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Publication Metadata only COVID-19: risk factors increasing disease and scoring(DOC Design and Informatics Co. Ltd., 2021) Demirtürk, Neşe; Tekin, Süda; Faculty Member; School of Medicine; 42146Coronavirus disease 2019 (COVID-19), is caused by a novel coronavirus named as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It became a major global health threat in a short time after being declared by the World Health Organization (WHO) as a pandemic on March 11, 2020. Viral, environmental, and host factors play a role in the course of COVID-19. The disease is more common in the elderly, men, and people with diabetes mellitus, hypertension, cardiovascular disease, chronic renal disease, and malignancy. While some risk scores are used to predict ICU admission and mortality, they are not specific to COVID-19. Identifying high-risk individuals and prevent-ing their infection can reduce mortality in the disease. / Şiddetli akut solunum sendromu virusu (SARS-CoV-2)’nun neden olduğu koronavirus hastalığı 2019 (COVID-19), 11 Mart 2020’de Dünya Sağlık Örgütü tarafından pandemi ilan edildikten sonra, kısa sürede büyük bir küresel sağlık tehdidi haline geldi. COVID-19’un gelişiminde viral, çevresel ve konak faktörleri rol oynamaktadır. Hastalık; yaşlılar ve erkeklerin yanı sıra diabetes mellitus, hipertansiyon, kardiyovasküler hastalık, kronik böbrek hastalığı ve malignitesi olan kişilerde daha yaygındır. Yoğun bakıma yatışı ve mortaliteyi tahmin etmek için kullanılan bazı risk skorları olmakla birlikte COVID-19’a özgül değildirler. Yüksek riskli bireylerin belirlenmesi ve infeksiyonlarının önlenmesi hastalıkta mortaliteyi azaltabilir.Publication Metadata only Mortality analysis of COVID-19 infection in chronic kidney disease, haemodialysis and renal transplant patients compared with patients without kidney disease: A nationwide analysis from Turkey(Oxford University Press, 2021) Ozturk S.; Turgutalp K.; Arici M.; Odabas A.R.; Altiparmak M.R.; Aydin Z.; Cebeci E.; Basturk T.; Soypacaci Z.; Sahin G.; Ozler T.E.; Kara E.; Dheir H.; Eren N.; Suleymanlar G.; Islam M.; Ogutmen M.B.; Sengul E.; Ayar Y.; Dolarslan M.E.; Bakirdogen S.; Safak S.; Gungor O.; Sahin I.; Mentese I.B.; Merhametsiz O.; Oguz E.G.; Genek D.G.; Alpay N.; Aktas N.; Duranay M.; Alagoz S.; Colak H.; Adibelli Z.; Pembegul I.; Hur E.; Azak A.; Taymez D.G.; Tatar E.; Kazancioglu R.; Oruc A.; Yuksel E.; Onan E.; Turkmen K.; Hasbal N.B.; Gurel A.; Sahutoglu T.; Gok M.; Seyahi N.; Sevinc M.; Ozkurt S.; Sipahi S.; Bek S.G.; Bora F.; Demirelli B.; Oto O.A.; Altunoren O.; Tuglular S.Z.; Demir M.E.; Ayli M.D.; Huddam B.; Tanrisev M.; Bozaci I.; Gursu M.; Bakar B.; Tokgoz B.; Tonbul H.Z.; Yildiz A.; Sezer S.; Ates K.; N/A; Yelken, Berna; Doctor; N/A; Koç University Hospital; N/ABackground: Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand as one of the established potential risk factors for severe coronavirus disease 2019 (COVID-19). Case morbidity and mortality rates for any type of infection have always been much higher in CKD, haemodialysis (HD) and RT patients than in the general population. A large study comparing COVID-19 outcome in moderate to advanced CKD (Stages 3-5), HD and RT patients with a control group of patients is still lacking. Methods: We conducted a multicentre, retrospective, observational study, involving hospitalized adult patients with COVID-19 from 47 centres in Turkey. Patients with CKD Stages 3-5, chronic HD and RT were compared with patients who had COVID-19 but no kidney disease. Demographics, comorbidities, medications, laboratory tests, COVID-19 treatments and outcome [in-hospital mortality and combined in-hospital outcome mortality or admission to the intensive care unit (ICU)] were compared. Results: A total of 1210 patients were included [median age, 61 (quartile 1-quartile 3 48-71) years, female 551 (45.5%)] composed of four groups: Control (n = 450), HD (n = 390), RT (n = 81) and CKD (n = 289). The ICU admission rate was 266/ 1210 (22.0%). A total of 172/1210 (14.2%) patients died. The ICU admission and in-hospital mortality rates in the CKD group [114/289 (39.4%); 95% confidence interval (CI) 33.9-45.2; and 82/289 (28.4%); 95% CI 23.9-34.5)] were significantly higher than the other groups: HD = 99/390 (25.4%; 95% CI 21.3-29.9; P<0.001) and 63/390 (16.2%; 95% CI 13.0-20.4; P<0.001); RT = 17/81 (21.0%; 95% CI 13.2-30.8; P = 0.002) and 9/81 (11.1%; 95% CI 5.7-19.5; P = 0.001); and control = 36/450 (8.0%; 95% CI 5.8-10.8; P<0.001) and 18/450 (4%; 95% CI 2.5-6.2; P<0.001). Adjusted mortality and adjusted combined outcomes in CKD group and HD groups were significantly higher than the control group [hazard ratio (HR) (95% CI) CKD: 2.88 (1.52- 5.44); P = 0.001; 2.44 (1.35-4.40); P = 0.003; HD: 2.32 (1.21- 4.46); P = 0.011; 2.25 (1.23-4.12); P = 0.008), respectively], but these were not significantly different in the RT from in the control group [HR (95% CI) 1.89 (0.76-4.72); P = 0.169; 1.87 (0.81-4.28); P = 0.138, respectively]. Conclusions: Hospitalized COVID-19 patients with CKDs, including Stages 3-5 CKD, HD and RT, have significantly higher mortality than patients without kidney disease. Stages 3-5 CKD patients have an in-hospital mortality rate as much as HD patients, which may be in part because of similar age and comorbidity burden. We were unable to assess if RT patients were or were not at increased risk for in-hospital mortality because of the relatively small sample size of the RT patients in this study.Publication Metadata only Trauma-informed care for perinatal women during the COVID-19 pandemic: a survey of nurses and midwives in Turkey(Churchill Livingstone, 2023) Polivka Barbara; Christian Becky; Yeşilçınar İlknur; N/A; Salameh, Taghreed Nayel Mohammad; Faculty Member; School of Nursing; 329120Objectives: There is a paucity of evidence on the provision of trauma-informed care among nurses and midwives during the pandemic.Therefore, this online survey of Turkish nurses and midwives aimed to: describe reported maternal concerns and anxieties during the COVID-19 pandemic; and explore aspects of trauma-informed care for perinatal women during the COVID-19 pandemic (i.e., nurses’ and midwives’ knowledge, opinions, perceived competence, current practices, and implementation barriers). Design: A cross-sectional descriptive survey design. Setting and participants: A web-based survey conducted between June 2021 to December 2021. A total of 102 nurses and midwives comprised the final sample of this study. Findings: The safety of COVID-19 vaccine was both the most common maternal concern (73%) and the most frequently noted maternal source of anxiety (79%) reported to nurses and midwives by perinatal women. Most nurses and midwives were knowledgeable of, held favorable opinion about, and perceived moderate competence in trauma-informed care. The most frequently provided practice was encouraging mothers to make use of their own social support system (82%). Time constrains and lack of resources were perceived as somewhat to significant barriers to providing trauma-informed care during the pandemic. Conclusions: Access to correct information related to COVID-19 vaccination is necessary to reduce maternal anxiety. Since perinatal nurses and midwives had favorable opinions concerning implementing trauma-informed care, successful strategies for mitigating the implementation barriers are essential to facilitate the provision of trauma-informed care during the pandemic.