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New results on the melting thermodynamics of a circular DNA chain

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dc.contributor.coauthorOrlandini, E.
dc.contributor.coauthorMukamel, D.
dc.contributor.departmentDepartment of Physics
dc.contributor.facultymemberYes
dc.contributor.kuauthorKabakçıoğlu, Alkan
dc.contributor.schoolcollegeinstituteCollege of Sciences
dc.date.accessioned2024-11-09T23:05:44Z
dc.date.issued2010
dc.description.abstractWe investigate the impact of supercoil period and nonzero supercoil formation energy on the thermal denaturation of a circular DNA. Our analysis is based on a recently proposed generalization of the Poland–Scheraga model that allows the DNA melting to be studied for plasmids with circular topology, where denaturation is accompanied by formation of supercoils. We find that the previously obtained first-order melting transition persists under the generalization discussed. The dependence of the size of the order-parameter jump at the transition point and the associated melting temperature are obtained analytically.
dc.description.fulltextNo
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.openaccessNO
dc.description.peerreviewstatusN/A
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipWe thank an anonymous referee for valuable suggestions. This work is dedicated to Prof. Nihat Berker on the occasion of his 60th birthday. It is partially supported by the Scientific and Technological Research Council of Turkey (TUBITAK) through Grant No. TBAG-108T553.
dc.description.studentonlypublicationNo
dc.description.studentpublicationNo
dc.description.versionN/A
dc.identifier.WoSQuartileQ2
dc.identifier.doi10.1016/j.physa.2009.12.063
dc.identifier.eissn1873-2119
dc.identifier.embargoN/A
dc.identifier.endpage3006
dc.identifier.grantnoTBAG-108T553
dc.identifier.issn0378-4371
dc.identifier.issue15
dc.identifier.scopus2-s2.0-81555216065
dc.identifier.startpage3002
dc.identifier.urihttps://doi.org/10.1016/j.physa.2009.12.063
dc.identifier.urihttps://hdl.handle.net/20.500.14288/8860
dc.identifier.volume389
dc.identifier.wos000279491200025
dc.keywordsDNA denaturation
dc.keywordsCircular DNA
dc.keywordsSupercoil
dc.keywordsPoland-Scheraga model
dc.keywordsThermal denaturation
dc.keywordsDNA melting
dc.language.isoeng
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofPhysica A-Statistical Mechanics and Its Applications
dc.relation.openaccessN/A
dc.rightsN/A
dc.subjectPhysics
dc.subjectDNA thermal denaturation
dc.subjectCircular DNA topology
dc.subjectDNA melting transition
dc.titleNew results on the melting thermodynamics of a circular DNA chain
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorKabakçıoğlu, Alkan
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