Researcher:
Uyan, Zeynep Seda

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Faculty Member

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Zeynep Seda

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Uyan

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Uyan, Zeynep Seda

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Now showing 1 - 9 of 9
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    Publication
    Respiratory function in children with nephrotic syndrome: comparative evaluation of impulse oscillometry and spirometry
    (Wiley, 2021) Kilci, Fatih; Celakil, Mehtap E.; Dogan, Kenan; Bek, Kenan; Uyan, Zeynep Seda; Faculty Member; School of Medicine; 153502
    Aim: To evaluate the respiratory functions of children with nephrotic syndrome (NS) by impulse oscillometry (IOS) and its correlation with spirometry. Methods: Fifty-five NS patients aged 3-18 years were included as the study group and 40 healthy children of the same age formed the control group. Patients were divided into nephrotic phase (first attack and relapse) and remission. Demographic, anthropometric, and laboratory data of the children were recorded. Respiratory functions were evaluated by IOS and spirometry. Children over 6-years old performed both IOS and spirometry while children under 6 years performed only IOS. Results: The R (R5%, R10%, R5-20), AX and Z5% values of IOS in patients with nephrotic phase were higher than remission patients and control group while spirometry indices of PEF% and MEF25-75% were lower. Z scores of MEF25-75 were significantly negatively correlated with z scores of R5, R10, Z5, and Fres while they were significantly positively correlated with z scores of X values (5, 10, 15, and 20 Hz). Z scores of forced expiratory volume in 1 /forced vital capacity significantly negatively correlated with z scores of R values (R5, R10), Z5 and AX and positively correlated with z scores of X values (X5, X10, X15 Hz). Conclusion: Our study demonstrated that respiratory functions measured by IOS and spirometry were affected at the time of nephrotic phase in NS patients. IOS, a novel method easily applicable even in small children, is a potentially valuable tool to detect this condition; given its good correlation with spirometry.
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    Pediatric flexible bronchoscopy in the intensive care unit: a multicenter study
    (Wiley, 2021) Atag, Emine; Unal, Fusun; Yazan, Hakan; Girit, Saniye; Ergenekon, Almala Pinar; Yayla, Esra; Mertturk, Edanur; Telhan, Leyla; Meral, Ozge; Kucuk, Hanife Busra; Gunduz, Mehmet; Gokdemir, Yasemin; Eralp, Ela Erdem; Kiyan, Gursu; Cakir, Erkan; Ersu, Refika; Karakoc, Fazilet; Oktem, Sedat; Uyan, Zeynep Seda; Faculty Member; School of Medicine; 153502
    Introduction: Flexible bronchoscopy (FB) is frequently used for assessment and treatment of patients with respiratory diseases. Our aim was to investigate the contribution of FB to diagnosis and therapy in children admitted to the intensive care units (ICU) and to evaluate the safety of FB in this vulnerable population. Methods: Children less than 18 years of age who underwent FB in the five neonatal and pediatric ICUs in Istanbul between July 1st, 2015 and July 1st, 2020 were included to the study. Demographic and clinical data including bronchoscopy indications, findings, complications, and the contribution of bronchoscopy to the management were retrospectively reviewed. Results: One hundred and ninety-six patients were included to the study. The median age was 5 months (range 0.3-205 months). The most common indication of FB was extubation failure (38.3%), followed by suspected airway disease. Bronchoscopic assessments revealed at least one abnormality in 90.8% patients. The most common findings were airway malacia and the presence of excessive airway secretions (47.4% and 35.7%, respectively). Positive contribution of FB was identified in 87.2% of the patients. FB had greater than 1 positive contribution in 138 patients and 80.6% of the patients received a new diagnosis. Medical therapy was modified after the procedure in 39.8% and surgical interventions were pursued in 40% of the patients. Therapeutic lavage was achieved in 18.9%. There were no major complications. Conclusion: Flexible bronchoscopy is a valuable diagnostic and therapeutic tool in neonatal and pediatric ICUs and is not associated with major complications.
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    The effect of training the health care providers with simulation model on the care of patients with chronic tracheostomy
    (European Respiratory Society (ERS), 2021) Atag, Emine; Ergenekon, Almala Pinar; Gokdemir, Yasemin; Ay, Pinar; Ikizoglu, Nilay Bas; Cenk, Muruvvet; Eralp, Ela Erdem; Girit, Saniye; Cakir, Erkan; Kilic, Ayse Ayzit; Yazan, Hakan; Oksay, Sinem Can; Hepkaya, Evrim; Karadag, Bulent; Karakoc, Fazilet; Oktem, Sedat; Uyan, Zeynep Seda; Gökler, Ozan; Sivrikaya, Ulufer G.; Faculty Member; Teaching Faculty; Other; School of Medicine; School of Medicine; School of Medicine; 153502; 311179; N/A
    Introduction: Tracheostomy care in children may be challenging, due to lack of knowledge of health care providers. The aim of this study was to determine the level of knowledge of health care providers who follow patients with tracheostomy and to increase this level with theoretical education and training in a simulation laboratory. Materials and Methods: Volunteer participants were subjected to a theoretical pretest which evaluated their knowledge level for the care, follow-up and treatment of patients with tracheostomy. Then, practical testing with three subheadings evaluating the change of the tracheostomy cannula was applied. After theoretical training and one-on-one practical training given to the participants with a simulation model, theoretical and practical posttests were applied. Results: Fifty-one health care providers from six tertiary pediatric clinics in Istanbul were enrolled in the educational course. Only 6 (11.8%) of them received standardised training programme previously. Regarding the theoretical tests, seven of the 33 questions were indicated as crucial. The knowledge level of the participants based on the crucial questions significantly increased after the training (p value <0.05 for all of the crucial questions). Total number of correct answers and correct answers of 3 subheadings also significantly increased after the practical training (p value <0.001 for all). Ninety-five percent of the participants assessed the course as good or excellent. Conclusion: Training in simulation laboratory together with theoratical education can improve the knowledge and skills of the health care providers enabling improved care of children with tracheostomy.
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    Home mechanical ventilation in children: the experience of pediatric pulmonology divisions in Istanbul
    (European Respiratory Society (ERS), 2022) Yanaz, M.; Unal, F.; Hepkaya, E.; Yazan, H.; Oksay, S. Can; Yegit, C. Yilmaz; Baskan, A. Kilic; Onay, Z. R.; Gulieva, A.; Soyyigit, A.; Kalyoncu, M.; Kucuk, H. B.; Ayhan, Y.; Ergenekon, A. P.; Atag, E.; Uzuner, S.; Ikizoglu, N. Bas; Kilinc, A. Ayzit; Ay, P.; Eralp, E. Erdem; Gokdemir, Y.; Oktem, S.; Cakir, E.; Girit, S.; Cokugras, H.; Ersu, R.; Karadag, B.; Karakoc, F.; N/A; Köstereli, Ebru; Uyan, Zeynep Seda; Researcher; Faculty Member; School of Medicine; School of Medicine; 153503; 153502
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    Efficacy of standardized tracheostomy training with a simulation model for healthcare providers: a study by ISPAT team
    (Wiley, 2022) Sivrikaya, Ulufer G.; Atag, Emine; Ergenekon, Almala P.; Gokdemir, Yasemin; Ay, Pinar; Ikizoglu, Nilay Bas; Cenk, Muruvvet; Eralp, Ela Erdem; Girit, Saniye; Cakir, Erkan; Kilic, Ayse A.; Yazan, Hakan; Oksay, Sinem Can; Hepkaya, Evrim; Kiyan, Gursu; Karadag, Bulent; Karakoc, Fazilet; Oktem, Sedat; Uyan, Zeynep Seda; Gökler, Ozan; Faculty Member; Teaching Faculty; School of Medicine; School of Medicine; 153502; 311179
    Introduction: Tracheostomy care in children may be challenging, due to lack of knowledge of healthcare providers (HCPs). The aim of this study was to determine the level of knowledge of HCP who follow patients with tracheostomy and to increase this level with theoretical training and training in a simulation laboratory. Materials and Methods: ISPAT (IStanbul PAediatric Tracheostomy), a multidisciplinary team for tracheostomy care was established and a training program was prepared. Participants were subjected to theoretical and practical pretests which evaluated their knowledge levels and skills for care, follow-up, and treatment of a patient with tracheostomy. After the theoretical and practical training given to the participants with a simulation model, theoretical and practical posttests were applied. Results: Fifty-one HCP from nine tertiary pediatric clinics in Istanbul were enrolled in the training program. Only six (11.8%) of them had received standardized training programs previously. Regarding the theoretical tests, seven of the 33 questions were indicated as essential. The knowledge level of the participants based on the essential questions significantly increased after the training (p < 0.05 for all of the essential questions). The total number of correct answers and correct answers of three subheadings also significantly increased after the practical training (p < 0.001 for all). Ninety-five percent of the participants assessed the course as good or excellent in general. Conclusion: Training in a simulation laboratory in combination with theoretical education can improve the knowledge and skills of the HCP enabling improved care of children with a tracheostomy.
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    The ISPAT project: implementation of a standardized training program for caregivers of children with tracheostomy
    (Wiley, 2022) Yegit, Cansu Yilmaz; Kilinc, Ayse Ayzit; Oksay, Sinem Can; Unal, Fusun; Yazan, Hakan; Gulieva, Aynur; Arslan, Huseyin; Uzuner, Selcuk; Onay, Zeynep Reyhan; Baskan, Azer Kilic; Collak, Abdulhamit; Atag, Emine; Ergenekon, Almala Pinar; Ikizoglu, Nilay Bas; Ay, Pinar; Oktem, Sedat; Gokdemir, Yasemin; Girit, Saniye; Cakir, Erkan; Cokugras, Haluk; Karadag, Bulent; Karakoc, Fazilet; Eralp, Ela Erdem; Uyan, Zeynep Seda; Köstereli, Ebru; Faculty Member; Researcher; School of Medicine; School of Medicine; 153502; 153503
    Background: Tracheostomy-related morbidity and mortality mainly occur due to decannulation, misplacement, or obstruction of the tube. A standardized training can improve the skills and confidence of the caregivers in tracheostomy care (TC). Objective: Our primary aim was to evaluate the efficiency of standardized training program on the knowledge and skills (changing-suctioning the tracheostomy tube) of the participants regarding TC. Materials and Methods: Sixty-five caregivers of children with tracheostomy were included. First, participants were evaluated with written test about TC and participated in the practical tests. Then, they were asked to participate in a standardized training session, including theoretical and practical parts. Baseline and postintervention assessments were compared through written and practical tests conducted on the same day. Results: A significant improvement was observed in the written test score after the training. The median number of correct answers of the written test including 23 questions increased 26%, from 12 to 18 (p < .001). The median number of correct steps in tracheostomy tube change (from 9 to 16 correct steps out of 16 steps, 44% increase) and suctioning the tracheostomy tube (from 9 to 17 correct steps out of 18 steps, 44% increase) also improved significantly after the training (p < .001, for both). Conclusion: Theoretical courses and practical hands-on-training (HOT) courses are highly effective in improving the practices in TC. A standardized training program including HOT should be implemented before discharge from the hospital. Still there is a need to assess the impact of the program on tracheostomy-related complications, morbidity, and mortality in the long term.
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    Evaluation of respiratory function of children with nephrotic syndrome by impulse oscillometry and spirometry
    (Springer, 2018) Kilci, Fatih; Celakil, Mehtap; Yucel, Burcu Bozkaya; Bek, Kenan; Uyan, Zeynep Seda; Faculty Member; School of Medicine; 153502
    N/A
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    Platypnea-orthodeoxia syndrome in a child: relief of symptoms after transcatheter closure of patent foramen ovale
    (Cambridge Univ Press, 2021) N/A; N/A; N/A; Çetiner, Nilüfer; Uyan, Zeynep Seda; Çeliker, Alpay; Faculty Member; Faculty Member; Other; School of Medicine; School of Medicine; School of Medicine; 181047; 153502; N/A
    Platypnea-orthodeoxia syndrome is a rare clinical entity characterised by positional dyspnoea and arterial desaturation while in the upright position, the symptoms generally occurring in adults. We describe a 12-year-old girl diagnosed with platypnea-orthodeoxia syndrome associated with patent foramen ovale. the symptoms resolved following percutaneous patent foramen ovale closure.
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    Effect of standardized hands-on-training in caregivers of children with tracheostomy
    (European Respiratory Society (ERS), 2021) Yegit, Cansu Yilmaz; Kilinc, Ayse Ayzit; Gulieva, Aynur; Atag, Emine; Yazan, Hakan; Oksay, Sinem Can; Uzuner, Selcuk; Onay, Zeynep Reyhan; Hepkaya, Evrim; Ergenekon, Almala Pinar; Kalyoncu, Mine; Unal, Fusun; Mavi, Deniz; Ayhan, Yetkin; Collak, Abdulhamit; Cenk, Muruvvet; Arslan, Huseyin; Baskan, Azer Kilic; Bilgin, Gulay; Ikizoglu, Nilay Bas; Ay, Pinar; Oktem, Sedat; Gokdemir, Yasemin; Cakir, Erkan; Girit, Saniye; Cokugras, Haluk; Karadag, Bulent; Karakoc, Fazilet; Eralp, Ela Erdem; N/A; Köstereli, Ebru; Uyan, Zeynep Seda; Researcher; Faculty Member; School of Medicine; School of Medicine; 153503; 153502
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