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Permanent URI for this communityhttps://hdl.handle.net/20.500.14288/2

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    Frequency-domain model of microfluidic molecular communication channels with graphene BioFET-based receivers
    (Institute of Electrical and Electronics Engineers Inc., 2024) Department of Electrical and Electronics Engineering; Kuşcu, Murat; Abdalı, Ali; Department of Electrical and Electronics Engineering; College of Engineering; Graduate School of Sciences and Engineering
    Molecular Communication (MC) is a bio-inspired communication paradigm utilizing molecules for information transfer. Research on MC has largely transitioned from theoretical investigations to practical testbed implementations, harnessing microfluidics and sensor technologies. Accurate models for input-output relationships on these platforms are crucial for optimizing MC methods and understanding the impact of physical parameters on performance. Our study focuses on a practical microfluidic MC system with a graphene field effect transistor biosensor (bioFET)-based receiver, developing an end-to-end frequency-domain model. The model provides insights into the dispersion, distortion, and attenuation of received signals, thus potentially informing the design of new frequency-domain MC techniques, such as modulation and detection methods. The accuracy of the developed model is verified through particle-based spatial stochastic simulations of pulse transmission and ligand-receptor reactions on the receiver surface.
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    Microfluidic molecular communication transmitter based on hydrodynamic gating
    (IEEE-Inst Electrical Electronics Engineers Inc, 2024)  ; Department of Electrical and Electronics Engineering; Bolhassan, Iman Mokari; Abdalı, Ali; Department of Electrical and Electronics Engineering;  ; Graduate School of Sciences and Engineering; College of Engineering;  
    Molecular Communications (MC) is a bio-inspired paradigm for transmitting information using chemical signals, which can enable novel applications at the junction of biotechnology, nanotechnology, and information and communication technologies. However, designing efficient and reliable MC systems poses significant challenges due to the complex nature of the physical channel and the limitations of the micro/nanoscale transmitter and receiver devices. In this paper, we propose a practical microfluidic transmitter architecture for MC based on hydrodynamic gating, a widely utilized technique for generating chemical waveforms in microfluidic channels with high spatiotemporal resolution. We develop an approximate analytical model that can capture the fundamental characteristics of the generated molecular pulses, such as pulse width, pulse amplitude, and pulse delay, as functions of main system parameters, such as flow velocity and gating duration. We validate the accuracy of our model by comparing it with finite element simulations using COMSOL Multiphysics under various system settings. Our analytical model can enable the optimization of microfluidic transmitters for MC applications in terms of minimizing intersymbol interference and maximizing data transmission rate.