Researcher:
Yurtsever, Zeynep

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Undergraduate Student

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Zeynep

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Yurtsever

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Yurtsever, Zeynep

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Now showing 1 - 2 of 2
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    Publication
    Competitive hydrogen bonding in aspirin-aspirin and aspirin-leucine interactions
    (Scientific Technical Research Council Turkey-Tubitak, 2012) Department of Chemistry; Department of Chemical and Biological Engineering; Department of Chemistry; Department of Chemical and Biological Engineering; Department of Chemistry; Yurtsever, Zeynep; Erman, Burak; Yurtsever, İsmail Ersin; Undergraduate Student; Faculty Member; Faculty Member; College of Sciences; College of Engineering; College of Sciences; N/A; 179997; 7129
    Aspirin-aspirin and aspirin-leucine interactions are studied by the density functional theory (DFT) and high level ab initio calculations with second order Moller-Plesset perturbation theory (MP2). The rotational isomers of aspirin are identified by their relative stability both in gaseous phase and in water using the polarizable continuum method (PCM). Local minima of aspirin monomers in water are found to be all highly populated compared to the gas phase behavior. Homodimers of aspirin form hydrogen bonds with bond energies of 10 kcal/mol. Weak hydrogen bonds utilizing phenyl and methyl groups are also found. The interaction between aspirin and leucine is stronger with relatively short bond lengths compared to homodimeric aspirin interactions. The potential energy surface has several minima with comparable stability. This study shows the significance of diverse bonding schemes, which are important for understanding complete interaction mechanisms of aspirin.
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    Publication
    Production and comprehension of co-speech gestures in Parkinson's disease
    (2021) N/A; N/A; N/A; N/A; N/A; Department of Psychology; Department of Psychology; Yurtsever, Zeynep; Çakmak, Özgür Öztop; Eser, Hale Yapıcı; Ertan, Fatoş Sibel; Lira, Özlem Ece Demir; Göksun, Tilbe; N/A; Faculty Member; Faculty Member; Faculty Member; N/A; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; N/A; College of Social Sciences and Humanities; N/A; 299358; 134359; 112829; N/A; 47278
    This study examined how impairments in sensorimotor abilities of individuals with Parkinson's Disease (PD) can be related to the use and understanding of co-speech hand gestures involving literal and figurative actions. We tested individuals with PD (n = 18, 12 males, Mage = 56.5, SDage = 8.16, PD duration since onset: M = 5.36 years, SD = 3.51, Hoehn and Yahr Scale:MH&Y = 2.09, SDH&Y = 0.50) and age- and education-matched neurotypical controls (n = 18, 14 males, Mage = 56.61, SDage = 8.88) with two experimental tasks. In the gesture production task, participants retold the narratives presented to them in a written format. In the gesture comprehension task, participants were asked to match a gesture with a novel verb in literal and figurative sentence contexts. Results showed that patients with PD gestured significantly less than the neurotypical controls. No group differences were found for the type of gesture use. Individuals with PD performed worse than controls on matching gestures with novel verbs, particularly for figurative meanings. Individuals' severity in the disease negatively correlated with their performance for these figurative novel verb-gesture matches. The performances in the two tasks did not correlate. These findings suggest that problems in sensorimotor abilities resulting from PD can influence overall gesture production and gesture comprehension, providing further evidence on the relations between PD and the impaired use of multimodal language.