Researcher:
Şahin, Gizem Nur

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PhD Student

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Gizem Nur

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Şahin

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Şahin, Gizem Nur

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2014 - 2019162020 - 20226

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Researcher Of Publications: search.filters.isAuthorOfPublication.3c1f1845-7e8a-4225-80d0-ad2141105bcc

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Now showing 1 - 10 of 22
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    Construction of gel based 3D endometrial co -culture systems: can human mesenchymal stem cells be an alternative?
    (Oxford Univ Press, 2017) Yücel, D.; N/A; Karahüseyinoğlu, Serçin; Şahin, Gizem Nur; Şevgin, Kübra; Kocabay, Ahmet; Taşkın, Ali Cihan; Faculty Member; Master Student; PhD Student; Other; Other; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; Graduate School of Health Sciences; Graduate School of Health Sciences; N/A; N/A; 110772; N/A; N/A; N/A; 291296
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    Polymeric and collagen biomaterials enhance implantation of mouse blastocysts in three-dimensional culture models
    (Elsevier, 2021) Başoz, Deniz; Yücel, Deniz; N/A; N/A; N/A; N/A; N/A; Department of Industrial Engineering; N/A; Ergün, Yağmur; Şahin, Gizem Nur; Şevgin, Kübra; Kocabay, Ahmet; Taşkın, Ali Cihan; Gönen, Mehmet; Karahüseyinoğlu, Serçin; PhD Student; PhD Student; PhD Student; Other; Other; Faculty Member; Faculty Member; Department of Industrial Engineering; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); Graduate School of Health Sciences; Graduate School of Health Sciences; Graduate School of Health Sciences; N/A; N/A; College of Engineering; School of Medicine; N/A; N/A; N/A; N/A; 291296; 237468; 110772
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    Celcular and molecular dynamics of in-vitro 2D and 3D cultured blastocysts throughout the implantation process
    (Amer Soc Cell Biology, 2016) Yucel, D.; N/A; Karahüseyinoğlu, Serçin; Şahin, Gizem Nur; Kocabay, Ahmet; Taşkın, Ali Cihan; Faculty Member; PhD Student; Other; Other; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; Graduate School of Health Sciences; N/A; N/A; N/A; N/A; N/A; Koç University Hospital; 110772; N/A; N/A; 291296
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    Gonadotoxic chemotherapy agents impact ovarian stroma and vasculature
    (Oxford Univ Press, 2015) N/A; N/A; N/A; Şahin, Gizem Nur; Karahüseyinoğlu, Serçin; Öktem, Özgür; PhD Student; Faculty Member; Faculty Member; Graduate School of Health Sciences; School of Medicine; School of Medicine; N/A; 110772; 102627
    Cancer is a major public health problem around the world. Currently, about 5% of women diagnosed with cancer are of reproductive age. These young survivors may face compromised fertility. The effects of chemotherapeutic agents on ovarian reserve and its clinical consequences are generally inferred from a variety of surrogate markers of ovarian reserve, all aiming to provide prognostic information on fertility or the likelihood of success of infertility treatment. Until recently, the mechanisms that are responsible for chemotherapy-induced ovarian damage were not fully elucidated. The understanding of these mechanisms may lead to targeted treatments to preserve fertility. In this manuscript, we will review the current knowledge on the mechanism of ovarian damage and clinical impact of chemotherapy agents on fertility.
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    Antimetabolite cancer drug gemcitabine selectively impacts preantral and antral follicle cohorts in the ovary as evidenced by quantitatively histomorphometric, hormonal and cell viability markers
    (Oxford Univ Press, 2014) N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Kılıç, Yağmur; Şahin, Gizem Nur; Karanfil, Işıl; Eryılmaz, Baldan; Yılmaz, Pelinsu; Özkanbaş, Necmettin Can; Öktem, Özgür; Undergraduate Student; PhD Student; Undergraduate Student; Undergraduate Student; Undergraduate Student; Undergraduate Student; Faculty Member; School of Medicine; Graduate School of Health Sciences; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; N/A; 102627
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    Use of polymeric cell carriers supplemented with endometrial co-culture systems to enhance blastocyst implantation
    (Amer Soc Cell Biology, 2015) Yücel, Deniz; Köse, Ayça; N/A; Karahüseyinoğlu, Serçin; Şahin, Gizem Nur; Taşkın, Ali Cihan; Okan, Türkan Pemra; Öktem, Özgür; Faculty Member; PhD Student; Other; N/A; Undergraduate Student; Faculty Member; School of Medicine; Graduate School of Health Sciences; N/A; N/A; School of Medicine; School of Medicine; 110772; N/A; 291296; N/A; N/A; 102627
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    Combination of epigenetic enzyme inhibitors, gsk-j4 and belinostat, reveals high efficacy in idh1 mutant gliomas
    (N/A, 2020) Wakimoto, Hiroaki; Cahill, Daniel; Cribbs, Adam; Oppermann, Udo; N/A; Kayabölen, Alişan; Şahin, Gizem Nur; Şeker-Polat, Fidan; Cingöz, Ahmet; Işık, Bekir; Acar, Simge; Solaroğlu, İhsan; Önder, Tuğba Bağcı; PhD Student; PhD Student; PhD Student; Researcher; Undergraduate Student; Undergraduate Student; Faculty Member; Faculty Member; Graduate School of Health Sciences; Graduate School of Health Sciences; Graduate School of Health Sciences; Graduate School of Health Sciences; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; N/A; 102059; 184359
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    Targeting c-Jun N-terminal kinase (JNK) pathway in granulosa cell tumor of the ovary: translating the findings from reproductive biology into cancer biology
    (Sage Publications Inc, 2014) Güzel, Yılmaz; N/A; N/A; N/A; N/A; N/A; Şenbabaoğlu, Filiz; Lack, Nathan Alan; Şahin, Gizem Nur; Urman, Cumhur Bülent; Öktem, Özgür; PhD Student; Faculty Member; PhD Student; Faculty Member; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); Graduate School of Health Sciences; School of Medicine; Graduate School of Health Sciences; School of Medicine; School of Medicine; Koç University Hospital; N/A; 120842; N/A; 12147; 102627
    Nanoparticles have become popular photosensitizers for photothermal therapy (PTT), as they can be targeted to specific cancer tissues and deliver a chemotherapeutic drug, providing a multimodal therapeutic approach. Photothermal conversion efficiency of nanoparticles is critical in the assessment of their therapeutic use in PTT. We describe an accurate calorimetric method for the determination of the photothermal conversion efficiency of nanoparticles in solution. A tightly focused laser beam was used to irradiate a cuvette containing a solution of silver sulfide-glutathione quantum dots (Ag2S-GSH QDs), and the maximum steady-state temperature rise was measured with an infrared camera. The data were analyzed using two different photothermal conversion efficiencies, the intrinsic and external conversion efficiencies, to relate the induced heating power of the nanoparticles to the absorbed and incident optical powers, respectively. Measurements with a tunable Ti3+:sapphire laser showed that the intrinsic photothermal conversion efficiency of Ag(2)SGSH QDs exceeded 91% over the 720-810 nm wavelength range. The method was also used to analyze poly(acrylic acid)-coated superparamagnetic iron oxide nanoparticles (PAA/SPIONs), and the intrinsic photothermal conversion efficiency was determined to be 83.4% at 810 nm. This approach is useful for the evaluation of various potential nanoparticles for photothermal therapy applications.
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    Effects of methyl-beta-cyclodextrin on blood-brain barrier permeability in acute hypertension induced by angiotensin-II
    (Wiley, 2017) Yılmaz, Canan Uğur; Orhan, Nurcan; Arican, Nadir; Ahishali, Bülent; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Atış, Müge; Akcan, Uğur; Düzgün, Poyraz; Ceylan, Umut Deniz; Karahüseyinoğlu, Serçin; Şahin, Gizem Nur; Kaya, Mehmet; PhD Student; PhD Student; Undergraduate Student; Undergraduate Student; Faculty Member; PhD Student; Faculty Member; Graduate School of Health Sciences; Graduate School of Health Sciences; School of Medicine; School of Medicine; School of Medicine; Graduate School of Health Sciences; School of Medicine; 346431; N/A; N/A; N/A; 110772; N/A; 10486
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    Celcular and molecular dynamics of in-vitro 2D and 3D cultured blastocysts throughout the implantation process
    (Amer Soc Cell Biology, 2016) Yucel, D.; N/A; Karahüseyinoğlu, Serçin; Şahin, Gizem Nur; Kocabay, Ahmet; Taşkın, Ali Cihan; Faculty Member; PhD Student; Other; Other; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; Graduate School of Health Sciences; N/A; N/A; N/A; N/A; N/A; Koç University Hospital; 110772; N/A; N/A; 291296
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