Researcher:
Karakaya, Afak Durur

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Faculty Member

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Afak Durur

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Karakaya

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Karakaya, Afak Durur

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2020 - 20226

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    An unusual case of extrapulmonary tuberculosis in rheumatology consultation
    (Aves, 2022) Somay, Kayra; Eren, İlker; Kapmaz, Mahir; Çağlayan, Benan Niku; Karakaya, Afak Durur; Kanıtez, Nilüfer Alpay; Researcher; Faculty Member; Doctor; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; N/A; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; 168021; N/A; 230719; 269567; 239432
    N/A
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    Non-occlusive hepatic artery hypoperfusion syndrome and imaging findings: a systematic review
    (Springer, 2021) N/A; N/A; Karakaya, Afak Durur; Çil, Barbaros Erhan; Kanmaz, Turan; Oğuzkurt, Levent; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 269567; 169993; 275799; 13559
    Non-occlusive hepatic artery hypoperfusion syndrome (NHAHS), in other words, splenic steal, is a rare disorder that can arise following liver transplantation. After liver transplantation, its frequency has been defined as between 0.6 and 10.1%. The diversion of flow from hepatic to splenic arteries results in low perfused hepatic artery which causes elevated liver enzymes, hyperbilirubinemia, and graft dysfunction. This may result from a high resistance in the hepatic arteries, enlarged splenic arteries, a limited hepatic arterial flow due to high portal flow, or a discordance of the graft size and hepatic arterial flow. There may be a need for some prophylactic and/or posttransplant treatment procedures. We aimed to describe pre and post-treatment imaging findings of NHAHS.
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    Three consequent pediatric liver transplant deaths in the COVID-19 era
    (Avicenna Organ Transplant Center, 2020) N/A; N/A; Imam, Ashraf; Karataş, Cihan; Imam, Riham; Armutlu, Ayşe; Mecit, Nesimi; Karakaya, Afak Durur; Kalayoğlu, Münci; Kanmaz, Turan; Doctor; Doctor; Other; Teaching Faculty; Doctor; Faculty Member; Doctor; Faculty Member; N/A; N/A; N/A; School of Medicine; N/A; School of Medicine; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; N/A; N/A; Koç University Hospital; N/A; Koç University Hospital; N/A; N/A; N/A; N/A; 133567; N/A; 269567; N/A; 275799
    The effect of COVID-19 on the transplant recipients is not well-established. Many reports underestimate the effect of COVID-19 on the immunosuppressed population. Herein, we report on 3 pediatric liver transplant recipients who were transplanted at our center between February 11 and March 10, 2020-during the COVID-19 pandemic era. The 3 patients aged between 5 and 10 months, had a rapid and aggressive respiratory deterioration that necessitated mechanical ventilation and extracorporeal life support; and eventually died. The clinical and pathological pictures likely represent COVID-19 pneumonia. Chest x-rays showed progressive infiltrates. Lung autopsies showed diffuse alveolar damage in two cases. We concluded that COVID-19 is very likely to have catastrophic effects on transplant recipients.
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    PublicationOpen Access
    Three consequent pediatric liver transplant deaths in the COVID-19 era
    (Avicenna Organ Transplant Institute, 2020) Imam, Ashraf; Karataş, Cihan; Armutlu, Ayşe; Karakaya, Afak Durur; Kalayoğlu, Münci; Kanmaz, Turan; Teaching Faculty; Faculty Member; Faculty Member; Koç University Hospital
    The effect of COVID-19 on the transplant recipients is not well-established. Many reports underestimate the effect of COVID-19 on the immunosuppressed population. Herein, we report on 3 pediatric liver transplant recipients who were transplanted at our center between February 11 and March 10, 2020-during the COVID-19 pandemic era. The 3 patients aged between 5 and 10 months, had a rapid and aggressive respiratory deterioration that necessitated mechanical ventilation and extracorporeal life support; and eventually died. The clinical and pathological pictures likely represent COVID-19 pneumonia. Chest x-rays showed progressive infiltrates. Lung autopsies showed diffuse alveolar damage in two cases. We concluded that COVID-19 is very likely to have catastrophic effects on transplant recipients.
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    PublicationOpen Access
    Anatomical variations of the hepatic artery: a closer view of rare unclassified variants
    (Via Medica Journals, 2021) Karataş, Cihan; Mecit, Nesimi; Karakaya, Afak Durur; Yıldırımoğlu, Turan; Kalayoğlu, Münci; Kanmaz, Turan; Faculty Member; Faculty Member; Koç University Hospital
    Background: defining the hepatic artery anatomy is of great importance for both surgeons and radiologists. Michel classification was designed to classify hepatic artery variations. Nevertheless, there are variations that do not fit into this classification. In this study, we aim to define the incidence of all variations in a healthy liver donor by reviewing their CT scan with special emphasis on variations that do not fit in any of the Michel classes. Materials and methods: a retrospective analysis of CT scan of donors and potential liver donors who were evaluated by triphasic CT scan. The CT scans were reviewed independently by a radiologist and two transplant surgeons. Cases that did not fit in any of the Michel classes were classified as class 0. Results: out of 241 donors, 210 were classified within the Michel classification, of which 60.9 % were class I and 9.1% class II. Thirty-one donors (12.9%) classified as class 0. Of which, nine, three, two and three had replaced right hepatic artery from pancreaticoduodenal artery, gastroduodenal artery, aorta and celiac artery, respectively. Two and 6 donors had accessory right hepatic artery from pancreaticoduodenal artery and gastroduodenal artery respectively. Segment 4 artery originated from left and right hepatic artery in 56.8% and 31.9%, respectively. Conclusions: a great caution should be taken when evaluating the hepatic artery anatomy, clinicians should anticipate and be familiar with the rare unclassified variations of the hepatic artery.
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    PublicationOpen Access
    As a rare reason of alveolar consolidation, negative pressure pulmonary edema: case report
    (Logos Tıp Yayıncılığı, 2020) Karakaya, Muhammet Ahmet; Karakaya, Afak Durur; Faculty Member; School of Medicine
    In this paper we describe two cases with negative pressure pulmonary edema (NPPE). Excessive negative airway pressures against an obstructed airway has been reported to cause fluid filtration into alveoli and lung edema. The patients are generally young adults without any medical prob-lems. The condition involves central interstitial area of both lungs and is treated by nonnvasive mechanical ventilation and corticosteroids. / Bu yazıda negatif basınçlı akciğer ödemi (NPPE) olan iki olgu tanımlanmıştır. Tıkalı bir hava yoluna karşı, aşırı negatif hava yolu basıncının alveollerde ve akciğerde ödeme neden olduğu bildirilmiştir. Hastalar genellikle herhangi bir tıbbi problemi olmayan genç yetişkinlerdir. Bu durum, her iki akciğerin santral interstisyel bölgesini içerir ve noninvaziv mekanik ventilasyon ve kortikosteroidlerle tedavi edilir.