Researcher:
Karataş, Ferhan

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Doctor

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Ferhan

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Karataş

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Karataş, Ferhan

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2020 - 20213

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Researcher Of Publications: search.filters.isAuthorOfPublication.823c75ba-461e-464d-a817-34d1a11a1ac6

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    PublicationOpen Access
    Bronchoscopy during the COVID-19 Pandemic: a survey study
    (Bayçınar Tıbbi Yayıncılık ve Reklam Hizmetleri, 2021) Çağlayan, Benan Niku; Öztürk, Ayşe Bilge; Karataş, Ferhan; İliaz, Sinem; Uzel, Fatma Işıl; Faculty Member; Doctor; Doctor; School of Medicine; Koç University Hospital; 230719; 147629; N/A; 168584; N/A; N/A
    Background: in this study, we aimed to evaluate the attitudes and behaviors of physicians performing bronchoscopy during the COVID-19 outbreak. Methods: between March 2020 and May 2020, a total of 153 physicians were included in the study. An invitation letter for the participation in the study with a structured questionnaire of 18 questions were sent to the mail groups twice with five-day intervals. Participation in the study was allowed, until the third day after the second mail was sent. Results: all participants completed the questionnaire. According to the results, 33% of the physicians did not perform bronchoscopy and the majority of the physicians performed very few procedures during the outbreak, although the participants mostly worked at the tertiary hospitals (mean: 7.2±9.3). A total of 20% of the physicians performed bronchoscopy in potential or proven COVID-19 patients. Almost all of the physicians who participated in the survey reported the use of personal protective equipment such as masks and goggles during the procedure. During the pandemic, 9.7% of the physicians who performed bronchoscopy to potential or proven COVID-19 patients and 4.1% of the participants who did not perform bronchoscopy to any potential or proven COVID-19 patients were found to be infected with the virus (p>0.05). Conclusion: physicians who perform bronchoscopy during pandemic act in accordance with the recommendations of guidelines. Although there was no statistically significant difference between the SARS-CoV-2 transmission rates of the teams who performed and did not perform bronchoscopy in potential or proven COVID-19 patients in our study, the high rate of personal protective equipment utilization might have played a role in this result. / Amaç: bu çalışmada, COVID-19 salgını sırasında bronkoskopi yapan hekimlerin tutum ve davranışları değerlendirildi. Ça¬lış¬ma pla¬nı: Mart 2020 - Mayıs 2020 tarihleri arasında, toplam 153 hekim çalışmaya alındı. Mail gruplarına beş gün aralıklarla iki kere 18 sorudan oluşan yapılandırılmış anket ile katılım davet mektubu gönderildi. İkinci mail gönderiminden sonra üçüncü güne kadar çalışmaya katılıma izin verildi. Bulgular: katılımcıların tümü anketi tamamladı. Sonuçlara göre, katılımcılar büyük ölçüde üçüncü basamak hastanelerde çalışmakla birlikte, hekimlerin %33’ü salgın sırasında bronkoskopi yapmadı ve büyük bir çoğunluğu çok az sayıda işlem yaptı (ort. 7.2±9.3). Hekimlerin toplam %20’si, olası veya kesin COVID-19 hastalarına bronkoskopi yaptı. Ankete katılan hekimlerin neredeyse tamamı, işlem sırasında maske ve gözlük gibi kişisel koruyucu ekipman kullandığını bildirdi. Pandemi sırasında olası veya kesin COVID-19 hastalarına bronkoskopi yapan hekimlerin %9.7’si ve olası veya kesin COVID-19 hastalarının hiçbirine bronkoskopi yapmayan hekimlerin %4.1’inin virüs ile enfekte olduğu saptandı (p>0.05). So¬nuç: bronkoskopi yapan hekimler, salgın sırasında kılavuz önerilerine uygun bir biçimde hareket etmektedir. Çalışmamızda olası veya kesin COVID-19 hastalarına bronkoskopi yapan ve yapmayan hekimlerin ekiplerindeki SARS-CoV-2 bulaş oranları istatistiksel olarak anlamlı düzeyde farklı olmamakla birlikte, kişisel koruyucu ekipman kullanımının bu sonuçlarda rol oynadığı düşünülmektedir.
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    PublicationOpen Access
    COVID-19 pneumonia and idiopathic pulmonary fibrosis: a novel combination
    (Aves, 2020) Uzel, Fatma Işıl; İliaz, Sinem; Karataş, Ferhan; Çağlayan, Benan Niku; Doctor; Doctor; Doctor; Faculty Member; School of Medicine; Koç University Hospital; N/A; 168584; N/A; N/A
    Coronavirus disease 2019 (COVID-19) has become a game changer in many aspects of clinical practice. Acute exacerbations of idio-pathic pulmonary fibrosis (IPF) are known as serious events, which can reach a mortality rate of 50%, where viral infections may play a role. We describe the case of a 64-year-old male patient with a diagnosis of IPF under antifibrotic treatment for 1 year; the patient tested positive for COVID-19 with polymerase chain reaction test of the nasopharyngeal swab, and his chest computed tomography results were compatible with COVID-19 pneumonia described in the literature as well as the findings compatible with interstitial lung disease. The patient was successfully treated in the pulmonology ward according to official guidelines about COVID-19 along with antifibrotic treatment and required only a short course of oxygen therapy. We experienced no drug interactions, serious side effects, or complications during treatment. The patient was discharged after 1 week, and he is still in a good condition after 3 weeks. COVID-19 pneumonia in a patient with IPF who survived under antifibrotic treatment without serious deterioration is a new experience. Such cases will probably change our perspective in treating patients with IPF.
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    PublicationOpen Access
    Effect of high-risk Obstructive sleep apnea on clinical outcomes in adults with Coronavirus Disease 2019: a multicenter, prospective, observational cohort study
    (American Thoracic Society (ATS), 2021) Işık, Sacide Rana; Balcan, Baran; Çetin, Betül; OSACOVID-19 Study Collaborators; Ertuğ, Elif; Peker, Yüksel; Çelik, Yeliz; Arbatlı, Semih; Baygül, Arzu Eden; Yazıcı, Duygu; Bayram, Hasan; Karataş, Ferhan; Uzel, Fatma Işıl; İliaz, Sinem; Tabak, Levent; Öztürk, Ayşe Bilge; Atasoy, Kayhan Çetin; Kapmaz, Mahir; Durmaz Çetin, Birsen; Çağlayan, Benan Niku; Faculty Member; Researcher; PhD Student; PhD Student; Faculty Member; Doctor; Doctor; Doctor; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; Graduate School of Health Sciences; Koç University Hospital; 234103; N/A; N/A; 272290; N/A; 4890; N/A; N/A; 168584; N/A; 147629; N/A; N/A; 111719; 230719
    Rationale: obstructive sleep apnea (OSA) may contribute to poor outcomes in adults with Coronavirus Disease 2019 (COVID-19). Objective: to determine the effect of OSA on clinical outcomes in patients with COVID-19. Methods: the current prospective observational study was conducted in three hospitals in Istanbul, Turkey from March 10 to June 22, 2020. The participants were categorized as modified high-risk (mHR), or low-risk (mLR)-OSA according to a modified version of the Berlin questionnaire. Snoring patterns (intensity and/or frequency), breathing pauses and morning/daytime sleepiness, without taking obesity and hypertension into account, were used in the regression models. Results: the primary outcome was clinical improvement defined as a decline of 2 categories from admission on a 7-category ordinal scale. Secondary outcomes included worsening (increase of 1 category), need for hospitalization, supplemental oxygen and intensive care. In total, 320 eligible patients were enrolled. According to the modified scoring, 70 (21.9%) had mHR-OSA. Among 242 patients requiring hospitalization, clinical improvement within 2 weeks occurred in 75.4 % of the mHR-OSA group compared to 88.4 % of the modified low-risk (mLR-OSA) group (P = 0.014). In multivariate regression analyses, mHR-OSA (adjusted OR 0.42; 95% CI 0.19-0.92) predicted the delayed clinical improvement. In the entire study population (n=320), mHR-OSA was associated with clinical worsening and need for supplemental oxygen. Snoring patterns, especially louder snoring, were significantly predicted delayed clinical improvement, worsening, need for hospitalization, supplemental oxygen, and intensive care. Conclusions: adults with mHR-OSA in our Covid-19 cohort had poorer clinical outcomes than those with mLR OSA independent of age, sex and comorbidities.