Researcher: Muradoğlu, Serra Küpçüoğlu
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Muradoğlu, Serra Küpçüoğlu
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Publication Metadata only I'm not alone-my take-away message from the my friend diabetes camp(Springernature, 2020) N/A; N/A; Yeşiltepe Mutlu, Rahime Gül; Gökçe, Tuğba; Can, Ecem; Muradoğlu, Serra Küpçüoğlu; Hatun, Şükrü; Faculty Member; Doctor; Nurse; Doctor; Faculty Member; School of Medicine; N/A; N/A; N/A; School of Medicine; N/A; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; 153511; N/A; N/A; N/A; 153504N/APublication Metadata only A short-term evaluation of children with diabetes using medtronic 780g system- a single center experience from Turkey(Mary Ann Liebert, Inc, 2022) N/A; N/A; Yeşiltepe Mutlu, Rahime Gül; Eviz, Elif; Can, Ecem; Gökçe, Tuğba; Muradoğlu, Serra Küpçüoğlu; Hatun, Şükrü; Faculty Member; Researcher; Nurse; Doctor; Doctor; Faculty Member; School of Medicine; School of Medicine; N/A; N/A; N/A; School of Medicine; N/A; N/A; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; 153511; 327618; N/A; N/A; N/A; 153504N/APublication Metadata only The my friend diabetes carbohydrate bolus calculator: user experiences(Mary Ann Liebert, Inc, 2022) N/A; N/A; Karakuş, Kağan Ege; Gökçe, Tuğba; Can, Ecem; Muradoğlu, Serra Küpçüoğlu; Eviz, Elif; Yeşiltepe Mutlu, Rahime Gül; Hatun, Şükrü; Undergraduate Student; Doctor; Nurse; Doctor; N/A; Researcher; Faculty Member; Faculty Member; School of Medicine; N/A; N/A; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; 327618; 153511; 153504N/APublication Metadata only Impact of milk as a bedtime snack on nocturnal glycemia in preschool children with Type 1 diabetes: case series(Türk Diyetisyenler Derneği, 2020) Gökçe, Tuğba; Yeşiltepe Mutlu, Rahime Gül; Can, Ecem; Eviz, Elif; Muradoğlu, Serra Küpçüoğlu; Hatun, Şükrü; Doctor; Faculty Member; Nurse; Faculty Member; Doctor; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; N/A; School of Medicine; Koç University Hospital; N/A; 153511; N/A; 327618; N/A; 153504Young children with type 1 diabetes (T1D) present special challenges for intensive diabetes management and glycemic variability. Young children face many difficulties in diabetes management, such as having more frequent hypoglycemia and hyperglycemia, lack of awareness of hypoglycemia, less residual beta cell function, severe hypoglycemia and long-term neurocognitive effects due to chronic hyperglycemia. Many parents routinely give bedtime snacks, regardless of glucose value, because of the fear of nocturnal hypoglycemia. Having a habit of drinking milk before sleeping at night is an attitude peculiar to our country. In our clinic, it was observed by examining Continuous Glucose Monitoring (CGM) data that drinking milk at night snacks caused hyperglycemia during the night in young children who were followed-up in our clinic. In case of not drinking milk, it was observed that the course of glucose at night was in the target range (70-180 mg/dL). In this article, the effects of medical and medical nutrition therapy and milk consumption as bedtime snack on CGM data of two patients aged 3-5 years with follow-up in our department is presented. / Öz: Tip 1 diyabet (T1D) tanılı küçük çocuklar diyabet yönetimi ve glisemik değişkenlik bakımından ayrı bir yere sahiptir. Küçük çocuklar (<7 yaş), hipoglisemi ve hipergliseminin daha sık görülmesi, hipoglisemi bulgularını ifade edememeleri, rezidüel beta hücre fonksiyonunun az olması, ciddi hipoglisemi atakları ve kronik hiperglisemiye bağlı uzun dönemde nörokognitif etkilenmenin daha fazla olması gibi birçok zorlukla karşı karşıyadır. Bu zorluklar ebeveynlere endişe olarak yansımakta ve birçok ebeveyn gece hipoglisemisi korkusu nedeniyle glukoz değeri ne olursa olsun rutin bir şekilde çocuğa gece ara öğünü vermektedir. Ülkemizde çocukların gece uyumadan önce ve sabah süt içme alışkanlıkları olması sebebiyle süt sık tüketilen bir seçenek olmaktadır. Kliniğimizde izlenen küçük yaş grubu çocukların Sürekli Glukoz İzlem (SGİ) verilerinde süt içirip uyutmanın gece boyunca hiperglisemiye neden olduğu, süt vermenin bırakılması durumunda ise gece glukoz seyrinin hedef aralıkta (70-180 mg/dL) kalma oranının arttığı gözlenmiştir. Bu yazıda kliniğimizde izlenen 3-5 yaş arasındaki iki olgunun tıbbi beslenme tedavisi ve gece ara öğününde verilen sütün SGİ verilerine yansıması paylaşılacaktır.Publication Metadata only How do bedtime snack and no snack options affect overnight glycemia in young children with diabetes: preliminary cgm results(Mary Ann Liebert, Inc, 2022) Ozel, H. Gokmen; N/A; Gökçe, Tuğba; Hatun, Şükrü; Karakuş, Kağan Ege; Yeşiltepe Mutlu, Rahime Gül; Muradoğlu, Serra Küpçüoğlu; Eviz, Elif; Can, Ecem; Doctor; Faculty Member; Undergraduate Student; Faculty Member; Doctor; Researcher; Other; Koç University Hospital; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; School of Medicine; Koç University Hospital; N/A; 153504; N/A; 153511; N/A; 327618N/APublication Metadata only An evaluation of the knowledge and attitudes of school staff related to diabetes care at school: the 10th year of the "diabetes program at school" in Turkey(Wiley, 2021) Cemhan, Kardelen; Kurtulmus, Mehmet Fatih; Gulsen, Murat; Aycan, Zehra; Darendeliler, Feyza; Ulger, Ozlem; Bulanik, Melek; Yardim, Nazan; N/A; Gökçe, Tuğba; Muradoğlu, Serra Küpçüoğlu; Can, Ecem; Sakarya, Sibel; Yeşiltepe Mutlu, Rahime Gül; Hatun, Şükrü; Doctor; Doctor; Nurse; Faculty Member; Faculty Member; Faculty Member; N/A; N/A; N/A; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; 172028; 153511; 153504The aim of this study was to measure the knowledge and attitudes of school staff regarding care in school for children with type 1 diabetes and to evaluate the contribution of the "Diabetes Program at School"(DPS). The data were collected through an online survey consisting of 55 questions, which included 39 knowledge and 16 attitude questions. The survey was delivered to the participating school staff via a link. A total of 55,677 people who completed 100% of the survey were included. of the participants, 76% were teachers, 23% were school administrators and 0.1% were school nurses. 73% (40732) of the participants stated that they had heard about the "DPS". of the participants who were aware of the DPS 75%, 50%, and 41% stated an increase in their knowledge level, self-confidence, and awareness respectively. Both scores were positively associated with being female and school nurse, having students with diabetes in the school, having been trained in childhood diabetes, being familiar with the program and being from the Western region of Turkey. The DPS is well known among school staff including teachers, school administrators, and school nurses. However, there are clear regional differences in the knowledge and attitude of school staff regarding diabetes care at school. Therefore, regional differences should be taken into account when planning the necessary interventions to prevent any further increase in the current inequalities. In addition, increasing the number of school nurses, together with strengthening the knowledge and attitude of school staff, can improve the level of diabetes care at school.Publication Metadata only Insulin requirements for basal and auto-correction insulin delivery in advanced hybrid closed-loop system: 4193 days’ real-world data of children in two different age groups(SAGE Publications Inc., 2022) N/A; N/A; Karakuş, Kağan Ege; Yeşiltepe Mutlu, Rahime Gül; Gökçe, Tuğba; Eviz, Elif; Can, Ecem; Muradoğlu, Serra Küpçüoğlu; Hatun, Şükrü; Undergraduate Student; Faculty Member; Doctor; Researcher; Nurse; Doctor; Faculty Member; School of Medicine; School of Medicine; N/A; School of Medicine; N/A; N/A; School of Medicine; N/A; N/A; Koç University Hospital; N/A; Koç University Hospital; Koç University Hospital; N/A; N/A; 153511; N/A; 327618; N/A; N/A; 153504Background: The insulin requirements of people with type 1 diabetes (T1D) can vary throughout the day due to factors such as biorhythm, exercise, and food intake. The MiniMed 780G system delivers micro boluses to adjust basal insulin and delivers auto-correction boluses to meet insulin needs when micro bolus increases are insufficient. Through analysis of MiniMed 780G data, this study investigates the variations in insulin requirements throughout the day. Methods: 4193 days’ pump and continuous glucose monitoring (CGM) data of 34 children using MiniMed 780G were collected from Medtronic CareLink. Micro and auto-correction boluses were analyzed on an hourly basis for two age groups: below nine years old and above nine years old. Glycemic metrics were analyzed based on International CGM consensus. Results: The mean age was 12.3 years and mean duration of diabetes was 6.1 years. The mean time in range (TIR) and glucose management indicator (GMI) were 80.5% and 6.6%, respectively. The micro bolus (basal) ratio between 05.00 and 07.00 was significantly higher than the ratio between 10.00 and 03.00 (P <.01), whereas micro bolus was significantly lower between 19.00 and 21.00 than those between 00.00 and 10.00 (P <.001). The auto-correction ratio between 21.00 and 00.00 was significantly higher than those between 03.00-17.00 (P <.001) and 19.00-21.00 (P =.008), whereas auto-correction was significantly lower between 07.00 and 10.00 than those between 10.00 and 03.00 (P <.001). The micro bolus ratio was significantly higher in children below nine years old than in children above nine years old between 21.00-00.00 (P =.026) and 00.00-03.00 (P =.003). Conclusion: The basal insulin need follows a diurnal pattern with two significantly different periods—high between 00.00 and 10.00 and low between 10.00 and 00.00. The auto-correction rates are low between 05.00 and 10.00 and show an increasing pattern peaking between 21.00 and 00.00. These findings are compatible with the dawn and reverse dawn phenomena.Publication Metadata only An evaluation of MiniMed™ 780G system performance in childhood: a single center experience from Turkey(Karger, 2022) N/A; N/A; N/A; N/A; N/A; N/A; Eviz, Elif; Yeşiltepe Mutlu, Rahime Gül; Can, Ecem; Gökçe, Tuğba; Muradoğlu, Serra Küpçüoğlu; Hatun, Şükrü; Researcher; Faculty Member; Nurse; Doctor; Doctor; Faculty Member; School of Medicine; School of Medicine; N/A; N/A; N/A; School of Medicine; Koç University Hospital; 327618; 153511; N/A; N/A; N/A; 153504N/APublication Metadata only Insulin requirements for basal and auto-correction insulin delivery in minimed 780g: a real-world data of children in 2 different age groups(Mary Ann Liebert, Inc, 2022) N/A; N/A; Karakuş, Kağan Ege; Yeşiltepe Mutlu, Rahime Gül; Eviz, Elif; Can, Ecem; Gökçe, Tuğba; Muradoğlu, Serra Küpçüoğlu; Hatun, Şükrü; Undergraduate Student; Faculty Member; Researcher; Nurse; Doctor; Doctor; Faculty Member; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; School of Medicine; N/A; N/A; N/A; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; 153511; 327618; N/A; N/A; N/A; 153504N/APublication Metadata only The Simplest way of assessing memory and attention function in daily clinical practice(Future Medicine, 2016) Arikan, Mehmet Kemal; Tarhan, Nevzat; Uysal, Omer; Gunay, Barlas; Küçük, Zeynep; N/A; Muradoğlu, Serra Küpçüoğlu; Doctor; N/A; Koç University Hospital; N/AAttention and memory are important parts of cognition that must be routinely examined in daily practice of psychiatry and neurology. Traditionally, their assessment has been done via anamnesis where the clinician simply asks the patient whether they are suffering from any cognitive difficulties in their daily lives. The present study investigated whether there is a significant association between the patient's simple anamnestic information about cognitive impairments and the scores in related subtests of Montreal Cognitive Assessment Test (MoCA). We found that there is a statistically significant correlation between the simple anamnestic information and the scores on the related subtests of the MoCA. These results suggest that patients can be quickly and accurately evaluated in terms of their attention and memory functions by using a basic "yes/no" question.