Researcher: Shabsog, Mohammed Kamal Yahya
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Shabsog, Mohammed Kamal Yahya
Shabsog, Moh'D Kamal
Shabsog, Moh'D Kamal
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Publication Metadata only Optimal location for eliciting the tibial H-reflex and motor response(Wiley, 2018) N/A; N/A; Özyurt, Mustafa Görkem; Shabsog, Mohammed Kamal Yahya; Dursun, Merve; Türker, Kemal Sıtkı; PhD Student; Undergraduate Student; Undergraduate Student; Faculty Member; Graduate School of Sciences and Engineering; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; 6741Introduction: Although there are numerous protocols to adjust the amplitude of the Hoffmann reflex (H-reflex) relative to the size of the direct motor response (M-response), the optimal stimulating location has not been described. We sought to determine the optimal positioning of the stimulating cathode when evoking the tibial nerve H-reflex and M-response. Methods: A small cathode was placed on defined points in the popliteal fossa while an anode was fixed on the patella. The tibial nerve was stimulated electrically, and the response of the soleus muscle was recorded using intramuscular and surface electromyography. Results: We found that more-lateral points along a line drawn across the popliteal fossa were the best locations to obtain only the M-response, whereas stimulating the midpoint was optimal for obtaining only the H-reflex. Discussion: By using specified locations for electrical stimulation to evoke H-reflex and M-response, the functionality of the tibial nerve can be assessed.Publication Metadata only Psychopathology and dissociation among boarding school students in eastern Turkey(Springer Heidelberg, 2021) N/A; N/A; Mutluer, Tuba; Fatih, Parmis; Tayakısı, Emre; Shabsog, Mohammed Kamal Yahya; Çapacı, Merve; Yürük, Deniz; Necef, Işıl; Faculty Member; Researcher; Undergraduate Student; Undergraduate Student; Undergraduate Student; Undergraduate Student; Doctor; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Koç University Hospital; 305311; N/A; N/A; N/A; N/A; N/A; N/AA subset of boarding schools for adolescents was established in 1993 in the rural sections of Eastern Turkey to provide equity in terms of availability of education. Even though these schools were beneficial in many respects, implementation of this institutional model gave rise to many challenges such as weaker relationships with parents and defiance of authority figures. Failure to develop a mature response to these challenges could lead to the development of psychopathologies such as depression, psychosis, and dissociation. The main objective of this study is to assess the incidence of psychopathology and dissociative experiences of the residential female students in the regional boarding schools compared to a control group. 187 female participants, 128 attending boarding school, and 59 attending day school, as the control group, were included in the study. Brief Symptom Inventory (BSI) and Adolescent Dissociative Experiences Scale (ADES) were used as measurement scales. T-test, Mann Whitney-U, Spearman correlation chi-square tests were used to evaluate the association between the variables. There was a significant difference in Interpersonal sensitivity and Psychoticism subscales of BSI. ADES score was found to be significantly higher in the Boarding school group. Boarding school students are at a higher risk of developing psychopathology as a common trauma on a group of people can result in shared dissociation, a collective defense mechanism to cope with the injury, which resembles shared delusional disorder within DSM-V (The Diagnostic and Statistical Manual of Mental Disorders). Screening measures should be implemented in boarding schools to evaluate adolescents for psychopathology and preventive measures should be taken to intervene in the early stages.Publication Metadata only Assessment of the corticospinal fiber integrity in mirror movement disorder(Elsevier, 2018) Solmaz, Bilgehan; Akçimen, Fulya; Dalçık, Hakkı; Algın, Oktay; Başak, Ayşe Nazlı; Çavdar, Safiye; Özyurt, Mustafa Görkem; Shabsog, Mohammed Kamal Yahya; Türker, Kemal Sıtkı; Demir, Ata Berk; Özgür, Merve; Faculty Member; PhD Student; Undergraduate Student; Faculty Member; PhD Student; PhD Student; School of Medicine; Graduate School of Sciences and Engineering; School of Medicine; School of Medicine; Graduate School of Health Sciences; Graduate School of Health Sciences; 1995; N/A; N/A; 6741; N/A; 197462Mirror movements are unintended movements occurring on one side of the body that mirror the contralateral voluntary ones. It has been proposed that mirror movements occur due to abnormal decussation of the corticospinal pathways. Using detailed multidisciplinary approach, we aimed to enlighten the detailed mechanism underlying the mirror movements in a case subject who is diagnosed with mirror movements of the hands and we compared the findings with the unaffected control subjects. To evaluate the characteristics of mirror movements, we used several techniques including whole exome sequencing, computed tomography, diffusion tensor imaging and transcranial magnetic stimulation. Computed tomography showed the absence of a spinous process of C5, fusion of the body of C5-C6 vertebrae, hypoplastic dens and platybasia of the posterior cranial fossa. A syrinx cavity was present between levels C3-C4 of the spinal cord. Diffusion tensor imaging of the corticospinal fibers showed disorganization and minimal decussations at the lower medulla oblongata. Transcranial magnetic stimulation showed that motor commands were distributed to the motor neuron pools on the left and right sides of the spinal cord via fast-conducting corticospinal tract fibers. Moreover, a heterozygous missense variation in the deleted in colorectal carcinoma gene has been observed. Developmental absence of the axonal guidance molecules or their receptors may result in abnormalities in the leading of the corticospinal fibers. Clinical evaluations and basic neuroscience techniques, in this case, provide information for this rare disease and contribute to our understanding of the normal physiology of bimanual coordination. (C) 2018 Elsevier Ltd. All rights reserved.Publication Metadata only Manual separation, topical vaseline and estrogen in labial adhesions(Logos Medical Publishing, 2019) N/A; N/A; Özen, Mehmet Ali; Aydın, Emrah; Eroğlu, Egemen; Shabsog, Mohammed Kamal Yahya; Oğuzkurt, Nigar Pelin; Faculty Member; Faculty Member; Faculty Member; Undergraduate Student; Doctor; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; Koç University Hospital; 293404; 32059; 214688; N/A; N/AObjective: Although labial adhesions are frequently seen in childhood, debates are continuing about its pathophysiology and management. Despite topical estrogen is the most preferred treatment option, there are different opinions about its efficacy and side effects. Herein, we aimed to compare the effectiveness of combined treatments and manual separation and their long-term recurrence rates. Method: All primary cases diagnosed with complete labial adhesion between 2014 and 2019 and followed up for at least 6 months were analyzed per age, admission complaints, recurrence and side effects. Study groups were determined as; MS (Group 1); MS and pure vaseline (Group 2); MS and topical estrogen (Group 3). Results: Ninety-eight patients with median age of 2.6 years (range 4 to 108 months) who met the study criteria were included in the study. While itching, erythema, post-void dripping and urinary infection were the most common symptoms at presentation, 28.5% of the patients were diagnosed during routine examination and 17.3% of the cases diagnosed by the families as closed vagina. Group 1 had 30 (30.61%), Group 2, 39 (39.80%) and Group 3 29 (29.60%) patients. The recurrence rates were 23.3%, 2.5%, and 6.8%, respectively. Side effects were seen only in MS and topical estrogen-treated group (4 children). Conclusion: Treatment with MS and pure vaseline has a lower recurrence rate without any side effects compared to the other two groups. It can be preferred safely in the treatment of complete labial adhesions. / GİRİŞ ve AMAÇ: Labial adezyon çocukluk çağında sık görülmesine rağmen, patofizyolojisi ve yönetimi hakkında tartışmalar mevcuttur. En sık tercih edilen tedavi seçeneği topikal östrojen olmakla beraber etkinliği ve yan etkileri hakkında farklı görüşler mevcuttur. Bu çalışmada manuel separasyon (MS) ile kombine yapılan tedavilerin etkinliğini ve uzun süredeki nüks oranlarını karşılaştırmayı amaçladık. YÖNTEM ve GEREÇLER: 2014 ve 2019 yılları arasında tam labial adezyon tanısı alan ve en az 6 ay süre ile takip edilen tüm birincil vakalar yaş, başvuru yakınması, nüks ve yan etkiler bakımından analiz edildi. Çalışma grupları; MS (Grup 1); MS ve saf vazelin (Grup 2); MS ve topikal östrojen (Grup 3), olarak belirlendi. BULGULAR: Kriterleri karşılayan 98 hasta çalışmaya dahil edildi. Hastaların ortanca yaşı 2,6 yıldı ( 4-108 ay). Grup 1 de 30 (%30,6), grup 2 de 39 (%39,8) ve grup 3 de 29 (%29,6) hasta mevcuttu. Kaşıntı, kızarıklık, işeme sonrası damlama, üriner enfeksiyon en sık başvuru semptomları iken, hastaların %28,5 inde tanı semptom olmadan rutin muayene esnasında, %17,3 ünde ise aileler tarafından tespit edilen vajen kapalılığı sonrasında konulmuştu. Nüks oranları grup 1 de %23,3, grup 2 de %2,5 ve grup 3 de ise %6,8 olarak tespit edildi. Sadece MS ve topikal östrojen uygulanan grupta, 4 çocukta yan etki görülmüştü. TARTIŞMA ve SONUÇ: MS ve saf vazelin tedavisi, diğer iki gruba göre herhangi bir yan etkisi olmadan daha düşük nüks oranına sahiptir. Bu sebeplerden dolayı labial adezyonların tedavisinde bu uygulamanın güvenle tercih edilebileceğini düşünmekteyiz.Publication Metadata only The overlooked association between lower urinary tract dysfunction and psychiatric disorders: a short screening test for clinical practice(Elsevier Sci Ltd, 2019) N/A; N/A; Özen, Mehmet Ali; Mutluer, Tuba; Necef, Işıl; Shabsog, Mohammed Kamal Yahya; Taşdemir, Mehmet; Bilge, İlmay; Eroğlu, Egemen; Faculty Member; Faculty Member; Faculty Member; Undergraduate Student; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; Koç University Hospital; Koç University Hospital; N/A; 293404; 305311; N/A; N/A; 175867; 198907; 214688Introduction Lower urinary tract dysfunction (LUTD) often presents with other associated comorbidities such as urinary tract infections, constipation, fecal incontinence, and vesicoureteral reflux. However, the psychiatric conditions that can be associated with LUTD tend to go unnoticed. The evaluation, diagnosis, and treatment of LUTD and psychiatric disorders in children are difficult and time-consuming. Moreover, there is currently no accepted consensus on this subject. Objective In this study, the authors aimed to investigate the relationship between the subgroups of both LUTD and psychiatric disorders. Study design LUTD were divided into 4 groups by using voiding dysfunction symptom score (VDSS), bladder diary, and uroflowmetry/electromyography (UF/EMG) test. A short screening test for psychological problems was used to detect psychiatric disorders accompanying each LUTD group. In terms of psychiatric disorders, the patients were divided into two groups: externalizing and internalizing disorders. Results A total of 156 children were diagnosed with LUTD. Seventy-six patients had overactive bladder (OAB), 53 had dysfunctional voiding (DV), 14 had primary bladder neck dysfunction (PBND), and 13 had underactive bladder (UAB). Psychiatric disorder was detected in 46 children (29.4%). Of these, 32 had an externalizing and 14 had an internalizing disorder. In terms of age, externalizing disorders were more common in children aged between 6 and 11 years (87.5%), whereas internalizing disorders were seen equally in both age groups. Among these, attention deficit hyperactivity disorder (ADHD) was the most common psychiatric disorder (16.1%). The LUTD groups with the most frequent psychiatric disorders were UAB (53.8%), PBND (35.7%), and OAB (28.9%). Discussion Most of the studies investigating the relationship between the lower urinary tract and psychiatric disorders so far have been concerned with the lower urinary tract symptom (LUTS) (such as nighttime or daytime incontinence) and ADHD. However, the present study was performed according to the LUTD classification, which is primarily based on VDSS, bladder diary, and UF/EMG tests. Furthermore, psychiatric disorders were classified into their subgroups. The results have shown that around a quarter of children with LUTD also had comorbid psychiatric disorders. The relationship between LUTD and psychiatric disorders constitutes a critical point. Identifying this association can contribute to the comprehensive diagnosis and treatment for these patients. Conclusions LUTD and psychiatric disorders can be seen together, and this can be detected by the short screening test for psychological problems. Therefore, the authors think that patients who applied with LUTS should undergo this short test along with the routine urinary system examination and tests.