Publication:
Thalamic neuronal activity correlated with essential tremor

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dc.contributor.coauthorHua, S.E.
dc.contributor.coauthorLenz, F.A.
dc.contributor.coauthorReich, S.G.
dc.contributor.coauthorDougherty, P.M.
dc.contributor.departmentN/A
dc.contributor.kuauthorZırh, Tahsin Ali
dc.contributor.kuprofileDoctor
dc.contributor.schoolcollegeinstituteN/A
dc.contributor.yokidN/A
dc.date.accessioned2024-11-10T00:06:21Z
dc.date.issued1998
dc.description.abstractAnimal studies suggest that an olivocerebello-bulbospinal pathway mediates harmaline induced tremor, which resembles essential tremor in humans. However, recent evidence suggests that thalamocortical pathways participate in essential tremor. Thalamic single neuron activity has been analysed during thalamotomy for essential tremor. It has been shown by spectral cross correlation analysis that thalamic activity has a significant, linear relation to forearm EMG activity during tremor. The presence of this tremor related activity at the site where a lesion abolishes essential tremor suggests that the thalamus has an important role in the mechanism of essential tremor.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue2
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsorshipNINDS NIH HHS [R29 NS28598, P01 NS32386-PROJ 1, K08 NS01384] Funding Source: Medline
dc.description.volume64
dc.identifier.doi10.1136/jnnp.64.2.273
dc.identifier.issn0022-3050
dc.identifier.scopus2-s2.0-0031898679
dc.identifier.urihttp://dx.doi.org/10.1136/jnnp.64.2.273
dc.identifier.urihttps://hdl.handle.net/20.500.14288/16581
dc.identifier.wos71993200031
dc.keywordsEssential Tremor
dc.keywordsThalamus
dc.keywordsSpectral Cross Correlation Analysis
dc.keywordsThalamotomy
dc.keywordsParkinsonian Tremor
dc.keywordsStereotaxic Thalamotomy
dc.keywordsNuclear
dc.languageEnglish
dc.publisherBritish Med Journal Publ Group
dc.sourceJournal of Neurology Neurosurgery and Psychiatry
dc.subjectClinical neurology
dc.subjectPsychiatry
dc.subjectSurgery
dc.titleThalamic neuronal activity correlated with essential tremor
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authoridN/A
local.contributor.kuauthorZırh, Tahsin Ali

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