Researcher: Öğe, Ali Emre
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Öğe, Ali Emre
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Publication Metadata only Differentiation of post-polio syndrome from prior poliomyelitis sequela by assessing paraspinal muscle involvement in magnetic resonance imaging(MDPI, 2024) Terlemez, Rana; Cetin, Burak Ugur; Topaloğlu, Mahir; Sarıkaya, Deniz; Peker, Ahmet; Şentürk, Yunus Emre; Öğe, Ali Emre; Ketenci, Ayşegül; School of Medicine; Koç University HospitalBackground/Objectives: Post-polio syndrome (PPS) affects former polio patients, manifesting decades after initial infection with progressive symptoms like pain, fatigue, and muscle weakness. Diagnosis relies on the clinical criteria and exclusion of other probable causes. The purpose of this study is to determine the scope and new diagnostic value of magnetic resonance imaging (MRI) in identifying muscle involvement in PPS and distinguishing it from prior poliomyelitis (PPM). Methods: This study was approved by the Koç University Ethics Committee with Approval No. 2023.409.IRB2.090. Electronic medical archives from two academic institutions were searched for records tagged with ICD code B-91 for poliomyelitis sequalae. The resulting search query of 291 records was manually sorted for PPS and PPM, medical history, clinical examination findings, and lumbar MR images down to 32 patients. Two independent radiologists evaluated the paraspinal musculature in the MRIs using the Mercuri scale. Inter-rater agreement, comparison of the paraspinal musculatures between groups, and their relationship to leg involvement were assessed with the resulting data. Results: Inter-rater agreement was found to be almost perfect across all muscles, except for the multifidus muscle. When clinical examination findings were included for these muscles, quadratus lumborum (QL) degradation was found in both right-side (p = 0.017) and left-side (p = 0.002) leg involvement. Conclusions: QL muscle deterioration may serve as a diagnostic marker for PPS, potentially guiding lumbar pain treatment through rehabilitation. © 2024 by the authors.Publication Metadata only Effect of sagittal split osteotomy with medpor (r) porous polyethylene implant on masticatory reflex(Annals Dental Specialty, 2022) Genc, Aysenur; Isler, Sabri Cemil; Matur, Zeliha; N/A; Öğe, Ali Emre; Doctor; N/A; Koç University Hospital; N/AThe purpose of this report was to provide data regarding whether the use of alloplastic implants to the mandibular body and angle as an occasional adjunct to orthognathic surgery affects the jaw reflex. Two patients to whom sagittal split osteotomy with Medpor porous polyethylene implant was performed due to severe mandibular asymmetry were included. To elucidate alterations in reflexes, serial surface electromyographic data were collected from the masseter muscle. The latencies and durations of the silent period were measured. In both patients, massetery inhibitory reflex response on the Medpor-augmented side was not elicited at the postoperative first month. Although postoperative masticatory inhibitory reflex latencies, durations, and configurations were similar between the right and left sides in both patients, we did not elicit the first silent period response following porous polyethylene implant placement at the postoperative sixth month. In conclusion, porous polyethylene implants may decrease masticatory reflex activity. The clinical use of implants made of porous polyethylene seems to be safe; however, indications, chances, and risks should be carefully evaluated prior to application.