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Ulceration vs. Mitosis in cutaneous melanoma: which is superior for predicting prognosis across clinical stages?

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dc.contributor.coauthorTas, Faruk
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorErtürk, Kayhan
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:28:05Z
dc.date.issued2022
dc.description.abstractUlceration and high mitosis are considered among the major unfavorable prognostic factors in the survival of cutaneous melanoma patients. The aim of this study was to investigate the clinical significance of these parameters and to compare them to see which one is superior to predicting prognosis across all clinical stages of melanoma. A total of 1,074 melanomas were analyzed retrospectively. Tumor ulceration was found to be limited to the local stage for predicting survival, whereas, mitosis maintained its prognostic strength for predicting survival across all clinical stages. Furthermore, no survival differences were observed between ulceration and mitosis across clinical stages.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue10
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume40
dc.identifier.doi10.1080/07357907.2022.2133139
dc.identifier.eissn1532-4192
dc.identifier.issn0735-7907
dc.identifier.scopus2-s2.0-85139868058
dc.identifier.urihttps://doi.org/10.1080/07357907.2022.2133139
dc.identifier.urihttps://hdl.handle.net/20.500.14288/11828
dc.identifier.wos867592600001
dc.keywordsMelanoma
dc.keywordsUlceration
dc.keywordsMitosis
dc.keywordsSurvival
dc.keywordsPrognostic American Joint Committee
dc.keywordsTumor mitotic rate
dc.keywordsStaging system
dc.language.isoeng
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCancer Investigation
dc.subjectOncology
dc.titleUlceration vs. Mitosis in cutaneous melanoma: which is superior for predicting prognosis across clinical stages?
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorErtürk, Kayhan
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
local.publication.orgunit2School of Medicine
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