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Low cost flatbed scanner label-free biosensor

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dc.contributor.coauthorAvcı, Oğuzhan
dc.contributor.coauthorSeymour, Elif
dc.contributor.coauthorSevenler, Derin D.
dc.contributor.coauthorÜnlü, M. Selim
dc.contributor.coauthorÖzkumur, Ayça Yalçın
dc.contributor.departmentDepartment of Electrical and Electronics Engineering
dc.contributor.kuauthorAygün, Uğur
dc.contributor.kuauthorÜrey, Hakan
dc.contributor.kuprofileFaculty Member
dc.contributor.otherDepartment of Electrical and Electronics Engineering
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.yokidN/A
dc.contributor.yokid8579
dc.date.accessioned2024-11-09T12:40:09Z
dc.date.issued2016
dc.description.abstractIn this paper, we demonstrate utilization of a commercial flatbed document scanner as a label-free biosensor for high-throughput imaging of DNA and protein microarrays. We implemented an interferometric sensing technique through use of a silicon/oxide layered substrate, and easy to implement hardware modifications such as re-aligning moving parts and inserting a custom made sample plate. With a cost as low as 100USD, powered by a USB cable, and scan speed of 30 seconds for a 4mm x 4 mm area with similar to 10 mu m lateral resolution, the presented system offers a super low cost, easy to use alternative to commercially available label-free systems.
dc.description.fulltextYES
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.formatpdf
dc.identifier.doi10.1117/12.2214113
dc.identifier.eissn1996-756X
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR00701
dc.identifier.isbn978-1-62841-933-7
dc.identifier.issn0277-786X
dc.identifier.linkhttps://doi.org/10.1117/12.2214113
dc.identifier.quartileN/A
dc.identifier.scopus2-s2.0-84973439863
dc.identifier.urihttps://hdl.handle.net/20.500.14288/2163
dc.identifier.wos378119600005
dc.keywordsOptical biosensor
dc.keywordsLabel-free
dc.keywordsDNA / protein microarray
dc.keywordsFlatbed scanner
dc.languageEnglish
dc.publisherSociety of Photo-optical Instrumentation Engineers (SPIE)
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/704
dc.sourceProceedings of SPIE
dc.subjectMicroscopy
dc.subjectOptics
dc.subjectRadiology
dc.titleLow cost flatbed scanner label-free biosensor
dc.typeConference proceeding
dspace.entity.typePublication
local.contributor.authoridN/A
local.contributor.authorid0000-0002-2031-7967
local.contributor.kuauthorAygün, Uğur
local.contributor.kuauthorÜrey, Hakan
relation.isOrgUnitOfPublication21598063-a7c5-420d-91ba-0cc9b2db0ea0
relation.isOrgUnitOfPublication.latestForDiscovery21598063-a7c5-420d-91ba-0cc9b2db0ea0

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