Publication: Synthesis, structural aspects, and antimicrobial activity investigation of novel macrocyclic amide-containing compounds
Program
KU-Authors
KU Authors
Co-Authors
Aghatabay, N. M.
Gunduz, S.
Turkyilmaz, M.
Karabulut, H. R. F.
Dulger, B.
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Abstract
Macrocyclic 1(6),7(6)-dimethyl-1,7(2,4)-ditriazina-2,6,8,12-tetraaza-3,5,9,11-tetraoxocyclododecaphane, 1(6),8(6)-dimethyl-1,8(2,4)-ditriazina-2,7,9,14-tetraaza-3,6,10,13-tetraoxocyclotetradecaphane, 1(6),9(6)-dimethyl-1,9(2,4)-ditriazina-2,8,10,16-tetraaza-3,7,11,15-tetraoxocyclohexadecaphane, and 1(6),10(6)-dimethyl-1,10(2,4)-ditriazina-2,9,11,18-tetraaza-3,8,12,17-tetraoxocyclooctadecaphane are synthesized. The compounds are characterized by elemental analyses, Raman, IR, H-1, C-13 NMR and mass spectral data. The antimicrobial activities of the compounds are evaluated against several bacteria and yeast cultures and the results were compared with those of commercial antibiotic and antifungal agents. Structure-activity relationships are also discussed.
Source
Publisher
Springer
Subject
Chemistry, organic
Citation
Has Part
Source
Chemistry of Heterocyclic Compounds
Book Series Title
Edition
DOI
10.1007/s10593-012-1080-5
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