Researcher:
Buluş, Eser

Profile Picture
ORCID

Job Title

Doctor

First Name

Eser

Last Name

Buluş

Name

Name Variants

Buluş, Eser

Email Address

Birth Date

Filters

20223

Advanced Search

Filter by

Settings

Researcher Of Publications: search.filters.isAuthorOfPublication.5b63a771-7fa3-4904-a556-8e59d450ac3f

Search Results

Now showing 1 - 3 of 3
  • Placeholder
    PublicationMetadata only
    The effect of cognitive tasks during electroencephalography recording in patients with reflex seizures
    (Sage Publications Inc, 2022) Abanoz, Yasin; Gülen Abanoz, Yeşim; Yeni, Seher Naz; N/A; Buluş, Eser; Doctor; School of Medicine; Koç University Hospital; N/A
    Objective We aimed to research the effect of cognitive tasks on interictal electroencephalographic (EEG) recordings in patients with epilepsy who had reported cognitive functions as a seizure trigger. We investigated the usefulness of cognitive function tasks as a method of activation in standard-awake EEG in daily practice. Methods Standard-awake EEG with cognitive activation tasks consisting of verbal and arithmetic tasks was administered to 35 (11.7%) of 299 patients with epilepsy who reported cognitive functions as a reflex seizure stimulus. During the background EEG, patients were divided into 2 groups: group 1 (17 patients) with interictal epileptiform discharges (IEDs), and group 2 (18 patients) without IEDs. Results IEDs were activated by a verbal task in 11.4% of patients and by an arithmetic task in 5.7%. All activated patients were in the genetic/idiopathic generalized epilepsy (IGE) group. In group 1, IEDs were activated in 17.6% of patients by a verbal task and in 5.9% by an arithmetic task. Both verbal and arithmetic tasks showed provocative effect in one patient in group 2. Hyperventilation was the most effective activation method, followed by cognitive activation tasks and photic stimulation. The provocative effects of verbal and arithmetic tasks were comparable to those of photic stimulation. Conclusion Cognitive tasks might activate the IEDs in patients reporting cognitive functions as a seizure trigger, particularly in IGE. Brief and standardized cognitive activation tasks should be developed and applied as a method of activation during standard-awake EEG recordings to increase the diagnostic yield of EEG.
  • Placeholder
    PublicationMetadata only
    The clinical use of impulse oscillometry in neuromuscular diseases
    (W. B. Saunders, 2022) Bayraktaroglu, Mesut; N/A; İliaz, Sinem; Yunisova, Gulshan; Çakmak, Özgür Öztop; Çelebi, Özlem; Buluş, Eser; Duman, Arda; Oflazer, Piraye; Doktor; Doktor; Faculty Member; Doktor; Doktor; Doktor; Faculty Member; N/A; N/A; School of Medicine; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; N/A; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; 299358; N/A; N/A; N/A; N/A
    Background: The patients with neuromuscular diseases (NMD) are very fragile and it is hard to evaluate respiratory involvement of the primary disease in this group. Therefore, our study aimed to reveal the relationship between pulmonary function tests (PFT) and impulse oscillometry (IOS) and their correlation with respiratory clinical findings in NMD. Material and methods: A total of 86 consecutive patients with NMD were included. The clinical findings of respiratory involvement, PFT, and IOS results of the patients were analyzed. Results: Forty patients out of 86 were female. There were 29 patients with amyotrophic lateral sclerosis, four patients with myasthenia gravis, and 53 patients with muscular dystrophies/myopathies. According to the PFT results, 47 patients had restrictive PFT. However, there was no difference in IOS parameters when we compared the patients according to restrictions in PFT. A positive correlation was found with FVC %pred and X-5. PEF % pred values were positively correlated with X-10, X-15, and X-20, and negatively correlated with A(X) and R5-20. The patients with worse swallowing capability had increased R-rs levels, and more negative X-rs levels. The shortness of breath led to lower FEV1 %pred., higher R-5, A(X) and R5-20, and also more negative X-10, X-15, and X-35. Conclusion: Clinically reported dysphagia, a decreased capability of coughing, and shortness of breath in patients with NMD make R-rs increase in general, but X-rs parameters, which mainly express rib cage elasticity, turn more negative. In patients with NMD, IOS monitoring may help in evaluating the regression in respiratory functions, however, future studies are needed to understand more.
  • Placeholder
    PublicationMetadata only
    A case with new-onset neuromyelitis optica spectrum disorder following COVID-19 mRNA BNT162b2 vaccination
    (Lippincott Williams & Wilkins, 2022) Afşar, Nazire; N/A; N/A; N/A; Çalışkan, İlay; Buluş, Eser; Polat-Altıntaş, Sevgi; Master Student; Doctor; Researcher; N/A; N/A; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); Graduate School of Health Sciences; School of Medicine; N/A; N/A; N/A; 150017
    Introduction: In the midst of the coronavirus disease of 2019 pandemic, active immunization by effective vaccination gained utmost importance in terms of global health. The messenger RNA (mRNA) vaccines are novel strategies requiring clinical surveillance for adverse events. Case Report: We report a 43-year-old previously healthy female with an optic neuritis attack 24 hours following immunization with the second dose of coronavirus disease of 2019 mRNA BNT162b2 vaccine. A second transverse myelitis attack together with an elevated anti-AQP-4 antibody titer confirmed the diagnosis of neuromyelitis optica spectrum disorder. Conclusion: Our case identifies the BNT162b2 vaccine as a possible trigger for neuromyelitis optica spectrum disorder. This rare and potentially coincidental event has no implications for vaccine administration practices. However, further research is needed to elucidate the effects of mRNA vaccines on humoral and cell-mediated immunity.