Publication:
Pregnancy and breast cancer in young women: current updates and future directions

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dc.contributor.coauthorZhang, Shiliang (57816042300)
dc.contributor.coauthorGuclu, Sena B. (60111982200)
dc.contributor.coauthorLipsyc-Sharf, Marla (57215546569)
dc.contributor.coauthorKapoor, Nimmi S. (42761631100)
dc.date.accessioned2025-12-31T08:23:28Z
dc.date.available2025-12-31
dc.date.issued2025
dc.description.abstractThe relationship between pregnancy and breast cancer is complicated. On one hand, pregnancy can influence breast cancer risk and tumor biology, and on the other, a breast cancer diagnosis and its subsequent management can significantly affect fertility, family planning, and future pregnancies. This interaction presents challenges unique to young women with breast cancer (YWBC). This review provides an updated overview of YWBC and pregnancy-associated breast cancer (PABC), including the rising prevalence of YWBC, current understanding of the biology of PABC and its subtypes, and the management of PABC. We address the critical issue of how breast cancer treatment impacts family planning and future pregnancies, including current data on interrupting endocrine treatment for pregnancy. Additionally, we examine recent advancements in early-stage breast cancer as well as gaps in knowledge regarding how targeted treatments affect ovarian reserve. Finally, we highlight key areas of future research that could improve the prevention, management, and understanding of cancer treatment’s impact on fertility in YWBC. © 2025 Elsevier B.V., All rights reserved.
dc.description.fulltextYes
dc.description.harvestedfromManual
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.identifier.doi10.1177/17588359251369973
dc.identifier.eissn1758-8359
dc.identifier.embargoNo
dc.identifier.issn1758-8340
dc.identifier.quartileN/A
dc.identifier.scopus2-s2.0-105016843770
dc.identifier.urihttps://doi.org/10.1177/17588359251369973
dc.identifier.urihttps://hdl.handle.net/20.500.14288/31731
dc.identifier.volume17
dc.keywordsBreast Cancer
dc.keywordsChemotherapy
dc.keywordsHormone Therapy
dc.keywordsPostpartum
dc.keywordsPregnancy
dc.keywordsTargeted Therapy
dc.keywordsBreast Cancer
dc.keywordsCancer Diagnosis
dc.keywordsCancer Risk
dc.keywordsDrug Therapy
dc.keywordsFamily Planning
dc.keywordsFemale
dc.keywordsHormonal Therapy
dc.keywordsHuman
dc.keywordsOpen Access
dc.keywordsOvarian Reserve
dc.keywordsPregnancy
dc.keywordsPrevalence
dc.keywordsPrevention
dc.keywordsReview
dc.keywordsTherapy
dc.language.isoeng
dc.publisherSAGE Publications Inc.
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofTherapeutic Advances in Medical Oncology
dc.relation.openaccessYes
dc.rightsCC BY-NC-ND (Attribution-NonCommercial-NoDerivs)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.titlePregnancy and breast cancer in young women: current updates and future directions
dc.typeReview
dspace.entity.typePublication

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