Publication:
Effect of the premedication with oral clonidine on surgical comfort in patients undergoing fess due to advanced nasal polyposis: a randomized double blind clinical trial

dc.contributor.coauthorTugrul, Selahattin
dc.contributor.coauthorDogan, Remzi
dc.contributor.coauthorSenturk, Erol
dc.contributor.coauthorSezen, Seda
dc.contributor.coauthorBakan, Mefkur
dc.contributor.coauthorOzturan, Orhan
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.kuauthorKoçak, İlker
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.date.accessioned2024-11-09T22:56:17Z
dc.date.issued2016
dc.description.abstractObjective: The objective of this randomized double blind study was to evaluate effect of the premedication with oral clonidine on blood pressure, cleaning of surgical site and bleeding in the ESS performed due to advanced NP. Methods: A total of 52 patients who underwent functional endoscopic sinus surgery (FESS) due to Kennedy grade 4 nasal polyposis (NP) were included. Patients were randomized into two groups. Group 1(n = 26) received 0.2 mg oral clonodine one hour before the operation in addition to standard anesthesia procedure. Group 2 (n = 26) was administered standard anesthesia procedure alone. The amount of bleeding during surgery, cleaning of surgical site and surgeon's satisfaction were evaluated in comparison between the groups. Results: The amount of bleeding and mean arterial pressure were significantly lower in the Group 1 compared to the Group 2. The deaning of surgical site was found to be significantly better and surgeon's satisfaction significantly higher in the Group 1 than in the Group 2. Systolic, diastolic and mean arterial pressures during surgery were significantly lower in the Group 1 compared to the Group 2. Conclusion: Premedication with oral donidine provides a dearer view of surgical site, reduces the amount of bleeding and significantly increases surgeon's satisfaction during the operation in FESS performed due to NP. Premedication with oral donidine is a safe, inexpensive and effective methods in order to increase the surgical success and comfort and reduce complications in the FESS surgery.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue6
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume37
dc.identifier.doi10.1016/j.amjoto.2016.08.008
dc.identifier.eissn1532-818X
dc.identifier.issn0196-0709
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-84992116184
dc.identifier.urihttps://doi.org/10.1016/j.amjoto.2016.08.008
dc.identifier.urihttps://hdl.handle.net/20.500.14288/7354
dc.identifier.wos387736600013
dc.keywordsEndoscopic sinus surgery
dc.keywordsHypotensive anesthesia
dc.keywordsField
dc.keywordsScale
dc.language.isoeng
dc.publisherW B Saunders Co-Elsevier Inc
dc.relation.ispartofAmerican Journal of Otolaryngology
dc.subjectOtorhinolaryngology
dc.titleEffect of the premedication with oral clonidine on surgical comfort in patients undergoing fess due to advanced nasal polyposis: a randomized double blind clinical trial
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorKoçak, İlker
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
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relation.isParentOrgUnitOfPublication055775c9-9efe-43ec-814f-f6d771fa6dee
relation.isParentOrgUnitOfPublication.latestForDiscovery055775c9-9efe-43ec-814f-f6d771fa6dee

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