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Publication Open Access A clinical scoring system to predict the development of bronchopulmonary dysplasia(Thieme Medical Publishers, 2015) Hayran, Mutlu; Derin, Hatice; Ovalı, Fahri; N/A; Gürsoy, Tuğba; Faculty Member; School of Medicine; 214691Objective: This study aims to develop a scoring system for the prediction of bronchopulmonary dysplasia (BPD). Methods: Medical records of 652 infants whose gestational age and birth weight were below 32 weeks and 1,500g, respectively, and who survived beyond 28th postnatal day were reviewed retrospectively. Logistic regression methods were used to determine the clinical and demographic risk factors within the first 72 hours of life associated with BPD, as well as the weights of these factors on developing BPD. Predictive accuracy of the scoring system was tested prospectively at the same unit. ResultsBirth weight, gestational age, gender, presence of respiratory distress syndrome, patent ductus arteriosus, intraventricular hemorrhage, hypotension were the most important risk factors for BPD. Therefore, a scoring system (BPD-TM score) ranging from 0 to 13 and grouped in four tiers (0-3: low, 4-6: low intermediate, 7-9: high intermediate, and 10-13: high risk) was developed based on these factors. Below the score of 4, 4.1% of infants (18/436), above the score of 9, 100% (29/29) of the infants developed BPD. The score was validated successfully in 172 infants. Conclusion: With this easy to use scoring system, one can predict the neonate at risk for BPD at 72 hours of life and direct preventive measures toward these infants.
Publication Metadata only A deep breath for the mothers of dissabled children(Springer, 2016) N/A; N/A; Ocakçı, Ayşe Ferda; Faculty Member; School of Nursing; 1729N/APublication Metadata only A rare cause of chronic hyponatremia in an infant: answers(Springer, 2020) Güran, T.; N/A; Yeşiltepe Mutlu, Rahime Gül; Taşdemir, Mehmet; Kızılkan, Nuray Uslu; Hatun, Şükrü; Kayserili, Hülya; Bilge, İlmay; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 153511; 175867; 221274; 153504; 7945; 198907N/APublication Metadata only A rare cause of chronic hyponatremia in an infant: questions(Springer, 2020) Guran, Tulay; N/A; Yeşiltepe Mutlu, Rahime Gül; Taşdemir, Mehmet; Kızılkan, Nuray Uslu; Hatun, Şükrü; Kayserili, Hülya; Bilge, İlmay; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 153511; 175867; 221274; 153504; 7945; 198907N/APublication Metadata only A rare complication after an interventional procedure using the common carotid: carotid pseudoaneurysm in an infant(Cambridge University Press (CUP), 2023) N/A; Biçer, Mehmet; Kızılkaya, Mete Han; Ödemiş, Ender; Gündoğmuş, Cemal Aydin; Faculty Member; Doctor; Faculty Member; Doctor; School of Medicine; N/A; School of Medicine; N/A; Koç University Hospital; 310599; N/A; 194545; N/AThe carotid artery is a valuable vascular access that can be used in patients who have undergone repetitive interventional and surgical procedures and premature babies. In the past, cut-down was used but nowadays, mostly the procedure is performed under ultrasonographic guidance. Complications such as bleeding, haematoma, and pseudoaneurysm may occur when the carotid artery is used as a vascular access for the procedures such as aortic balloon valvuloplasty, coarctation balloon angioplasty, or after interventional or surgical treatments to the carotid artery. Although pseudoaneurysm is very rare, prompt diagnosis and accurate treatment planning are life-saving. In this article, the diagnosis and treatment of pseudoaneurysm in the left common carotid after transcatheter coarctation balloon angioplasty in a 6-month-old infant will be presented.Publication Metadata only A Turkish girl with H syndrome: stunted growth and development of autoimmune insulin dependent diabetes mellitus in the 6th year of diagnosis(Walter De Gruyter Gmbh, 2019) N/A; N/A; Özlü, Can; Yeşiltepe Mutlu, Rahime Gül; Hatun, Şükrü; Undergraduate Student; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; N/A; Koç University Hospital; Koç University Hospital; N/A; 153511; 153504Background: H syndrome ([0MIM] 602782) is an autosomal recessive disorder with systemic manifestations and characteristic skin lesions, caused by mutations of the SLC29A3 gene. Short stature and diabetes mellitus are the major endocrine problems related to H syndrome, however, clear data from clinical follow-up of H syndrome patients is lacking in the literature. Case presentation: Here, we present follow-up of a Turkish girl diagnosed with H syndrome at the age of 10 with a homozygous 310(c.933T> A, p.C310X) early stop codon mutation on exon 6 of the SLC29A3 gene. She had severe short stature non-responsive to growth hormone (GH) treatment and gluten-free diet despite low GH levels and celiac antibody positivity. She developed insulin dependent diabetes mellitus (IDDM) symptoms 6 years after the initial diagnosis. Conclusions: H syndrome patients can develop IDDM years after characteristic symptoms. Short stature in H syndrome patients may not respond to GH replacement or gluten-free diet alone.Publication Open Access Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review(BioMed Central, 2016) Dhami, S.; Nurmatov, U.; Pajno, G. B.; Fernandez-Rivas, M.; Muraro, A.; Roberts, G.; Akdiş, C.; Alvaro-Lozano, M.; Beyer, K.; Bindslev-Jensen, C.; Burks, W.; du Toit, G.; Ebisawa, M.; Eigenmann, P.; Knol, E.; Makela, M.; Nadeau, K. C.; O'Mahony, L.; Papadopoulos, N.; Poulsen, L.; Sampson, H.; Santos, A.; van Ree, R.; Timmermans, F.; Sheikh, A.; N/A; Saçkesen, Cansın; Faculty Member; School of Medicine; 182537Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.Publication Metadata only Ambulatory blood pressure correlates with MRI-based renal volume in children and adolescents with autosomal dominant polycystic kidney disease(Springer, 2022) Yilmaz, Kubra; Saygili, Seha; Akgun-dogan, Ozlem; Yildirim, Zeynep Nagehan Yuruk; Cicek, Rumeysa Yasemin; Oner, Huseyin Adil; Aksu, Bagdagul; Akyel, Nazli Gulsum; Oguzhan, Ozge; Dursun, Hasan; Yavuz, Sevgi; Cicek, Neslihan; Agbas, Ayse; Nayir, Ahmet Nevzat; Konukoglu, Dildar; Kurugoglu, Sebuh; Sever, Lale; Canpolat, Nur; Caliskan, Salim; N/A; Akıncı, Nurver; Doctor; N/A; Koç University Hospital; N/AN/APublication Metadata only An 8-month-old infant with hypercalcemia and hyperphosphatemia-Answers(Springer, 2021) N/A; N/A; Özler, Oğuz; Yeşiltepe Mutlu, Rahime Gül; Taşdemir, Mehmet; Avcı, Şahin; Bilge, İlmay; Hatun, Şükrü; Undergraduate Student; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; 153511; 175867; N/A; 198907; 153504N/APublication Metadata only An 8-month-old infant with hypercalcemia and hyperphosphatemia: questions(Springer, 2021) N/A; N/A; Özler, Oğuz; Yeşiltepe Mutlu, Rahime Gül; Taşdemir, Mehmet; Avcı, Şahin; Bilge, İlmay; Hatun, Şükrü; Undergraduate Student; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; 153511; 175867; N/A; 198907; 153504N/A