli M., Diana F., Lobotesis K., Roi D., Masoud H.E., Ma A., Mohammaden M.H., Doheim M.F., Zhu Y., Sang H., Sun D., Ton M.D., Raynald, Li F., Lapergue B., Hanning U., Yang Q., Lee J.S., Thomalla G., Yang P., Liu J., Campbell B.C.V., Chen H.-S., Zaidat O.O., Qiu Z., Nogueira R.G., Miao Z., Nguyen T.N., Banerjee S.

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Background and Purpose: Two early basilar artery occlusion (BAO) randomized controlled trials (RCTs) did not establish the superiority of endovascular thrombectomy (EVT) over medical management. Yet many providers continued to recommend EVT. The goal of the present article is to compare physicians’ diagnostic and management strategies of BAO among middle-income and high-income countries (MICs and HICs, respectively). Methods: We conducted an international survey from January to March 2022 regarding management strategies in acute BAO, to examine clinical and imaging parameters influencing clinician management of patients with BAO. We compared responses between physicians from HIC and MIC. Results: Among the 1245 respondents from 73 countries, 799 (64.2%) were from HIC, with the remaining 393 (31.6%) from MIC. Most respondents perceived that EVT was superior to medical management for acute BAO, but more so in respondents from HIC (98.0% vs. 94.2%, p < 0.01). MIC respondents were more likely to believe further RCTs were warranted (91.6% vs. 74.0%, p < 0.01) and were more likely to find it acceptable to enroll any patient who met a trial’s criteria in the standard medical treatment arm (58.8% vs. 38.5%, p < 0.01). Conclusions: In an area where clinical equipoise was called into question despite the lack of RCT evidence, we found that respondents from MIC were more likely to express willingness to enroll patients with BAO in an RCT than their HIC counterparts. © The Author(s) 2022.

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SAGE Publications Inc.

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Interventional Neuroradiology

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10.1177/15910199221143190

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Over the last 15 years, the number of childhood deaths has been cut in half. This proves that it is possible to win the fight against almost every disease. Still, we are spending an astonishing amount of money and resources on treating illnesses that are surprisingly easy to prevent. The new goal for worldwide Good Health promotes healthy lifestyles, preventive measures and modern, efficient healthcare for everyone.
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