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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14288/3

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    Rationally reprogramming single-cell aging trajectories and lifespan through dynamic modulation of environmental inputs
    (Cell Press, 2024) Smart M.; Moreno DF; Acar, Murat; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine
    How do variations in nutrient levels influence cellular lifespan? A dynamical systems model of a core circuit involved in yeast aging suggests principles underlying lifespan extension observed at static and alternating glucose levels that are reminiscent of intermittent fasting regimens.