Researcher: Ali, Mohsin
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Ali, Mohsin
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Publication Open Access An integrated and flexible ultrasonic device for continuous bladder volume monitoring(Nature Research, 2024) Akcoren, Dincay; Eminoglu, Burak; Department of Mechanical Engineering; Department of Mechanical Engineering; Toymus, Alp Timuçin; Yener, Umut Can; Bardakçı, Emine; Temel, Özgür Deniz; Köseoğlu, Ersin; Ali, Mohsin; Kılıç, Rasim; Beker, Levent; Tarcan, Tufan; ; Graduate School of Sciences and Engineering; School of Medicine; College of Engineering;Bladder volume measurement is critical for early detection and management of lower urinary tract dysfunctions. Current gold standard is invasive, and alternative technologies either require trained personnel or do not offer medical grade information. Here, we report an integrated wearable ultrasonic bladder volume monitoring device for accurate and autonomous continuous monitoring of the bladder volume. The device incorporates flexible and air-backed ultrasonic transducers and miniaturized control electronics with wireless data transmission capability. We demonstrate the real-life application of the device on healthy volunteers with various bladder shapes and sizes with high accuracy. Apart from the lower urinary tract dysfunctions, the proposed technology could also be adapted for various wearable ultrasonic applications. © The Author(s) 2024.Publication Metadata only Near-infrared triggered degradation for transient electronics(American Chemical Society, 2024) İstif, Emin; Department of Physics;Department of Mechanical Engineering; Ali, Mohsin; Özüaçıksöz, Elif Yaren; Morova, Yağız; Beker, Levent; Koç University Surface Science and Technology Center (KUYTAM) / Koç Üniversitesi Yüzey Teknolojileri Araştırmaları Merkezi (KUYTAM); Graduate School of Sciences and Engineering; College of Sciences; College of EngineeringElectronics that disintegrate after stable operation present exciting opportunities for niche medical implant and consumer electronics applications. The disintegration of these devices can be initiated due to their medium conditions or triggered by external stimuli, which enables on-demand transition. An external stimulation method that can penetrate deep inside the body could revolutionize the use of transient electronics as implantable medical devices (IMDs), eliminating the need for secondary surgery to remove the IMDs. We report near-infrared (NIR) light-triggered transition of metastable cyclic poly-(phthalaldehyde) (cPPA) polymers. The transition of the encapsulation layer is achieved through the conversion of NIR light to heat, facilitated by bioresorbable metals, such as molybdenum (Mo). We reported a rapid degradation of cPPA encapsulation layer about 1 min, and the rate of degradation can be controlled by laser power and exposure time. This study offers a new approach for light triggerable transient electronics for IMDs due to the deep penetration depth of NIR light through to organs and tissues.