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    How does poverty stigma affect depression symptoms for women living with HIV? longitudinal mediating and moderating mechanisms
    (Springer, 2023) Kempf, Mirjam-Colette; Konkle-Parker, Deborah; Wilson, Tracey E.; Tien, Phyllis C.; Wingood, Gina; Neilands, Torsten B.; Johnson, Mallory O.; Logie, Carmen H.; Weiser, Sheri D.; Department of Psychology; Turan, Bülent; Turan, Janet Molzan; Department of Psychology; College of Social Sciences and Humanities; School of Medicine
    In a sample of women living with HIV, we examined whether individual traits fear of negative evaluation and resilience moderate the internalization of poverty stigma that these women experience from others. We also examined the downstream effects of these processes on depression symptoms using moderated serial mediation analyses. Data were collected annually for 4 years (2016-2020; T1, T2, T3, and T4) from 369 women living with HIV at 4 US cities using validated measures. Moderation effects were evaluated examining simple slopes at one standard deviation above and below the mean of the moderator. In all mediation analyses utilizing bootstrapping, we used the independent variable measured at T1, the mediators measured at subsequent visits (T2 and T3), and the outcome at the last visit (T4) to preserve the temporal sequence among the independent variable, mediators, and outcome variable. We also adjusted for T1 values of all mediators and outcome variables in analyses. Women with stronger fears of negative evaluation by others or lower dispositional resilience had stronger associations between experienced poverty stigma and internalized poverty stigma. Internalized poverty stigma (T2) mediated the association between experienced poverty stigma (T1) and depression symptoms (T4); this mediated association was moderated by fear of negative evaluation and resilience (T1). Finally, internalized poverty stigma (T2) and avoidance coping (T3) were serial mediators in the association between experienced poverty stigma (T1) and depression symptoms (T4), moderated by fear of negative evaluation and resilience. Understanding factors that minimize internalization of stigma and buffer its negative effects on mental health can inform interventions to improve health outcomes of individuals with stigmatized conditions.
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    T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV
    (Elsevier, 2022) Williams, Dionna W.; Flores, Bianca R.; Xu, Yanxun; Wang, Yuezhe; Yu, Danyang; Peters, Brandilyn A.; Adedimeji, Adebola; Wilson, Tracey E.; Merenstein, Daniel; Tien, Phyllis C.; Cohen, Mardge H.; Weber, Kathleen M.; Adimora, Adaora A.; Ofotokun, Igho; Fischl, Margaret; Turan, Janet; Laumet, Geoffroy; Landay, Alan L.; Dastgheyb, Raha M.; Gange, Stephen J.; Weiser, Sheri D.; Rubin, Leah H.; Department of Psychology; Turan, Bülent; Department of Psychology; College of Social Sciences and Humanities
    Neuropsychiatric complications are common among women with HIV (WWH). The pathophysiological mechanisms underlying these complications are not fully known but likely driven in part by immune modulation. We examined associations between T-cell activation states which are required to mount an effective immune response (activation, co-stimulation/normal function, exhaustion, senescence) and neuropsychiatric complications in WWH. 369 WWH (78% HIV RNA undetectable/<20cp/mL) enrolled in the Women's Interagency HIV Study completed neuropsychological testing and measures of depression (Center for Epidemiological Studies Depression Scale-CES-D), self-reported stress levels (Perceived Stress Scale-10), and post-traumatic stress (PTSD Checklist-Civilian Scale). Multiparametric flow cytometry evaluated T-cell activation state. Partial least squares regressions were used to examine T-cell phenotypes and neuropsychiatric outcome associations after confounder adjustment. In the total sample and among virally suppressed (VS)-WWH, CD4(+) T-cell exhaustion was associated with poorer learning and attention/working memory (P's < 0.05). In the total sample, CD4(+) T-cell activation was associated with better attention/working memory and CD8(+) T-cell co-stimulation and senescence was associated with poorer executive function (P's < 0.05). For mental health outcomes, in the total sample, CD4(+) T-cell activation was associated with more perceived stress and CD4(+) T-cell exhaustion was associated with less depressive symptoms (P's < 0.05). Among VS-WWH, CD4(+) senescence was associated with less perceive stress and CD8(+) T-cell co-stimulation and senescence was associated with higher depression (P's < 0.05). Together, results suggest the contribution of peripheral CD4(+) and CD8(+) T-cell activation status to neuropsychiatric complications in WWH.
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    Mental health and support 1 year after the earthquakes in Türkiye
    (Elsevier Ltd, 2024) Kurt, Gulsah; Erşahin, Merve; Aker, A Tamer; Uygun, Ersin; Department of Psychology; Acartürk, Ceren; Department of Psychology; College of Social Sciences and Humanities
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    An examination of the mediating role of maladaptive emotion regulation strategies in the complex relationship between interpersonal needs and suicidal behavior
    (Frontiers Media Sa, 2024) Bakhshesh-Boroujeni, Michael; Farajpour-Niri, Sepideh; Hekmati, Issa; Asgarabad, Mojtaba Habibi; Department of Psychology; Eskin, Mehmet; Department of Psychology; Graduate School of Social Sciences and Humanities; College of Social Sciences and Humanities
    Background: Studies have shown that psychological factors, notably interpersonal needs and emotion regulation, play a significant role in suicidal behavior. Interpersonal needs are significant contextual components that affect emotion regulation and contribute to a wide range of dysfunctional behaviors, such as suicidal behavior. It has been postulated that emotion regulation mediates the associations between proximal and distal risk factors of suicidal behavior. Method: The sample consisted of 340 community-dwelling individuals (62.5% women;SD = 0.48) with an age range of 18 through 55 (M = 30.23;SD = 8.54) who completed the interpersonal needs questionnaire, the suicide behaviors questionnaire-revised, and the cognitive emotion regulation questionnaire. The Structural Equation Modeling (SEM) approach was utilized to evaluate a mediation model. Results: The findings indicate that interpersonal needs (i.e., perceived burdensomeness r = .55, p <.01 and thwarted belongingness r = .25, p <.01) and putatively maladaptive cognitive emotion regulation strategies (i.e., self-blame;r = .38, p <.01, catastrophizing;r = .55, p <.01, rumination;r = .40, p <.01, and other blame;r = .44, p <.01) have strong associations with suicidal behavior, and these strategies have a mediating effect on the association between interpersonal needs and suicidal behavior. Conclusions: Our findings show that contextual-interpersonal needs, which underpin suicidal behavior, are significantly influenced by maladaptive emotional processes. Thus, therapeutic outcomes might be enhanced by focusing on the content of the associated cognitions and trying to reduce maladaptive regulatory processes like rumination and catastrophization.
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    Effect of trauma on asylum seekers and refugees receiving a WHO psychological intervention: a mediation model
    (TAYLOR & FRANCIS LTD, 2024) Serra, Riccardo; Purgato, Marianna; Tedeschi, Federico; Karyotaki, Eirini; Uygun, Ersin; Turrini, Giulia; Winkler, Hildegard; Pinucci, Irene; Wancata, Johannes; Walker, Lauren; Popa, Mariana; Sijbrandij, Marit; Valimaki, Maritta; Koesters, Markus; Nose, Michela; Anttila, Minna; Churchill, Rachel; White, Ross G.; Lantta, Tella; Klein, Thomas; Wochele-Thoma, Thomas; Tarsitani, Lorenzo; Barbui, Corrado; Department of Psychology; Acartürk, Ceren; Department of Psychology; College of Social Sciences and Humanities
    Background: Scalable psychological interventions such as the WHO's Self-Help Plus (SH+) have been developed for clinical and non-clinical populations in need of psychological support. SH+ has been successfully implemented to prevent common mental disorders among asylum seekers and refugees who are growing in number due to increasing levels of forced migration. These populations are often exposed to multiple, severe sources of traumatisation, and evidence of the effect of such events on treatment is insufficient, especially for non-clinical populations.Objective: We aim to study the effect of potentially traumatic experiences (PTEs) and the mediating role of symptoms of posttraumatic stress disorder (PTSD) on the improvement following SH+.Method: Participants allocated to SH+ who received at least three sessions (N = 345) were extracted from two large, randomised, European prevention trials involving asylum seekers and refugees. Measures of distress, depression, functional impairment, and post-traumatic stress symptoms were administered at baseline and 6 months post-intervention, together with measures of well-being and quality of life. Adjusted models were constructed to examine the effect of PTEs on post-intervention improvement. The possible mediating role of PTSD symptoms in this relationship was then tested.Results: Increasing numbers of PTEs decreased the beneficial effect of SH+ for all measures. This relationship was mediated by symptoms of PTSD when analysing measures of well-being and quality of life. However, this did not apply for measures of mental health problems.Conclusions: Exposure to PTEs may largely reduce benefits from SH+. PTSD symptomatology plays a specific, mediating role on psychological well-being and quality of life of participants who experienced PTE. Healthcare professionals and researchers should consider the role of PTEs and PTSD symptoms in the treatment of migrants and refugees and explore possible feasible add-on solutions for cases exposed to multiple PTEs. Increasing numbers of potentially traumatic experiences can decrease the beneficial effect of a manualized group psychotherapeutic intervention in migrants and refugees across multiple countries.In absence of a full threshold diagnosis of post-traumatic stress disorder, post-traumatic stress symptoms still mediate the relation between potentially traumatic experiences and some outcome improvements at follow-up.While the moderating role of number of potentially traumatic experiences applies to all outcomes (depression symptoms, psychological distress, functional impairment, well-being, and quality of life), the mediating role of post-traumatic stress symptoms in this relation only applies to well-being and quality of life. Antecedentes: Se han desarrollado intervenciones psicol & oacute;gicas escalables, como Self-Help Plus (SH+) de la OMS, para poblaciones cl & iacute;nicas y no cl & iacute;nicas que necesitan apoyo psicol & oacute;gico. SH+ se ha implementado con & eacute;xito para prevenir trastornos mentales frecuentes entre los solicitantes de asilo y refugiados, cuyo n & uacute;mero est & aacute; aumentando debido a los crecientes niveles de migraci & oacute;n forzada. Estas poblaciones a menudo est & aacute;n expuestas a m & uacute;ltiples y graves fuentes de traumatizaci & oacute;n, y la evidencia del efecto de tales eventos en el tratamiento es insuficiente, especialmente para las poblaciones no cl & iacute;nicas.Objetivo: Nuestro objetivo es estudiar el efecto de las experiencias potencialmente traum & aacute;ticas (EPTs) y el papel mediador de los s & iacute;ntomas del trastorno de estr & eacute;s postraum & aacute;tico (TEPT) en la mejora despu & eacute;s de SH+.M & eacute;todo: Los participantes asignados al programa de intervenci & oacute;n SH+ que recibieron al menos tres sesiones (N = 345) fueron extra & iacute;dos de dos grandes ensayos de prevenci & oacute;n europeos, aleatorizados, que involucraron a personas que solicitaron asilo y refugiados. Se administraron medidas de angustia, depresi & oacute;n, deterioro funcional y s & iacute;ntomas de estr & eacute;s postraum & aacute;tico al inicio del estudio y 6 meses despu & eacute;s de la intervenci & oacute;n, junto con medidas de bienestar y calidad de vida. Se construyeron modelos ajustados para examinar el efecto de las EPTs en la mejora posterior a la intervenci & oacute;n. A continuaci & oacute;n se comprob & oacute; el posible papel mediador de los s & iacute;ntomas del trastorno de estr & eacute;s postraum & aacute;tico en esta relaci & oacute;n.Resultados: Un n & uacute;mero creciente de EPTs disminuy & oacute; el efecto beneficioso de SH+ para todas las medidas. Esta relaci & oacute;n estuvo mediada por los s & iacute;ntomas del TEPT al analizar medidas de bienestar y calidad de vida. Sin embargo, esto no se aplica a las medidas de problemas de salud mental.Conclusiones: La exposici & oacute;n a EPTs puede reducir en gran medida los beneficios de SH+. La sintomatolog & iacute;a TEPT desempe & ntilde;a un papel mediador espec & iacute;fico en el bienestar psicol & oacute;gico y la calidad de vida de los participantes que experimentaron EPTs. Los profesionales de la salud y los investigadores deben considerar el papel de las EPTs y los s & iacute;ntomas de TEPT en el tratamiento de migrantes y refugiados, y explorar posibles soluciones factibles complementarias para los casos expuestos a m & uacute;ltiples EPTs.
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    Inequality on the frontline: a multi-country study on gender differences in mental health among healthcare workers during the Covid-19 pandemic
    (Cambridge University Press, 2024) Czepiel, Diana; Mccormack, Clare; da Silva, Andrea T. C.; Seblova, Dominika; Moro, Maria F.; Restrepo-Henao, Alexandra; Martinez, Adriana M.; Afolabi, Oyeyemi; Alnasser, Lubna; Alvarado, Ruben; Asaoka, Hiroki; Ayinde, Olatunde; Balalian, Arin; Ballester, Dinarte; Barathie, Josleen A. l.; Basagoitia, Armando; Basic, Djordje; Burrone, Maria S.; Carta, Mauro G.; Durand-Arias, Sol; Fernandez-Jimenez, Eduardo; Frey, Marcela I. F.; Gureje, Oye; Isahakyan, Anna; Jaldo, Rodrigo; Karam, Elie G.; Khattech, Dorra; Lindert, Jutta; Martinez-Ales, Gonzalo; Mascayano, Franco; Mediavilla, Roberto; Gonzalez, Javier A. Narvaez; Nasser-Karam, Aimee; Nishi, Daisuke; Olaopa, Olusegun; Ouali, Uta; Puac-Polanco, Victor; Ramirez, Dorian E.; Ramirez, Jorge; Rivera-Segarra, Eliut; Rutten, Bart P. F.; Santaella-Tenorio, Julian; Sapag, Jaime C.; Seblova, Jana; Soto, Maria T. S.; Tavares-Cavalcanti, Maria; Valeri, Linda; Sijbrandij, Marit; Susser, Ezra S.; Hoek, Hans W.; van der Ven, Els; Department of Psychology; Eskin, Mehmet; Department of Psychology; College of Social Sciences and Humanities
    Healthcare workers (HCWs) were at increased risk for mental health problems during the COVID-19 pandemic, with prior data suggesting women may be particularly vulnerable. Our global mental health study aimed to examine factors associated with gender differences in psychological distress and depressive symptoms among HCWs during COVID-19. Across 22 countries in South America, Europe, Asia and Africa, 32,410 HCWs participated in the COVID-19 HEalth caRe wOrkErS (HEROES) study between March 2020 and February 2021. They completed the General Health Questionnaire-12, the Patient Health Questionnaire-9 and questions about pandemic-relevant exposures. Consistently across countries, women reported elevated mental health problems compared to men. Women also reported increased COVID-19-relevant stressors, including insufficient personal protective equipment and less support from colleagues, while men reported increased contact with COVID-19 patients. At the country level, HCWs in countries with higher gender inequality reported less mental health problems. Higher COVID-19 mortality rates were associated with increased psychological distress merely among women. Our findings suggest that among HCWs, women may have been disproportionately exposed to COVID-19-relevant stressors at the individual and country level. This highlights the importance of considering gender in emergency response efforts to safeguard women's well-being and ensure healthcare system preparedness during future public health crises.
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    Looming cognitive style (LCS), repetitive negative thinking (RNT), and anxiety: a cross-sectional study
    (Springer International Publishing Ag, 2018) Department of Psychology; Atalay, Ayşe Altan; Teaching Faculty; Department of Psychology; College of Social Sciences and Humanities; 205807
    Looming cognitive style (LCS) was proposed as a vulnerability and risk factor specific for anxiety disorders, which manifests itself through the overestimation of threat perception, as becoming more intense through space and time. Despite a large number of studies on the association of LCS with anxiety disorders, research on the mechanisms through which LCS influence anxiety are rather limited. Worry and rumination, on the other hand, are disorder-specific types of repetitive negative thinking (RNT), which is a transdiagnostic risk factor associated with different forms of psychological disorders including anxiety disorders. The mediator roles of worry and rumination, as two disorder-specific types of RNT, in the relationship of LCS with anxiety and depression are examined in the present study. Participants were 333 university students (243 female) with the mean age of 20.98 (SD=2.45). Participants were administered scales assessing LCS, disorder-specific repetitive negative thinking, anxiety, and depression. Results showed that both worry and brooding mediate the relationship of LCS with anxiety. But, although the mediating role of worry is attenuated, effect of brooding disappeared, when depression is controlled. Building on the previous studies, the results indicate that LCS is a vulnerability factor directly related to anxiety rather than depression. The reverse model based on the cascade model suggesting that worry is one of the mechanisms that is likely to explain the relationship between anxiety and LCS was not supported. Further, longitudinal research is required to obtain more clear results.
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    Social support and resilience among Syrian refugees: The mediating role of self-efficacy
    (Routledge Journals, Taylor & Francis Ltd, 2023) Pak, Sukufe; Yurtbakan, Taylan; Department of Psychology; Acartürk, Ceren; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 39271
    Refugees are exposed to potentially traumatic events before, during, and after the forced displacement. Related to these events, they are at risk of developing mental health problems. From a public-health perspective, it is important to investigate factors fostering resilience among refugee population. This study aimed to explore the mediation role of self-efficacy between social support and resilience among Syrian refugees living in Istanbul, Turkey. A cross-sectional survey of 339 Syrian refugees aged 18 and older was conducted between September 2018 and March 2019 in Istanbul. The Connor-Davidson Resilience Scale (CD-RISC) was used to measure resilience, the Multidimensional Scale of Perceived Social Support (MSPSS) assessed social support, and self-efficacy was measured by the General Self-Efficacy Scale (GSE). The simple mediation model analysis showed the mediating effect of self-efficacy on the social support and resilience relationship. Among the demographic factors, males and individuals with higher education levels reported increased resilience. Findings illuminated the importance of self-efficacy in promoting resilience among refugee population. Implications were discussed in a culturally appropriate way to enhance self-efficacy among Syrian refugees.
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    The role of socioeconomic adversity and armed confict in executive function, theory of mind and empathy in children
    (Springer, 2021) Kara, Buket; Department of Psychology; Selçuk, Bilge; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 52913
    This study investigates the role of socioeconomic adversity and armed conflict in executive function (EF), theory of mind (ToM) and empathy in a rarely studied group, children living in eastern Turkey. The data were collected from 115 children (60 girls) aged 39 to 95 months (M = 68.22, SD = 14.62). Results revealed that children's performance was low in the EF and ToM tasks, and high in the empathy task. In path analysis, controlling for age, armed conflict experience predicted lower EF (beta = - 0.15) and higher empathy (beta = 0.21), and socioeconomic adversity predicted lower ToM (beta = 0.20). These findings contribute to our knowledge on cognitive and emotional development of children who live in such disadvantaged contexts.
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    An investigation of the psychometric properties of the Turkish versions of the interpersonal needs questionnaire and acquired capability for suicide-fearlessness about death scale
    (2020) Arslantaş, Hülya; Öztürk, Cennet Şafak; Eskin, Berke; Department of Psychology; Eskin, Mehmet; Faculty Member; Department of Psychology; College of Social Sciences and Humanities; 2210
    Objective: Suicidal behavior is serious public health problem. Interpersonal Psychological Theory of SuicideIPT tells that feelings of thwarted belongingness and perceived burden someness are composed of two perceptions that make people tend to suicide. But the theory argues that will is not sufficient for occurrence of a suicidal behaviour. Individual must have acquired capability for suicide as well. Recently it is seen that IPT is a theorethical framework that is frequently used in suicide researches. The purpose of this study was to investigate the psychometric properties of the Turkish versions of the Interpersonal Needs Questionnaire (INQ) and Acquired Capability for Suicide Scale -Fearlessness about Death (ACSS-FAD). Method: Data were collected from 409 university students. Results: The Turkish Interpersonal Needs Questionnaire and the Acquired Capability for Suicide- Fearlessness about Death scale demonstrated adequate psychometric properties. Both had high internal consistency and test-retest reliabilities. Discussion: The results of the present study have revealed that the Turkish versions of the Interpersonal Needs Questionnaire (INQ) and Acquired Capability for Suicide Scale-Fearlessness about Death (ACSS-FAD) are reliable and valid instruments for measuring the constructs of the Interpersonal Psychological Theory of suicide. Therefore, we conclude that the two measuring instruments may contribute to the suicidological research and clinical practice in Turkey. / Öz: Amaç: Günümüzde düşünce, girişim ve ölümleri kapsayan intihar davranışları önemli bir halk sağlığı sorunu haline gelmiştir. Kişilerarası Psikolojik İntihar Kuramı (KPİK) engellenmiş ait olma (thwarted belongingness) ve başkalarına yük olma (perceived burden someness) duygularının insanları intihara meyilli/istekli hale getiren iki algıdan oluştuğundan bahsetmektedir. Fakat kuram, bir intihar davranışının ortaya çıkması için isteğin yeterli olmadığını bunun için kişide edinilmiş intihar yeterliliğinin (acquired capability for suicide) de olması gerektiğini öne sürmektedir. Son zamanlarda KPİK'nın intiharbilim alanındaki araştırmalarda sık kullanılan bir kuramsal çerçeve haline geldiği görülmektedir. Bu çalışmanın amacı kişilerarası psikolojik intihar kuramının yapısal kavramları olan Kişilerarası İhtiyaçlar Anketi (KİA) ve Edinilmiş İntihar Yeterliliği-Ölüm Korkusuzluğu Ölçeğinin (EİY-ÖKÖ) Türkçelerinin psikometrik özelliklerini araştırmaktır. Yöntem: Bu çalışmanın verileri üniversitelerin değişik akademik programlarında öğrenim görmekte olan 409 üniversite öğrencisinden toplanmıştır. Bulgular: Kişilerarası İhtiyaçlar Anketi ve Edinilmiş İntihar Yeterliliği-Ölüm Korkusuzluğu Ölçeğinin Türkçe formunun psikometrik özelliklerinin yeterli düzeyde olduğu bulunmuştur. Söz konusu ölçüm araçlarının iç-tutarlık ve test-tekrar test güvenirliklerinin yeterli olduğu görülmüştür. Sonuç: Bu çalışmadan elde edilen bulgular Kişilerarası İhtiyaçlar Anketi ve Edinilmiş İntihar Yeterliliği-Ölüm Korkusuzluğu Ölçeğinin Türkçesi için geçerli ve güvenilir ölçümler sağlamıştır. Söz konusu ölçüm aracı Türkiye’deki intiharbilim araştırmalarına ve klinik uygulamalara önemli katkı sağlayacaktır.