Researcher:
Böge, Medine

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Faculty Member

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Medine

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Böge

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Böge, Medine

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2017 - 20206

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Researcher Of Publications: search.filters.isAuthorOfPublication.932d3978-10a9-41af-9d10-d4fbcfa9a854

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Now showing 1 - 6 of 6
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    PublicationOpen Access
    Response to "Clarification needed for case presented in 'the excision of the buccal fat pad for cheek refinement: volumetric considerations'"
    (Oxford University Press (OUP), 2019) N/A; N/A; Sezgin, Billur; Tatar, Sedat; Böge, Medine; Özmen, Selahattin; Yavuzer, Cahit Reha; Faculty Member; Faculty Member; School of Medicine
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    PublicationOpen Access
    Stercoral colitis: diagnostic value of CT findings
    (Aves, 2017) Ünal, Emre; Onur, Mehmet Ruhi; Balcı, Sinan; Görmez, Ayşegül; Akpınar, Erhan; N/A; Böge, Medine; School of Medicine
    PURPOSE: We aimed to evaluate the CT findings of stercoral colitis (SC). METHOD: Forty-one patients diagnosed with SC between February 2006 and April 2015 were retrospectively reviewed. RESULTS: Rectosigmoid colon was the most frequently involved segment (100%, n= 41). CT findings can be summarized as follows: dilatation >6 cm and wall thickening > 3 mm of the affected colon segment (100%, n= 41), pericolonic fat stranding (100%, n= 41), mucosal discontinuity (14.6 %, n= 6), presence of free air (14.6%, n= 6), free fluid (9.7%, n= 4), and pericolonic abscess (2.4%, n= 1). The sign most related with mortality was the length of the affected colon segment > 40 cm. CONCLUSION CT has an important role in SC, since life-threatening complications can be easily revealed by this imaging modality. Increased length of involved colon segment (> 40 cm) is more likely to be associated with mortality.
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    PublicationOpen Access
    Multiparametric MRI of rectal cancer-repeatability of quantitative data: a feasibility study
    (Aves, 2020) Gürses, Bengi; Altınmakas, Emre; Böge, Medine; Aygün, Murat Serhat; Bayram, Onur; Balık, Emre; Faculty Member; Other; Faculty Member; School of Medicine; N/A; N/A; N/A; N/A; N/A; 18758
    Purpose: in this study, we aimed to analyze the repeatability of quantitative multiparametric rectal magnetic resonance imaging (MRI) parameters with different measurement techniques. Methods: all examinations were performed with 3 T MRI system. In addition to routine sequences for rectal cancer imaging protocol, small field-of-view diffusion-weighted imaging and perfusion sequences were acquired in each patient. Apparent diffusion coefficient (ADC) was used for diffusion analysis and k(trans) was used for perfusion analysis. Three different methods were used in measurement of these parameters; measurements were performed twice by one radiologist for intraobserver and separately by three radiologists for interobserver variability analysis. ADC was measured by the lowest value, the value at maximum wall thickness, and freehand techniques. K-trans was measured at the slice with maximum wall thickness, by freehand drawn region of interest (ROI), and at the dark red spot with maximum value. Results: a total of 30 patients with biopsy-proven rectal adenocarcinoma were included in the study. The mean values of the parameters measured by the first radiologist on the first and second measurements were as follows: mean lowest ADC, 721.31 +/- 147.18 mm(2)/s and 718.96 +/- 135.71 mm(2)/s; mean ADC value on the slice with maximum wall thickness, 829.90 +/- 144.24 mm(2)/s and 829.48 +/- 149.23 mm(2)/s; mean ADC value measured by freehand ROI on the slice with maximum wall thickness, 846.56 +/- 136.31 mm(2)/s and 848.23 +/- 144.15 mm(2)/s; mean k(trans) value on the slice with maximum wall thickness, 0.219 +/- 0.080 and 0.214 +/- 0.074; mean k(trans) by freehand ROI technique (including as much tumoral tissue as possible), 0.208 +/- 0.074 and 0.207 +/- 0.069; mean k(trans) measured from the dark red foci, 0.308 +/- 0.109 and 0.311 +/- 0.105. Intraobserver agreement was very good among diffusion and perfusion parameters obtained with all three measurement techniques. Interobserver agreement was very good, except for one of the measurement techniques. As far as interobserver variability is considered, only ADC value measured on the slice with maximum wall thickness differed significantly. Conclusion: multiparametric MRI of rectum, using ADC as the diffusion and k(trans) as the perfusion parameter is a repeatable technique. This technique may potentially be used in prediction and evaluation of neoadjuvant treatment response. New studies with larger patient groups are needed to validate the role of multiparametric MRI.
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    PublicationOpen Access
    Multiparametric MRI in rectal cancer
    (Aves, 2019) N/A; N/A; Gürses, Bengi; Böge, Medine; Altınmakas, Emre; Balık, Emre; Faculty Member; Other; Faculty Member; School of Medicine; N/A; N/A; N/A; 18758
    MRI has a pivotal role in both pretreatment staging and posttreatment evaluation of rectal cancer. The accuracy of MRI in pretreatment staging is higher compared with posttreatment evaluation. This occurs due to similar signal intensities of tumoral and posttreatment fibrotic, necrotic, and inflamed tissue. This limitation occurs with conventional MRI of the rectum with morphologic sequences. There is a need towards increasing the accuracy of MRI, especially for posttreatment evaluation. The term multiparametric MRI implies addition of functional sequences, namely, diffusion and perfusion to the routine protocol. This review summarizes the technique, potential implications and previously published studies about multiparametric MRI of rectal cancer.
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    PublicationOpen Access
    Intraductal papillary mucinous neoplasm of the pancreas associated with neuroendocrine tumor: a case report
    (Elsevier, 2017) Vural, M.; Yilmaz, S.; Goksel, S.; N/A; N/A; Gürses, Bengi; Böge, Medine; Bilge, Orhan; Faculty Member; Faculty Member; School of Medicine; N/A; N/A; 176833
    Introduction: Intraductal papillary mucinous neoplasm is an uncommon cystic tumor of pancreas that can be associated with ductal adenocarcinoma. Coexistence of pancreatic IPMN and neuroendocrine tumor is very rare. Here, we report the imaging features of mixed type intraductal papillary mucinous neoplasia of the pancreas with high grade dysplasia together with neuroendocrine carcinoma and perform review of the literature. Presentation: A 68-year old patient has been evaluated for possible IPMN that was suspected during ultrasound. MRI revealed main and side branch duct dilatations. At the head, a contrast enhancing nodular lesion was identified. Due to the presence of high risk stigmata according to guidelines, surgery was performed. Histopathological examination revealed an unusual association, including mixed type IPMN and neuroendocrine carcinoma. Discussion: The concomitant occurrence of pancreatic IPMN and neuroendocrine tumor has been reported in case studies and brief reviews. Yet, the imaging findings and underlying molecular mechanisms of this entity has not been fully understood. In addition to this unusual association, pancreatic intraepithelial neoplasia was also detected in the present case. Although majority of neuroendocrine tumor associated ipmns were reported to be having low grade dysplasia, our patient had high grade dysplasia. Further studies and reviews with larger groups are needed to establish imaging features and underlying molecular mechanisms of this rare association. Conclusion: Although the major concern during work-up of IPMN is presence of associated pancreatic ductal adenocarcinoma, the possibility of neuroendocrine tumor, in the presence of a hypervascular solid foci on imaging studies should be kept in mind.
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    PublicationOpen Access
    The excision of the buccal fat pad for cheek refinement: volumetric considerations
    (Oxford University Press (OUP), 2019) N/A; Sezgin, Billur; Tatar, Sedat; Böge, Medine; Özmen, Selahattin; Yavuzer, Cahit Reha; Faculty Member; Faculty Member; School of Medicine
    Background: although the excision of the buccal fat pad has become very popular for achieving a slimmer midface, not all patients are good candidates for this procedure. Unfortunately, studies that provide guidelines by emphasizing volumetric and technical details are limited. Objectives: the study compared preoperative and postoperative volumetric data to identify the amount of tissue that can safely be removed and important technical concepts involved in lower cheek contouring with buccal fat pad excision. Methods: patients complaining of cheek fullness were evaluated to determine if they were good candidates for the procedure. Eligible patients were screened with transbuccal ultrasound to determine tissue volumes and anatomical details. Intraoperative and postoperative, 6th-month volume measurements were undertaken and residual tissues and vascular pedicles reevaluated. Results: ultrasound imaging showed that the mean preoperative volume of the fat pads was 11.67 ± 1.44 mL, and the mean postoperative volume was 8.58 ± 1.07 mL. The mean volume of the excised tissues was 2.74 ± 0.69 mL. Postoperative buccal fat pad volume values correlated with the reported average in the literature for the same age group. Conclusions: Buccal fat pad removal is an effective technique for refining the facial silhouette that should be reserved for patients with increased buccal fat pad volume. Removal of only the excessive portion of the fat pad is important because this structure provides significant volume in the midface that can be difficult to restore once aging affects the surrounding soft and bony tissue.