Publication: Treatment outcome and mortality among geriatric patients diagnosed with multiple-drug resistant tuberculosis: a comparative analysis from a tertiary referral center
dc.contributor.coauthor | Onur, Seda Tural | |
dc.contributor.coauthor | Ortaköylü, Mediha Gönenç | |
dc.contributor.coauthor | Alkan, Figen | |
dc.contributor.department | KUH (Koç University Hospital) | |
dc.contributor.kuauthor | İliaz, Sinem | |
dc.contributor.schoolcollegeinstitute | KUH (KOÇ UNIVERSITY HOSPITAL) | |
dc.date.accessioned | 2024-11-09T11:37:54Z | |
dc.date.issued | 2021 | |
dc.description.abstract | Aim: multidrug-resistant (MDR) tuberculosis (TB) and drug-sensitive-TB have long treatment periods which affect patient compliance and treatment outcomes. We planned to determine the factors that will affect the management of this disease in the elderly population. Methods: in a period of two years, a total of 82 elderly patients with bacteriologically proven TB enrolled into our retrospective study between 2011-2018. The patients' demographic features, laboratory findings, and hospital records were analyzed. Results: we enrolled 67 (87.7%) patients with drug-sensitive TB and 15 (18.2%) MDR-TB in our study. In the study population, 73.2% (n=60) were male and the mean age was 75 +/- 9 years. When we compare treatment complications of MDR-TB and drug-sensitive-TB, we found out the rate of electrolyte imbalance, nephrotoxicity, and ocular toxicity more common among the MDR-TB group (p=0.008, p=0.008, and p=0.032, respectively). When we compare the mortality rate, cure, and treatment success between MDR-TB and drug sensitive TB, there were no statistically significant results (p=0.898, p=0.549, p=0.488; respectively). Conclusion: however, we think that this was due to the low sample size. Nevertheless, we should be careful in terms of complications management of the geriatric population. | |
dc.description.fulltext | YES | |
dc.description.indexedby | WOS | |
dc.description.indexedby | Scopus | |
dc.description.indexedby | TR Dizin | |
dc.description.openaccess | YES | |
dc.description.publisherscope | National | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.sponsorship | N/A | |
dc.description.version | Publisher version | |
dc.description.volume | 59 | |
dc.identifier.doi | 10.4274/haseki.galenos.2021.7596 | |
dc.identifier.eissn | 2147-2688 | |
dc.identifier.embargo | NO | |
dc.identifier.filenameinventoryno | IR03409 | |
dc.identifier.issn | 1302-0072 | |
dc.identifier.quartile | N/A | |
dc.identifier.scopus | 2-s2.0-85120671032 | |
dc.identifier.uri | https://doi.org/10.4274/haseki.galenos.2021.7596 | |
dc.identifier.wos | 729649700005 | |
dc.keywords | Geriatric | |
dc.keywords | Mortality | |
dc.keywords | Pulmonary | |
dc.keywords | Tuberculosis | |
dc.keywords | Multidrug resistant | |
dc.language.iso | eng | |
dc.publisher | Galenos Yayınevi | |
dc.relation.grantno | NA | |
dc.relation.ispartof | The Medical Bulletin of Haseki / Haseki Tıp Bülteni | |
dc.relation.uri | http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10195 | |
dc.subject | General and internal medicine | |
dc.title | Treatment outcome and mortality among geriatric patients diagnosed with multiple-drug resistant tuberculosis: a comparative analysis from a tertiary referral center | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | İliaz, Sinem | |
local.publication.orgunit1 | KUH (KOÇ UNIVERSITY HOSPITAL) | |
local.publication.orgunit2 | KUH (Koç University Hospital) | |
relation.isOrgUnitOfPublication | f91d21f0-6b13-46ce-939a-db68e4c8d2ab | |
relation.isOrgUnitOfPublication.latestForDiscovery | f91d21f0-6b13-46ce-939a-db68e4c8d2ab | |
relation.isParentOrgUnitOfPublication | 055775c9-9efe-43ec-814f-f6d771fa6dee | |
relation.isParentOrgUnitOfPublication.latestForDiscovery | 055775c9-9efe-43ec-814f-f6d771fa6dee |
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