Researcher:
Sarıkaya, Ahmet Furkan

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Ahmet Furkan

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Sarıkaya

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Sarıkaya, Ahmet Furkan

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2021 - 20224

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    Fluorescence-guided extended pelvic lymphadenectomy during robotic radical prostatectomy
    (Springernature) N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Özkan, Arif; Köseoğlu, Ersin; Canda, Abdullah Erdem; Çil, Barbaros Erhan; Aykanat, İbrahim Can; Sarıkaya, Ahmet Furkan; Tarım, Kayhan; Armutlu, Ayşe; Kulaç, İbrahim; Barçın, Erinç; Falay, Fikri Okan; Kordan, Yakup; Baydar, Dilek Ertoy; Balbay, Mevlana Derya; Esen, Tarık; Doctor; Faculty Member; Faculty Member; Faculty Member; Doctor; Researcher; Researcher; Teaching Faculty; Faculty Member; Undergraduate Student; Teaching Faculty; Faculty Member; Faculty Member; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 350876; 116202; 169993; N/A; 327615; 327605; 133567; 170305; N/A; 246484; 157552; 8025; 153320; 50536
    We evaluated and described the impact of prostatic indocyanine green (ICG) injection on extended pelvic lymph node (LN) dissection (ePLND) in robotic-assisted radical prostatectomy (RARP). Between January 2019 and December 2021, we included consecutive 50 PCa patients who underwent ePLND during RARP with (n = 25) or without (n = 25) prostatic ICG injection. ICG injection was performed during abdominal port placement and robot docking. Pelvic LNs reflecting green color were initially excised and then the template was completed. The outcomes of two groups were compared. Overall, nine (36%) and five (20%) of the patients had metastatic LN involvement in the ICG and non-ICG groups, respectively. Of the 509 dissected LNs in the ICG group, 122 (23.9%) were fluorescence active. 20 LNs (3.9%) were metastatic in this group, 9 (45%) of which were ICG+. 408 LNs were resected on the non-ICG group with 8(1.9%) being metastatic. Eight (88.9%) of nine pN+ patients were florescent positive in the ICG group. Out of six patients with pN+ disease, Ga68 PSMA-PET/CT detected positive LNs preoperatively. In addition to preoperative Ga68 PSMA-PET/CT investigation, ICG-guided ePLND might increase identification and removal of metastatic LNs duirng RARP. Improvements in staging and oncologic outcomes may also be seen in intermediate- and high-risk patients.
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    Endopelvic fascia sparing robotic radical cystectomy with intracorporeal studer pouch with Balbay's technique
    (Society of Laparoscopic and Robotic Surgeons, 2022) Kilic, Mert; Musaoglu, Ahmet; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Balbay, Mevlana Derya; Köseoğlu, Ersin; Canda, Abdullah Erdem; Özkan, Arif; Kiremit, Murat Can; Tarım, Kayhan; Sarıkaya, Ahmet Furkan; Faculty Member; Faculty Member; Faculty Member; Doctor; Faculty Member; Researcher; Researcher; School of Medicine; School of Medicine; School of Medicine; N/A; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; 153320; 350876; 116202; 289255; 222920; 327605; 327615
    Background and Objectives: Robotic radical cystec-tomy (RARC) with intracorporeal urinary diversion is a technically complicated, time-consuming procedure. The aim of this study was to present the operative, pathologi-cal, oncological, and functional outcomes of patients who underwent endopelvic fascia sparing (EPFS) RARC with intracorporeal Studer pouch formation. To the best of our knowledge, this is first series in the literature that includes EPFS RARC.Methods: Between October 1, 2019 and April 30, 2022, 10 bladder cancer patients underwent EPFS RARC, bilat-eral extended pelvic lymph node dissection with intra-corporeal Studer pouch reconstruction with Balbay's technique. Patient demographics, operative, and post-operative parameters were recorded.Results: Among 10 patients, 8 were male and 2 were female. Mean operative time, median estimated blood loss, and median duration of hospital stay was 530 minutes, 316 ml, and 8 days, respectively. One month postoperatively, the mean maximum flow, average flow rate, mean voided, and post-voided urine volume were 20.2 ml/sec, 4.4 ml/sec, 273.6 ml, and 3.5 ml, respectively. All of the patients were fully continent during day-time, three had mild night-time incontinence requiring pad use (both patients 1 pad per night). During a mean 11.5 months of follow up, zero patients died. One patient with a pathological, stage 4 tumor, had nodal recurrence at six months postoperatively. No distant metastasis were detected. Conclusion: Endopelvic fascia sparing RARC has very promising early functional results with safe oncological outcomes and low complication rates.
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    Robotic partial nephrectomies with selective/superselective clamping of renal artery branch by using indocyanine green (icg)
    (Elsevier, 2022) Kılıç, M; N/A; Kordan, Yakup; Köseoğlu, Ersin; Sarıkaya, Ahmet Furkan; Tarım, Kayhan; Kiremit, Murat Can; Canda, Abdullah Erdem; Balbay, Mevlana Derya; Esen, Tarık; Özkan, Arif; Faculty Member; Faculty Member; Researcher; Researcher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Doctor; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Koç University Hospital; 157552; 350876; 327615; 327605; 222920; 116202; 153320; 50536; 289255
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    Preoperative prediction of lymph node invasion in prostate cancer: Ga-68 PSMA PET or nomograms?
    (Elsevier, 2021) Kılıç, M.; Musaoğlu, A.; N/A; Kordan, Yakup; Köseoğlu, Ersin; Sarıkaya, Ahmet Furkan; Tarım, Kayhan; Özkan, Alev; Kiremit, Murat Can; Acar, Ömer; Canda, Abdullah Erdem; Balbay, Mevlana Derya; Esen, Tarık; Faculty Member; Faculty Member; Researcher; Researcher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 157552; 350876; 327615; 327605; 12695; 222920; 237530; 116202; 153320; 50536
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    Ga-68-PSMA-11 positron emission tomography/computed tomography for primary lymph node staging before radical prostatectomy: central review of imaging and comparison with histopathology of extended lymphadenectomy
    (Elsevier, 2021) N/A; Esen, Tarık; Falay, Fikri Okan; Tarım, Kayhan; Armutlu, Ayşe; Köseoğlu, Ersin; Kılıç, Mert; Seymen, Hülya; Sarıkaya, Ahmet Furkan; Kiremit, Murat Can; Balbay, Mevlana Derya; Canda, Abdullah Erdem; Baydar, Dilek Ertoy; Kordan, Yakup; Demirkol, Mehmet Onur; Tilki, Derya; Faculty Member; Teaching Faculty; Researcher; Teaching Faculty; Faculty Member; Doctor; Teaching Faculty; Resaercher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Other; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; 50536; 246484; 327605; 133567; 350876; N/A; 350778; 327615; 222920; 153320; 116202; 8025; 157552; 196946; N/A
    Background: Results from prospective trials have shown higher accuracy of prostate-specific membrane antigen (PSMA)-based positron emission tomography (PET)/computed tomography (CT) in detection of lymph node metastasis (LNM) compared to conventional imaging. Objective: To evaluate the accuracy of Ga-68-PSMA-11 PET/CT for LNM detection in patients undergoing radical prostatectomy (RP) and extended pelvic lymph node dissection (PLND). Design, setting, and participants: Between June 2014 and November 2020, 96 patients with Ga-68-PSMA PET/CT for primary staging underwent RP and extended PLND. Outcome measurements and statistical analysis: The results from Ga-68-PSMA PET/CT were compared with histologic data from primary PLND in 96 patients. All Ga-68-PSMA PET/CT scans were centrally reviewed. Results and limitations: Of 96 patients, 15.6% (n = 15) harbored LNMs. The median prostate-specific antigen at Ga-68-PSMA PET/CT was 8.0 ng/ml (interquartile range 5.5-11.7). The majority of patients had intermediate- (52.1%) or high-risk disease (41.7%). Biopsy grade group 4 and 5 was present in 22.9% and 15.6%, respectively. The Ga-68-PSMA PET/CT scans identified eight of 15 patients (53.3%) as LN-positive (true positive). The calculated per-patient sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of Ga-68-PSMA PET/CT in the detection of LNM were 53.3%, 98.8%, 88.9%, 92.0%, and 91.7%, respectively. The per-patient sensitivity and specificity in the detection of LNMs larger than 2 mm were 61.5% and 98.8%, respectively. The main limitation is the retrospective design of the study. Conclusions: Ga-68-PSMA PET/CT is accurate in lymph node staging and the results support its use for primary staging of prostate cancer. Patient summary: We compared prostate-specific membrane antigen (PSMA)-based positron emission tomography (PET)/computed tomography (CT) findings with histopathology results after extended lymph node dissection and showed that it is accurate in detecting lymph node metastases. Our results support the use of PSMA PET/CT for primary staging of prostate cancer. (C) 2021 European Association of Urology. Published by Elsevier B.V. All rights reserved.