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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14288/3
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Publication Metadata only TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression(Elsevier, 2015) Şahin, Tuğce Demirtaş; Karson, Ayşe; Yazır, Yusufhan; Bayramgürler, Dilek; Utkan, Tijen; Department of Psychology; Balcı, Fuat; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 51269Previous findings have shown that patients with depression express higher levels of proinflammatory cytokines such as TNF-alpha and IL-6. We have recently found that Infliximab (a TNF-alpha inhibitor) decreased anhedonia and despair-like behavior in the rat unpredictable chronic mild stress (UCMS) model of depression suggesting that inflammation might play an important role in depression. An increasing number of studies suggest that inflammation is also associated with cognitive impairments. The current study aimed to investigate the effect of UCMS on the cognitive performance of rats and their hippocampal BDNF levels and the effect of chronic Infliximab (5 mg/kg/weekly, i.p.) treatment on these measures. Rats were subjected to different types of stressors daily for a period of 56 days to induce depression-like state. The UCMS resulted in impairments in spatial and emotional memory acquisition and retention with no effect on the level of locomotor activity. These behavioral effects of UCMS were accompanied by reduction in the level of BDNF in the CA1 and CA3 regions of the hippocampus. Chronic Infliximab treatment prevented the UCMS-induced cognitive impairments as well as the reduction in the levels of hippocampal brain-derived neurotrophic factor (BDNF). These results suggest that Infliximab improves the spatial and emotional memory impairments induced by chronic stress in rats likely through its effects on hippocampal function by modulating inflammation.Publication Metadata only Continuous spontaneous alternation and turn alternation in Artemia Sp.(The Regents of the University of California, 2015) Department of Psychology; Department of Psychology; Department of Psychology; Balcı, Fuat; Çarkoğlu, Can; Yılmaz, Meltem; Faculty Member; Undergraduate Student; Undergraduate Student; Department of Psychology; College of Social Sciences and Humanities; College of Social Sciences and Humanities; College of Social Sciences and Humanities; 51269; N/A; N/AFree-running spontaneous alternation refers to the animal's tendency to prefer the least recently visited locations in successive spatial choices, which is attributed to the animals' choice between stimuli based on prior experience. Turn alternation, which is observed in directional choices preceded by a forced turn in one direction, also reflects the animals' tendency to alternate between directional choices but this tendency has been assumed to rely on other cues (e.g., proprioceptive cues) derived from the prior responses (e.g., forced turn in one direction). Based on previous studies, the turn alternation appears to rely on more primitive (lower-form) information features and to be a more frequently observed empirical phenomenon than the spontaneous alternation. We investigated these two behavioral alternation tendencies in Artemia sp. Experiment 1 tested the continuous spontaneous alternation (cSAB) performance of Artemia sp. in two different mazes: t-maze (three options) and plus maze (four options). Experiment 2 tested the turn alternation performance of Artemia sp. counter-balancing the direction of initial forced-turn between subjects. Our results showed that Artemia sp. had nearly chance level spontaneous alternation performance in the t-maze and plus maze whereas a higher than chance level turn alternation performance. These results support the ubiquity of turn alternation tendency across species and point at the lack of spontaneous alternation in Artemia sp.Publication Metadata only Interval timing: stopping the internal stopwatch by photostimulation(Cell Press, 2017) Department of Psychology; Balcı, Fuat; Faculty Member; Department of Psychology; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); College of Social Sciences and Humanities; 51269Animals use estimates of time intervals to adaptively guide their anticipatory actions. New research on mice shows that photostimulation of the neural pathway that coordinates drinking behavior delays subsequent anticipatory responses by pausing/resetting the internal stopwatch.Publication Metadata only Intersectional stigmas are associated with lower viral suppression rates and antiretroviral therapy adherence among women living with HIV(Lippincott Williams and Wilkins (LWW), 2022) Pala, Andrea Norcini; Kempf, Mirjam-Colette; Konkle-Parker, Deborah; Wilson, Tracey E.; Tien, Phyllis C.; Wingood, Gina; Neilands, Torsten B.; Johnson, Mallory O.; Weiser, Sheri D.; Logie, Carmen H.; Turan, Janet M.; Department of Psychology; Turan, Bülent; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 219712Objectives: To explore the associations between intersectional poverty, HIV, sex, and racial stigma, adherence to antiretroviral therapy (ART), and viral suppression among women with HIV (WHIV). Design: We examined intersectional stigmas, self-report ART adherence, and viral suppression using cross-sectional data. Methods: Participants were WHIV (N = 459) in the Women's Adherence and Visit Engagement, a Women's Interagency HIV Study substudy. We used Multidimensional Latent Class Item Response Theory and Bayesian models to analyze intersectional stigmas and viral load adjusting for sociodemographic and clinical covariates. Results: We identified five intersectional stigma-based latent classes. The likelihood of viral suppression was approximately 90% lower among WHIV who experienced higher levels of poverty, sex, and racial stigma or higher levels of all intersectional stigmas compared with WHIV who reported lower experiences of intersectional stigmas. ART adherence accounted for but did not fully mediate some of the associations between latent intersectional stigma classes and viral load. Conclusion: The negative impact of intersectional stigmas on viral suppression is likely mediated, but not fully explained, by reduced ART adherence. We discuss the research and clinical implications of our findings.Publication Metadata only Lists as alternative discourse structures to narratives in preschool children's conversations(Taylor & Francis, 2004) N/A; Department of Psychology; Küntay, Aylin C.; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 178879This study examines a corpus of conversations of Turkish preschool-age children with adults, with the goal of analyzing 2 types of extended discourse structures (i.e., lists and narratives). Lists and narratives are compared with respect to (a) their internal structures, and (b) their social functions in the participants' daily interactions. The analyses suggest that although lists and narratives differ on structural grounds, they overlap in the functions they serve for the tellers. Lists constitute more of a descriptive structure, although temporality is foregrounded in narratives. Yet, both genres are used to express strips of past experience, and are employed by the same child in similar contexts, framed by similar metadiscourse comments, often blending into another. These findings suggest that, although lists and narratives are revealed as 2 clearly differentiable genres on formal analyses, lists carry some features of narrativity in children's conversational interactions.Publication Metadata only Cross-cultural industrial and organizational psychology - contributions, past developments, and future directions(Sage, 2000) Department of Psychology; Aycan, Zeynep; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 5798This article aims at critically evaluating the; theory and scope of cross-cultural industrial and organizational (I/O) research, emphasizing its past and its future. In the theory section, the author discusses the ways sociocultural context influences organizational phenomena. Also discussed are issues such as the level of theory, assumption of linearity, unilateral effect of culture on organizations, conceptualization of culture, and atheoretical nature of research. In the second section, three areas of research, which are underrepresented in cross-cultural I/O literature, are discussed: staffing, performance management, and employee health and safety. It is argued that compared to traditional research topics of cross-cultural I/O psychology (e.g., leadership, motivation, work values, etc.), these topics are more central to the field, more related to improvement of human potential and conditions at work, and better able to guide practices in various cultural contexts.Publication Metadata only Why wait for the verb? Turkish speaking children use case markers for incremental language comprehension(Elsevier, 2019) Özge, Duygu; Snedeker, Jesse; Department of Psychology; Küntay, Aylin C.; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 178879Publication Metadata only Eyewitness memory distortion following co-witness discussion: a replication of Garry, French, Kinzett, and Mori (2008) in ten countries(AMER PSYCHOLOGICAL ASSOC, 2019) Ito, Hiroshi; Barzykowski, Krystian; Grzesik, Magdalena; Janssen, Steve M. J.; Khor, Jessie; Rowthorn, Harriet; Wade, Kimberley A.; Luna, Karlos; Albuquerque, Pedro B.; Kumar, Devvarta; Singh, Arman Deep; Cecconello, William Weber; Cadavid, Sara; Laird, Nicole C.; Baldassari, Mario J.; Lindsay, D. Stephen; Mori, Kazuo; Department of Psychology; N/A; Gülgöz, Sami; Gürdere, Ceren; Faculty Member; PhD Student; Department of Psychology; N/A; College of Social Sciences and Humanities; Graduate School of Social Sciences and Humanities; N/A; 49200; N/AWe examined the replicability of the co-witness suggestibility effect originally reported by Garry et al. (2008) by testing participants from 10 countries (Brazil, Canada, Colombia, India, Japan, Malaysia, Poland, Portugal, Turkey, and the United Kingdom; total N=486). Pairs of participants sat beside each other, viewing different versions of the same movie while believing that they viewed the same version. Later, participant pairs answered questions collaboratively, which guided them to discuss conflicting details. Finally, participants took a recognition test individually. Each of the 10 samples replicated the Garry et al. finding: Participants often reported on the final test a non-witnessed answer that their co-witness had stated during the collaboration phase. Such co-witness suggestibility errors were especially likely when the witness had not disputed the co-witness's report during the collaboration phase. The results demonstrate the replicability and generalizability of the co-witness suggestibility effect.Publication Metadata only Second language tutoring using social robots: a large-scale study(Institute of Electrical and Electronics Engineers (IEEE), 2019) Vogt, Paul; van den Berghe, Rianne; de Haas, Mirjam; Hoffman, Laura; Montanier, Jean-Marc; Oudgenoeg-Paz, Ora; Garcia, Daniel Hernandez; Papadopoulos, Fotios; Schodde, Thorsten; Verhagen, Josje; Wallbridge, Christopher D.; Willemsen, Bram; de Wit, Jan; Belpaeme, Tony; Kopp, Stefan; Krahmer, Emiel; Leseman, Paul; Pandey, Amit Kumar; Department of Psychology; Department of Psychology; Department of Psychology; Department of Psychology; Department of Psychology; Göksun, Tilbe; Kanero, Junko; Küntay, Aylin C.; Mamuş, Ayşe Ezgi; Oranç, Cansu; Faculty Member; Researcher; Faculty Member; Researcher; Researcher; Department of Psychology; College of Social Sciences and Humanities; College of Social Sciences and Humanities; College of Social Sciences and Humanities; College of Social Sciences and Humanities; College of Social Sciences and Humanities; 47278; N/A; 178879; N/A; N/AWe present a large-scale study of a series of seven lessons designed to help young children learn English vocabulary as a foreign language using a social robot. The experiment was designed to investigate 1) the effectiveness of a social robot teaching children new words over the course of multiple interactions (supported by a tablet), 2) the added benefit of a robot's iconic gestures on word learning and retention, and 3) the effect of learning from a robot tutor accompanied by a tablet versus learning from a tablet application alone. For reasons of transparency, the research questions, hypotheses and methods were preregistered. With a sample size of 194 children, our study was statistically well-powered. Our findings demonstrate that children are able to acquire and retain English vocabulary words taught by a robot tutor to a similar extent as when they are taught by a tablet application. In addition, we found no beneficial effect of a robot's iconic gestures on learning gains.Publication Metadata only What keeps teachers engaged during professional development? The role of interest development(Multidisciplinary Digital Publishing Institute (MDPI), 2023) Akcaoglu, Mete; Dogan, Selcuk; Department of Psychology; Özcan, Meryem Şeyda; Teaching Faculty; Department of Psychology; College of Social Sciences and Humanities; N/AInterest influences adults' and young learners' learning in formal and informal contexts. Although interest and interest development frameworks have been used in research on student-learning, they are not used in teacher-focused research, especially as "outcomes" of teacher professional development (PD) activities. In this study, we used interest development as the outcome of PD in computer science (CS) and investigated the factors that influenced teachers' (n = 5) interest development toward CS using various data sources and analysis methods. We found that interest development is (a) varied, (b) influenced by self-relation, knowledge, and affect, (c) associated with reengagement with PD activities, and (d) it can be captured using computational text analysis methods and online log data.