Early evaluation of cardiac functions by conventional echocardiography in children and adolescents with type 1 diabetes

Abstract

Objective: It is known that cardiac dysfunction is one of the serious and common complications of type 1 diabetes. The aim of this study was to evaluation early cardiac functions of children and adolescents with type 1 diabetes by conventional echocardiography.

Material and Methods: This study included 53 children and adolescents with type 1 diabetes and 55 age-sex matched healty children and adolescents. The values of height, weight, body-mass index and blood pressure of the all participants were recorded. Glycated hemoglobin measuring was performed for glycemic control in patients with type 1 diabetes. Myocardial systolic and diastolic functions of all paticipants were assessed by conventional echocardiography.

Results: A wave velocity of tricuspid valve was significantly higher (p=0,04) and tricuspid E/A rate was significantly less (p=0,02) in patients with type 1 diabetes than controls. Fractional shortening and ejection fraction of left ventricular revealed less in the patient groups than controls, but they were no statistically significant differences (p values 0,675,0,933 respectively). Statistically significant negative correlation was noted between level of glycated hemoglobin and ejection fraction of left ventricular in patients group (p=0,049, r= -0,669).

Conclusion: Determination of right ventricular diastolic dysfunction and negative corrrelation between level of glycated hemoglobin and left ventricular ejection fraction in children and adolescents with type 1 diabetes suggest, that cardiac evaluation of poor glycemic controlled diabetic patients is necessary periodically performing by echocardiography, which is noninvasive diagnostic method.