Publication: Point-of-care diagnostic platforms for loop-mediated isothermal amplification
dc.contributor.coauthor | Munzer Alseed, Muhammad | |
dc.contributor.coauthor | Yetisen, Ali K. | |
dc.contributor.department | KUTTAM (Koç University Research Center for Translational Medicine) | |
dc.contributor.department | Department of Mechanical Engineering | |
dc.contributor.department | KUAR (KU Arçelik Research Center for Creative Industries) | |
dc.contributor.department | Graduate School of Sciences and Engineering | |
dc.contributor.kuauthor | Atçeken, Nazente | |
dc.contributor.kuauthor | Taşoğlu, Savaş | |
dc.contributor.kuauthor | Dabbagh, Sajjad Rahmani | |
dc.contributor.schoolcollegeinstitute | College of Engineering | |
dc.contributor.schoolcollegeinstitute | GRADUATE SCHOOL OF SCIENCES AND ENGINEERING | |
dc.contributor.schoolcollegeinstitute | Research Center | |
dc.date.accessioned | 2025-01-19T10:28:28Z | |
dc.date.issued | 2023 | |
dc.description.abstract | The loop-mediated isothermal amplification (LAMP) method is one of the Nucleic acid amplification tests (NAATs) that allows for the amplification of target regions without using a thermal cycle. With its unique primer design, LAMP ensures the rapid replication of the targeted DNA region with high specificity and high efficiency. LAMP technology is used for diagnostic purposes in pathogen detection due to its ease of use, low cost, and simplicity without requiring complex equipment. A wide range of LAMP diagnostic platforms have been developed for applications in bacteria, virus, and parasitic pathogen detection. Herein, the methodology of LAMP technology and its applications in pathogen detection and SNP genotyping and mutation detection are discussed. Point-of-care (PoC) LAMP platforms designed with the principles of microfluidic chip technology, including LAMP-on-a-chip, paper-based LAMP, and smartphone-based LAMP applications have been elaborated. LAMP technology represents a fast, robust, and reliable diagnostic platform for point-of-care testing. | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.issue | 8 | |
dc.description.openaccess | All Open Access; Hybrid Gold Open Access | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.sponsorship | Funding text 1: N.A. and M.M.A. contributed equally to this work. S.T. acknowledges Tubitak 2232 International Fellowship for Outstanding Researchers Award (118C391), Alexander von Humboldt Research Fellowship for Experienced Researchers, Marie Skłodowska-Curie Individual Fellowship (101003361), and Royal Academy Newton-Katip Çelebi Transforming Systems Through Partnership award (120N019) for financial support of this research. Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the TÜBİTAK. This work was partially supported by Science Academy's Young Scientist Awards Program (BAGEP), Outstanding Young Scientists Awards (GEBİP), and Bilim Kahramanlari Dernegi The Young Scientist Award. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.; Funding text 2: N.A. and M.M.A. contributed equally to this work. S.T. acknowledges Tubitak 2232 International Fellowship for Outstanding Researchers Award (118C391), Alexander von Humboldt Research Fellowship for Experienced Researchers, Marie Skłodowska‐Curie Individual Fellowship (101003361), and Royal Academy Newton‐Katip Çelebi Transforming Systems Through Partnership award (120N019) for financial support of this research. Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the TÜBİTAK. This work was partially supported by Science Academy's Young Scientist Awards Program (BAGEP), Outstanding Young Scientists Awards (GEBİP), and Bilim Kahramanlari Dernegi The Young Scientist Award. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. | |
dc.description.volume | 25 | |
dc.identifier.doi | 10.1002/adem.202201174 | |
dc.identifier.issn | 1438-1656 | |
dc.identifier.quartile | Q2 | |
dc.identifier.scopus | 2-s2.0-85143914565 | |
dc.identifier.uri | https://doi.org/10.1002/adem.202201174 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/25732 | |
dc.identifier.wos | 898412100001 | |
dc.keywords | LAMP-on-a-chip | |
dc.keywords | Loop-mediated isothermal amplification (LAMP) | |
dc.keywords | Paper-based LAMP | |
dc.keywords | Pathogen detection | |
dc.keywords | Point-of-care LAMP (PoC-LAMP) diagnostics | |
dc.keywords | Smartphone-based LAMP | |
dc.language.iso | eng | |
dc.publisher | John Wiley and Sons Inc | |
dc.relation.grantno | Bilim Kahramanlari Dernegi; Royal Academy, (120N019); Alexander von Humboldt-Stiftung, AvH, (101003361); Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK; Bilim Akademisi | |
dc.relation.ispartof | Advanced Engineering Materials | |
dc.subject | Materials science, multidisciplinary | |
dc.title | Point-of-care diagnostic platforms for loop-mediated isothermal amplification | |
dc.type | Review | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Atçeken, Nazente | |
local.contributor.kuauthor | Dabbagh, Sajjad Rahmani | |
local.contributor.kuauthor | Taşoğlu, Savaş | |
local.publication.orgunit1 | GRADUATE SCHOOL OF SCIENCES AND ENGINEERING | |
local.publication.orgunit1 | College of Engineering | |
local.publication.orgunit1 | Research Center | |
local.publication.orgunit2 | Department of Mechanical Engineering | |
local.publication.orgunit2 | KUAR (KU Arçelik Research Center for Creative Industries) | |
local.publication.orgunit2 | KUTTAM (Koç University Research Center for Translational Medicine) | |
local.publication.orgunit2 | Graduate School of Sciences and Engineering | |
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