Publication:
Room-temperature apo structure of human SIRT2 solved by X-RAY crystallography and its application in targeted cancer drug development

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dc.contributor.advisorDemirci, Hasan
dc.contributor.kuauthorPaydos, Seyide Seda
dc.contributor.programMolecular Biology and Genetics
dc.contributor.refereeÇiftçi, Halil İbrahim
dc.contributor.refereeÖztaş, Onur
dc.contributor.refereeSever, Belgin
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.coverage.spatialİstanbul
dc.date.accessioned2026-09-10T10:13:15Z
dc.date.issued2025
dc.description.fulltextYes
dc.format.extentxi, 57 leaves ;; 30 cm.
dc.identifier.embargoNo
dc.identifier.endpage68
dc.identifier.filenameinventorynoT_2025_098_GSSE
dc.identifier.urihttps://hdl.handle.net/20.500.14288/35249
dc.identifier.yoktezid974347
dc.identifier.yoktezlinkhttps://tez.yok.gov.tr/UlusalTezMerkezi/TezGoster?key=V-oEQd0LkkqRGCXNzJWCTWJ1PwKavfmYkLB0NYcy0UGLdRgLBLZpGF05LTgn_Ei1
dc.keywordsSIRT2, Sirtuins, NAD⁺-dependent deacetylases, Protein structure, X-ray crystallography, Apo structure, Room-temperature crystallography
dc.keywordsAnahtar kelimeler: Sirtuins, SIRT2, Apo yapı, Protein konformasyonu, X-ışını kristalografisi.;
dc.languageeng
dc.publisherKoç University
dc.relation.collectionKoç University Theses & Dissertations Collection
dc.rightsrestrictedAccess
dc.rights.copyrightsnote© All Rights Reserved. Accessible to Koç University Affiliated Users Only!
dc.subjectProteins, Analysis
dc.subjectX-ray crystallography
dc.titleRoom-temperature apo structure of human SIRT2 solved by X-RAY crystallography and its application in targeted cancer drug development
dc.title.alternativeİnsan apo SIRT2 yapısının X-ışını kristalografisi ile oda sıcaklığında çözülmesi ve hedefe yönelik kanser ilaç geliştirilmesinde uygulanması
dc.typeThesis
dspace.entity.typePublication
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relation.isAdvisorOfThesis.latestForDiscovery05c2fe80-3c2e-4060-a2a2-59824658b8a9
relation.isParentOrgUnitOfPublication434c9663-2b11-4e66-9399-c863e2ebae43
relation.isParentOrgUnitOfPublication.latestForDiscovery434c9663-2b11-4e66-9399-c863e2ebae43

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