Researcher:
Uygur, Halil Şafak

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Doctor

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Halil Şafak

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Uygur

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Uygur, Halil Şafak

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2013 - 20176

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Researcher Of Publications: search.filters.isAuthorOfPublication.83e4830b-e0dd-4595-bf55-a56ce55340aa

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    Setup of columellar height with costal cartilage graft modification in a patient with binder syndrome
    (European Society of Plastic, Reconstructive and Aesthetic Surgery, 2016) Aral, Mübin; Küçüker, İsmail; Uygur, Halil Şafak; Sezgin, Billur; Özmen, Selahattin; Doctor; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; Koç University Hospital; N/A; 133762; 125951
    Binder syndrome is an uncommon disorder of unknown etiology. It is characterized by hypoplasia of the nose and maxilla and altered morphology of the associated soft tissue. We present a surgical technique for setting up the columellar height in a patient with Binder syndrome. / Binder sendromu, etiyolojisi tam olarak bilinmeyen nadir bir bozukluktur. Burun-maksiller hipoplazi ve eşlik eden yumuşak doku anomalileriyle karakterizedir. Bu çalışmada Binder sendromlu bir olguda kolumellar yüksekliğin ayarlanmasında kullandığımız cerrahi teknik sunulmaktadır.
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    Nasal septum perforation repair using a split septal cartilage graft
    (Lippincott Williams & Wilkins, 2015) Aral, Mubin; Kandal, Sebahattin; Ayhan, Suhan; Uygur, Halil Şafak; Doctor; School of Medicine; Koc University Hospital; N/A
    N/A
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    Comparison of resorbable mesh (Poly L-lactide/Glycolic acid) and porous polyethylene in orbital floor fractures in an experimental model
    (Sage, 2017) Aral, Ali Mubin; Kaya, Basar; Coskun, Neslihan; Omeroglu, Suna; Kilic, Koray; N/A; Özmen, Selahattin; Uygur, Halil Şafak; Faculty Member; Doctor; School of Medicine; N/A; N/A; Koç University Hospital; 125951; N/A
    Background: Resorbable mesh and porous polyethylene are frequently used alloplastic materials for the treatment of the orbital blowout fractures. The literature lacks reports comparing their long-term effects on experimental models. Objective: Our aim was to radiologically and histologically evaluate the effectiveness and safety of porous polyethylene and resorbable mesh in a rabbit orbital blowout fracture model. Methods: Twelve New Zealand white rabbits (24 orbits) were randomized to 4 groups. In group 1, only orbital floor dissection was done. In group 2, following orbital floor dissection, a 10-mm defect was created without any extra procedure. In group 3, following a 10-mm defect creation, a 12-mm-round cut porous polyethylene was placed on the defect. In group 4, following a 10-mm defect creation, a 12-mm-round cut resorbable mesh was placed on the defect. Computed tomographic analysis was performed during follow-up period. Orbital floors were evaluated histologically at month 6. Results: No clinical complications were observed during follow-up period. In radiological evaluation, there was no statistically significant difference between groups regarding bone formation. In histological evaluation, the connective tissue was denser, and organized and better bone formation was observed in group 3 and 4 when compared with other groups. Conclusion: Although no significant radiological changes were present, porous polyethylene and resorbable mesh performed better histologically. They were effective and well tolerated for reconstruction of the isolated orbital floor defects.
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    The quantitative effect of botulinum toxin a over brow height
    (Lippincott Williams and Wilkins, 2013) Uygur, Halil Şafak; Bulam, Hakan; Yavuzer, Cahit Reha; Doctor; N/A; Doctor; Other; N/A; N/A; N/A; N/A; School of Medicine; N/A; Koç University Hospital; N/A; N/A; N/A; N/A; N/A
    Introduction: Botulinum toxin type A (BTX-A) is currently used in temporal brow lifting. Reducing the activity of the superolateral portion of orbicularis oculi muscle causes lateral brow elevation. The objective of this study was to determine the quantitative brow elevation after paralysis of the superolateral portion of orbicularis oculi muscle. Material and Methods: This study includes 10 female patients. Six units of BTX-A were injected into the superolateral portion of the orbicularis oculi in a serial manner into 3 points, below the lateral half of the brow at each side. Bilateral measurements were obtained by using calipers, immediately before and 2 weeks after the treatment. The medial canthus to the medial brow margin (AB), the lateral brow margin to the lateral canthus (CD), the medial brow margin to the lateral brow margin (BC), the brow apex to upper lid margin at the level of the lateral limbus (EF), the brow apex to the medial brow margin (EB), the brow apex to the lateral brow margin (EC), and upper eyelid margin to lower eyelid margin at the level of the pupil (GH), were measured. Results: There were no statistically significant differences found between pretreatment and posttreatment left and right measurements. There were statistically significant increases in CD, EF, and GH measurements, which are point out brow elevation. There were no statistically significant differences found in other measurements. Conclusions: Same doses of BTX-A application did not disrupt symmetry. Applications of 6U BTX-A to the superolateral portion of orbicularis oculi provide brow elevation and increased interpalbebral distance and upper eyelid distance. Our study has confirmed that BTX-A treatment of superolateral portion of the orbicularis oculi muscle produces quantitative temporal brow elevation.
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    Elevated plasma lipid levels in patients with epidermoid cysts
    (Medknow Publications & Media Pvt Ltd, 2016) Eryilmaz, Tolga; Cukurluoglu, Onur; N/A; Özmen, Selahattin; Uygur, Halil Şafak; Faculty Member; Doctor; School of Medicine; N/A; N/A; Koç University Hospital; 125951; N/A
    Objective: Epidermoid cysts are the most common type of skin cysts. We aimed to investigate whether there are any plasma lipid level differences in patients with epidermoid cysts. Material and Methods: Three-hundred forty-two patients (147 females and 195 males) were included. Patients' data (including plasma lipid levels) were retrospectively evaluated, and the results were compared with the average plasma lipid levels of the Turkish population. Results: A significant increase was found in plasma low-density lipoprotein (LDL)-cholesterol and triglyceride levels (p< 0.05) in patients with epidermoid cysts. Conclusion: Because the presence of elevated LDL-cholesterol and triglyceride levels may be accepted as a significant risk factor for coronary heart disease, we claim that the risk of coronary heart disease is increased in patients with epidermoid cysts. Further, high plasma lipid levels may be a result of sebaceous cysts or may be an effective mechanism of sebaceous cyst formation. Larger series of patients should be analyzed to evaluate this relation.
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    PublicationOpen Access
    Basal cell carcinoma in young patients
    (Türk Plastik Rekonstrüktif ve Estetik Cerrahi Derneği, 2017) Horoz, Uǧur; İnözü, Emre; Eryılmaz, Avni Tolga; Tellioǧlu, Ali Teoman; Uygur, Halil Şafak; Koç University Hospital
    Basal cell carcinoma (BCC) is the most common type of skin cancer and has a direct relationship with chronic sun exposure. Other risk factors include fair skin and eyes, freckling, family history, genetic disorders, immunosuppression, ionizing radiation, arsenic, and polyaromatic hydrocarbons. BCC usually progresses slowly. Lesions are usually seen over sun-exposed areas, which are most commonly on the face and neck. Local invasion may occur, but it rarely metastasizes. The incidence of BCC peaks in the seventh decade of life. BCC is an uncommon lesion during childhood, youth, and pregnancy. It has rarely been reported during childhood. BCC seen during childhood can be inherited with diseases such as xeroderma pigmentosum, albinism, Bazex syndrome, and basal cell nevus syndrome or after high-dose radiotherapy. In this study, we present the cases of a 14-year-old girl with BCC on the right popliteal region and a 23-year-old pregnant woman with BCC on the nasal tip. Both patients underwent total excision, and there were neither recurrence nor any complication during the follow-up.