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    Publication
    A multinational Delphi consensus to end the COVID-19 public health threat
    (Nature Research, 2022) Lazarus, Jeffrey V.; Romero, Diana; Kopka, Christopher J.; Karim, Salim Abdool; Abu-Raddad, Laith J.; Almeida, Gisele; Baptista-Leite, Ricardo; Barocas, Joshua A.; Barreto, Mauricio L.; Bar-Yam, Yaneer; Bassat, Quique; Batista, Carolina; Bazilian, Morgan; Chiou, Shu-Ti; del Rio, Carlos; Dore, Gregory J.; Gao, George F.; Gostin, Lawrence O.; Hellard, Margaret; Jimenez, Jose L.; Kang, Gagandeep; Lee, Nancy; Matičič, Mojca; McKee, Martin; Nsanzimana, Sabin; Oliu-Barton, Miquel; Pradelski, Bary; Pyzik, Oksana; Rabin, Kenneth; Raina, Sunil; Rashid, Sabina Faiz; Rathe, Magdalena; Saenz, Rocio; Singh, Sudhvir; Trock-Hempler, Malene; Villapol, Sonia; Yap, Peiling; Binagwaho, Agnes; Kamarulzaman, Adeeba; El-Mohandes, Ayman; Barreto, Mauricio; del Rio, Carlos; Abdulla, Salim; Addleman, Sarah; Aghayeva, Gulnara; Agius, Raymond; Ahmed, Mohammed; Ramy, Mohamed Ahmed; Aide, Pedro; Aleman, Soo; Alfred, Jean-Patrick; Ali, Shamim; Aliaga, Jorge; Aloudat, Tammam; Alqahtani, Saleh A.; Al-Salman, Jameela; Amuasi, John H.; Agrawal, Anurag; Anwar, Wagida; Araujo-Jorge, Tania; Artaza, Osvaldo; Asadi, Leyla; Awuku, Yaw; Baker, Michael; Barberia, Lorena; Bascolo, Ernesto; Belcher, Paul; Bell, Lizett; Benzaken, Adele; Bergholtz, Emil; Bhadelia, Nahid; Bhan, Anant; Bilodeau, Stephane; Bitrán, Ricardo; Bluyssen, Philomena; Bosman, Arnold; Bozza, Fernando A.; Brinkmann, Melanie M.; Brown, Andrew; Mellado, Bruce; Bukusi, Elizabeth; Bullen, Chris; Buonanno, Giorgio; Burgess, Rochelle; Butler, Matthew; Byakika-Kibwika, Pauline; Cabieses, Baltica; Carlsson, Gunilla; Cascini, Fidelia; Chabala, Chishala; Chakroun, Mohamed; Cheng K.K.; Chetty, Agnes; Chumachenko, Dmytro; Consalves, Gregg; Conway Morris, Andrew; Cordie, Ahmed; Corrah, Tumani; Crabtree-Ramírez, Brenda; Dashdorj, Naranjargal; Davidovitch, Nadav; de Souza, Luis Eugenio; Dhariwal, Akshay Chand; Druică, Elena; Erondu, Ngozi A.; Essar, Mohammad Yasir; Ewing, Andrew; Fanjul, Gonzalo; Feierstein, Daniel; Feigl-Ding, Eric; Figueroa, Ramon; Figueroa, John Peter; Fisher, Dale; Flores, Walter; Forero-Peña, David A.; Frumkin, Howard; Gamkrelidze, Amiran; Gandhi, Monica; Garcia, Patricia; Garcia-Basteiro, Alberto L.; García-Sastre, Adolfo; Garg, Suneela; Gbeasor-Komlanvi F.A.; Gershenson, Carlos; Gilada, Ishwar; Giovanella, Ligia; González, Marino; Green, Manfred S.; Greenhalgh, Trisha; Griffin, Paul; Griffin, Stephen; Grinsztejn, Beatriz; Anand, Tanu; Guerra, Germán; Guinto, Renzo; Gujski, Mariusz; Guner, Rahmet; Hamdy, Adam; Hâncean, Marian-Gabriel; Haniffa, Abusayeed; Hartigan-Go, Kenneth Y.; Hassan, Hoda K.; Hay, Simon I.; Heino, Matti T. J.; Hel, Zdenek; Hotez, Peter; Hu, Jia; Hukić, Mirsada; IJsselmuiden, Carel; Iroko, Davidson; Iskarous, Maged; Izugbara, Chimaraoke; Jacobs, Choolwe; Jadad, Alejandro R.; Jehan, Fyezah; Jordan, Ayana; Jroundi, Imane; Kain, Kevin; Kamberi, Fatjona; Karamov, Eduard; Karan, Abraar; Katz, Rebecca; Katzourakis, Aris; Kazembe, Abigail; Khamis, Faryal; Khamzayev, Komiljon; Khanyola, Judy; Khunti, Kamlesh; Kiguli-Malwadde, Elsie; Kim, Woo Joo; Kirenga, Bruce J.; Klimovský, Daniel; Kmush, Brittany L.; Knaul, Felicia; Kogevinas, Manolis; Kristensen, Frederik; Kumar, Dinesh; Kumar, Raman; Kvalsvig, Amanda; Lacerda, Marcus V.; Lal, Arush; Lawton, Tom; Lemery, Jay; Leonardi, Anthony J.; Li, Yuguo; Löttvall, Jan; Lounis, Mohamed; Maceira, Daniel; MacIntyre, C. Raina; Madani, Azzeddine; Magiorkinis, Gkikas; Malekzadeh, Reza; Choisy, Marc; Marcelin, Jasmine R.; Marks, Guy B.; Marr, Linsey; Marrazzo, Jeanne; Martina, Antonieta; Martín-Moreno, José M.; Mateos, Carlos; Mayxay, Mayfong; Mazarati, Jean Bapiste; Mboup, Souleymane; McDonald, Jennifer; McMillan, Faye; Mechili, Enkeleint; Medici, Andre; Davis, Sarah L. M.; Meier, Petra; Memish, Ziad A.; Menon, Jaideep; Menon, Purnima; Mesiano-Crookston, Jonathan; Michie, Susan; Mikolasevic, Ivana; Milicevic, Ognjen; Mishra, Asit Kumar; Mohamed, Rahma; Mokdad, Ali H.; Monroy-Valle, Michele; Morawska, Lidia; Moschos, Sterghios A.; Motawea, Karam; Mousavi, Sayed Hamid; Mumtaz, Ghina; Munene, Peter K.; Muñoz Almagro, Carmen; Muriuki, Janet; Muyingo, Sylvia; Naniche, Denise; Naylor, C. David; Ndembi, Nicaise; Nemec, Juraj; Nesteruk, Igor; Ngaruiya, Christine; Nguyen, Hung; Nikolova, Dafina; Nitzan, Dorit; Norheim, Ole; Noushad, Mohammed; Ntoumi, Francine; Nyborg, Gunhild Alvik; Ochodo, Eleanor; Odabasi, Zekaver; Okwen, Mbah Patrick; Olivia, Keiser; Ong, David S. Y., Opara, Ijeoma; Orozco, Miguel; Oshitani, Hitoshi; Pagel, Christina; Pai, Madhukar; Pálsdóttir, Björg; Papatheodoridis, Georgios Paraskevis, Dimitrios; Leigh, Jeanna Parsons; Pécoul, Bernard; Peichl, Andreas; Perez-Then, Eddy; Duc, Phuc Pham; Philippe, Cécile; Pineda Rojas, Andrea; Pladsen, Courtney; Pozniak, Anton; Quiroga, Rodrigo; Qureshi, Huma; Rampal, Sanjay; Ranney, Megan; Rathe, Laura; Ratzan, Scott; Raventos, Henriette; Rees, Helen; Reis, Renata; Ricciardi, Walter; Rizk, Nesrine; Robalo, Magda; Robertson, Eleanor; Robinson, Leanne; Rokx, Casper; Ros, Tamsin; Røttingen, John-Arne; Rubin, Meir; Ruxrungtam, Kiat; Sadirova, Shakhlo; Saha, Senjuti; Salgado, Nelly; Sanchez, Lizet; Sangaramoorthy, Thurka; Santamaria-Ulloa, Carolina; Santos, Renata; Sawaf, Bisher; Schneider, Matthias F.; Schooley, Robert T.; Sener, Alper; Sepulveda, Jaime; Shah, Jaffer; Shibani, Mosa; Shoib, Sheikh; Sikazwe, Izukanji; Šimaitis, Aistis; Gill, Amandeep Singh; Skhvitaridze, Natia; Sokolović, Milka; Solomon, Roma; Solórzano, Xavier; Springer, Sandra A.; Šrol, Jakub; Staines, Anthony; Stelfox, Henry T.; Strathdee, Steffanie; Sulaiman, Lokman Hakim; Sutton, Brett; Svanæs, Dag; Swed, Sarya; Sypsa, Vana; Sørensen, Kristine; Tajudeen, Raji; Tan, Amy; Tang, Julian; Tanner, Marcel; Sethi, Tavpritesh; Temmerman, Marleen; Than, Kyu Kyu; Tinto, Halidou; Tomètissi, Sênoudé Pacôme; Torres, Irene; Tshering K.P.; Tsiodras, Sotirios; Tsofa, Benjamin; Vahlne, Anders; Vargas, Juan Rafael; Bernal, Ivan Dario Velez; Ventura, Deisy; Vilasanjuan, Rafael; Vipond, Joe; Wamala-Andersson, Sarah; Wargocki, Pawel; West, Robert; Weyand, Angela; White, Trenton M.; Wolff, Guntram; Yao, Maosheng; Yates, Christian A.; Yeboah, Georgina; Yee-Sin, Leo; Yi, Siyan; Teo, Yik-Ying; Yong, Poovorawan; Zamora-Mesía, Victor; Øvrehus, Anne; Ergönül, Önder; Faculty Member; Koç Üniversitesi İş Bankası Enfeksiyon Hastalıkları Uygulama ve Araştırma Merkezi (EHAM) / Koç University İşbank Center for Infectious Diseases (KU-IS CID); School of Medicine; 110398
    Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19 pandemic1,2. Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel of 386 academic, health, non-governmental organization, government and other experts in COVID-19 response from 112 countries and territories to recommend specific actions to end this persistent global threat to public health. The panel developed a set of 41 consensus statements and 57 recommendations to governments, health systems, industry and other key stakeholders across six domains: communication; health systems; vaccination; prevention; treatment and care; and inequities. In the wake of nearly three years of fragmented global and national responses, it is instructive to note that three of the highest-ranked recommendations call for the adoption of whole-of-society and whole-of-government approaches1, while maintaining proven prevention measures using a vaccines-plus approach2 that employs a range of public health and financial support measures to complement vaccination. Other recommendations with at least 99% combined agreement advise governments and other stakeholders to improve communication, rebuild public trust and engage communities3 in the management of pandemic responses. The findings of the study, which have been further endorsed by 184 organizations globally, include points of unanimous agreement, as well as six recommendations with >5% disagreement, that provide health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.
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    Higher airborne pollen concentrations correlated with increased SARS-CoV-2 infection rates, as evidenced from 31 countries across the globe
    (National Academy of Sciences, 2021) Damialis, Athanasios; Gilles, Stefanie; Sofiev, Mikhail; Sofieva, Viktoria; Kolek, Franziska; Bayr, Daniela; Plaza, Maria P.; Leier-Wirtz, Vivien; Kaschuba, Sigrid; Ziska, Lewis H.; Bielory, Leonard; Makra, László; del Mar Trigo, Maria; Traidl-Hoffmann, Claudia; Oliver, Gilles; Pham-Thi, Nhân; Thibaudon, Michel; Arino, Arturo H.; Belmonte, Jordina; Cervigon Morales, Patricia; De Linares, Concepción; Fernández, Delia; Fernández-Rodriguez, Santiago; Gabaldón Arguisuelas, Antonia; Galán, Carmen; González-Alonso, Mónica; Lara, Beatriz; Moreno Grau, José María; Oteros, José; Pérez-Badia, Rosa; Pérez-De-Zabalza, Anabel; Picornell, Antonio; Recio, Marta; Robles, Estrella; Rodríguez-Fernández, Alberto; Rodríguez-Rajo, F. Javier; Rojo, Jesús; Ruiz Valenzuela, Luis; Bergmann, Karl-Christian; Werchan, Barbora; Werchan, Matthias; Buters, Jeroen T.M.; Bastl, Maximilian; Dunker, Susanne; Hornick, Thomas; González Roldán, Nestor; Gilge, Stefan; Clot, Bernard; Finemann, Stanley; Ford, Linda; Gomez, Robert Anthony; Kamboj, Sanjay; Wilhelm, Wayne; Beggs, Paul J.; Burton, Pamela; Davies, Janet M.; Haberle, Simon Graeme; Katelaris, Constance Helen; Keaney, Ben; Milic, Andelija; Miller, Victoria; van Haeften, Shanice; Bonini, Maira; Bordin, Anna; Ceriotti, Valentina; Cristofolini, Fabiana; Cristofori, Antonella; Gottardini, Elena; Marcer, Guido; Marraccini, Paolo; Mascagni, Paolo; Meriggi, Antonio; Pace, Loretta; Pini, Alberto; Tacca, Maria Cristina; Bruffaerts, Nicolas; Hoebeke, Lucie; Adams-Groom, Beverley; Pashley, Catherine H.; Satchwell, Jack; Skjøth, Carsten; Symon, Fiona A.; Antunes, Celia M.; Caeiro, Elsa; Camacho, Irene Gomes Câmara; Costa, Ana R.; Deus, Ricardo João Ratola Capela; Ferreira, Manuel Branco; Fonseca, Joao Almeida Lopes; Galveias, Ana; Ribeiro, Helena; Tavares, Beatriz; Grewling, Łukasz; Grinn-Gofroń, Agnieszka; Jurkiewicz, Dariusz; Kalinowska, Ewa; Lipiec, Agnieszka; Myszkowska, Dorota; Piotrowska-Weryszko, Krystyna; Puc, Malgorzata; Rapiejko, Anna; Rapiejko, Piotr; Weryszko-Chmielewska, Elzbieta; Ziemianin, Monika; Berman, Dilys; Hoek, Werner; Manjra, Ahmed Ismail; Peter, Jonathan; Dahl, Åslög; Ekebom, Agneta; Stjepanovic, Barbara; Večenaj, Ana; Çelenk, Sevcan; Göksel, Özlem; Göksel, Tuncay; Güvensen, Aykut A.; Munevver, Nur; Acar Şahin, Aydar; Uğuz, Ulaş U.; Kajtor-Apatini, Dóra; Magyar, Donat; Szigeti, Tamas; Sikoparija, Branko; Kofol Seliger, Andreja; Simčič, Anja; Oh, Jae; Charalampopoulos, Athanasios; Vokou, Despoina; Rasmussen, Karen; Barrionuevo, Laura Beatriz; Ramon, German Dario; de Weger, Letty A.; Koenders, Mieke M.J.F.; van Vliet, Arnold J.H.; Dušička, Jozef; Lafférsová, Janka; Šèevkováč, Jana; Rybníček, Ondøej; Coates, Frances; Jurgens, Dawn; Šauliene, Ingrida; Severova, Elena; Rodinkova, Victoria; Bortnyk, Mykyta; Palamarchuk, Olena; Yasniuk, Maryna; Louna-Korteniemi, Maria; Pätsi, Sanna; Saarto, Annika; Toiviainen, Linnea; Sozinova, Olga; Jia, Peng; N/A; N/A; Yazıcı, Duygu; Saçkesen, Cansın; PhD Student; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); Graduate School of Health Sciences; School of Medicine; N/A; 182537
    Pollen exposure weakens the immunity against certain seasonal respiratory viruses by diminishing the antiviral interferon response. Here we investigate whether the same applies to the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is sensitive to antiviral interferons, if infection waves coincide with high airborne pollen concentrations. Our original hypothesis was that more airborne pollen would lead to increases in infection rates. To examine this, we performed a cross-sectional and longitudinal data analysis on SARS-CoV-2 infection, airborne pollen, and meteorological factors. Our dataset is the most comprehensive, largest possible worldwide from 130 stations, across 31 countries and five continents. To explicitly investigate the effects of social contact, we additionally considered population density of each study area, as well as lockdown effects, in all possible combinations: without any lockdown, with mixed lockdown−no lockdown regime, and under complete lockdown. We found that airborne pollen, sometimes in synergy with humidity and temperature, explained, on average, 44% of the infection rate variability. Infection rates increased after higher pollen concentrations most frequently during the four previous days. Without lockdown, an increase of pollen abundance by 100 pollen/m3 resulted in a 4% average increase of infection rates. Lockdown halved infection rates under similar pollen concentrations. As there can be no preventive measures against airborne pollen exposure, we suggest wide dissemination of pollen−virus coexposure dire effect information to encourage high-risk individuals to wear particle filter masks during high springtime pollen concentrations.
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    Improved 3D with super stereoscopy technique
    (Blackwell Publishing, 2014) N/A; N/A; Department of Electrical and Electronics Engineering; Akşit, Kaan; Niaki, Amir Hossein Ghanbari; Ürey, Hakan; PhD Student; Master Student; Faculty Member; Department of Electrical and Electronics Engineering; Graduate School of Sciences and Engineering; Graduate School of Sciences and Engineering; College of Engineering; N/A; N/A; 8579
    This paper introduces a new major milestone on stereoscopic displays, where users no longer suffer from the accommodation-vergence conflict problem with a perfected monocular parallax. Our method provides multiple views to a single eye by using special apertures equipped with filters in front of the user's eyes in which the design is embedded into conventional stereoscopic glasses or special stereoscopic contact lenses. Thus, visual fatigue originated from accommodation-vergence conflict is avoided. Through informal subjective tests, we have shown that the depth perception, accommodation, and vergence of the eyes can be enhanced. The technique is also capable of converting multi-view displays to Super Multi-View (SMV) displays.
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    Investigate the utilization of novel natural photosensitizers for the performance of dye-sensitized solar cells (DSSCs)
    (Elsevier B.V., 2024) Patunrengi, Iswadi I.; Arofiati Noor, Fatimah; Nasyori, Achmad; Graduate School of Sciences and Engineering
    Dye-sensitized solar cells (DSSCs) offer a promising route for sustainable energy conversion, with natural photosensitizers emerging as attractive alternatives to conventional synthetic dyes due to their abundant resources, cost-effectiveness, and eco-friendly materials. However, the efficiency of DSSC utilizing natural photosensitizer remains low. In this study, we investigate the utilization of novel natural photosensitizers extracted from gambier leaves, gambier branches, cinnamon, and petiole of tectona leaves, which contain flavonoids/tannins, chlorophyll, and anthocyanins, aiming to achieve high-performance DSSCs. Five different solvents—ethanol, isopropanol, distilled water, methanol, and Zamzam water—are explored to optimize the extraction process of the natural dyes. The doctor blade technique is employed to coat TiO2 nanomaterials onto ITO glass substrates. UV–Vis spectrophotometry and FTIR spectroscopy are used to characterize the optical properties and structural composition of the dyes, revealing that flavonoid/tannin groups are the primary compounds responsible for light harvesting. The DSSC performance is evaluated under a 30 W lamp, adjusted to light intensity of 10 mW/cm2. As a result, the DSSCs using gambier leaf extract as photosensitizer demonstrate the highest recorded efficiency of 4.71 %, with a Jsc of 2.95 mAcm−2 and a Voc of 0.64 V. These findings contribute to advancing DSSC technology by leveraging the potential of natural photosensitizers for sustainable energy conversion applications. © 2024
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    Investigating mechanical deformation’s role in cochlear implant durability
    (Public Library of Science, 2024) Blank, Tatiana; Ahrens, André Marcel; Klose, Christian; Lenarz, Thomas; Maier, Hans Jürgen; Department of Mechanical Engineering; Canadinç, Demircan; Department of Mechanical Engineering; College of Engineering
    Platinum and platinum-based alloys are used as the electrode material in cochlear implants because of the biocompatibility and the favorable electrochemical properties. Still, these implants can fail over time. The present study was conducted to shed light on the effects of microstructure on the electrochemical degradation of platinum. After three days of stimulation with a square wave signal, corrosive attack appeared on the platinum surface. The influence of mechanical deformation, in particular rolling, on the corrosion resistance of platinum was also prominent. The cyclic voltammetry showed a clear dependence on the electrolyte used, which was interpreted as an influence of the buffer in the artificial perilymph used. In addition, the polarization curves showed a shift with grain size that was not expected. This could be attributed to the defects present on the surface. These findings are crucial for the manufacture of cochlear implants to ensure their long-term functionality. Copyright: © 2024 Blank et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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    Modular multi-projection multi-view autostereoscopic display using MEMS laser projectors
    (Blackwell Publishing, 2014) N/A; Department of Electrical and Electronics Engineering; Department of Electrical and Electronics Engineering; Akşit, Kaan; Ölçer, Selim; Ürey, Hakan; PhD Student; Other; Faculty Member; Department of Electrical and Electronics Engineering; Graduate School of Sciences and Engineering; College of Engineering; College of Engineering; N/A; N/A; 8579
    A new modular multi-projection multi-user multiview autostereoscopic display structure based on microelectromechanical systems (MEMS) laser projectors is presented. The system contains an array of MEMS laser projectors, a vertical diffuser, and the driving electronics. Each projector provides a slit of the whole image observed through the vertical diffuser. The structure does not require super position of the content among the projectors. Unlike similar type of displays, the size of the projection display hardware decreased dramatically. The structure has the capability to provide horizontal expansion in the screen size, and in number of different perspectives shown. Mentioned capabilities can be enhanced by using more projectors, by increasing the distance between projectors and the screen, and by changing the diffusion angle of the vertical diffuser in the minor axis. The inhouse built prototype with 18 projectors displays an image with a resolution of 234times848, and 36 different perspectives. The size of the image at the screen is 16 cm x 72 cm.
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    Paper no 15.1: augmented reality and 3D displays using pico-projectors
    (Blackwell Publishing, 2013) N/A; N/A; N/A; Department of Electrical and Electronics Engineering; Akşit, Kaan; Eldeş, Osman; Hedili, M. Kıvanç; Ürey, Hakan; PhD Student; Master Student; Master Student; Faculty Member; Department of Electrical and Electronics Engineering; Graduate School of Sciences and Engineering; Graduate School of Sciences and Engineering; Graduate School of Sciences and Engineering; College of Engineering; N/A; N/A; N/A; 8579
    Pico-projectors based on ME MS scanners and RGB lasers provide a powerful platform for not only mobile projectors but also for various 3D display architectures and augmented reality. First part of the paper discusses two recently developed 3D display techniques: a stereoscopic display using only one pico-projector passive polarized glasses and an autostereoscopic multiuser multiview display using an array of pico-projectors. Second part of the paper discusses various augmented reality applications enabled by a pico-projector and a special micro-optical screen. Those technologies can be expected to play an important role in the future of human-computer interface.