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Low cost flatbed scanner label-free biosensor

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dc.contributor.coauthorAvcı, Oğuzhan
dc.contributor.coauthorSeymour, Elif
dc.contributor.coauthorSevenler, Derin D.
dc.contributor.coauthorÜnlü, M. Selim
dc.contributor.coauthorÖzkumur, Ayça Yalçın
dc.contributor.departmentDepartment of Electrical and Electronics Engineering
dc.contributor.kuauthorAygün, Uğur
dc.contributor.kuauthorÜrey, Hakan
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.date.accessioned2024-11-09T12:40:09Z
dc.date.issued2016
dc.description.abstractIn this paper, we demonstrate utilization of a commercial flatbed document scanner as a label-free biosensor for high-throughput imaging of DNA and protein microarrays. We implemented an interferometric sensing technique through use of a silicon/oxide layered substrate, and easy to implement hardware modifications such as re-aligning moving parts and inserting a custom made sample plate. With a cost as low as 100USD, powered by a USB cable, and scan speed of 30 seconds for a 4mm x 4 mm area with similar to 10 mu m lateral resolution, the presented system offers a super low cost, easy to use alternative to commercially available label-free systems.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.identifier.doi10.1117/12.2214113
dc.identifier.eissn1996-756X
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR00701
dc.identifier.isbn978-1-62841-933-7
dc.identifier.issn0277-786X
dc.identifier.quartileN/A
dc.identifier.scopus2-s2.0-84973439863
dc.identifier.urihttps://hdl.handle.net/20.500.14288/2163
dc.identifier.wos378119600005
dc.keywordsOptical biosensor
dc.keywordsLabel-free
dc.keywordsDNA / protein microarray
dc.keywordsFlatbed scanner
dc.language.isoeng
dc.publisherSociety of Photo-optical Instrumentation Engineers (SPIE)
dc.relation.ispartofProceedings of SPIE
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/704
dc.subjectMicroscopy
dc.subjectOptics
dc.subjectRadiology
dc.titleLow cost flatbed scanner label-free biosensor
dc.typeConference Proceeding
dspace.entity.typePublication
local.contributor.kuauthorAygün, Uğur
local.contributor.kuauthorÜrey, Hakan
local.publication.orgunit1College of Engineering
local.publication.orgunit2Department of Electrical and Electronics Engineering
relation.isOrgUnitOfPublication21598063-a7c5-420d-91ba-0cc9b2db0ea0
relation.isOrgUnitOfPublication.latestForDiscovery21598063-a7c5-420d-91ba-0cc9b2db0ea0
relation.isParentOrgUnitOfPublication8e756b23-2d4a-4ce8-b1b3-62c794a8c164
relation.isParentOrgUnitOfPublication.latestForDiscovery8e756b23-2d4a-4ce8-b1b3-62c794a8c164

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