Researcher:
Kordan, Yakup

Profile Picture
ORCID

Job Title

Faculty Member

First Name

Yakup

Last Name

Kordan

Name

Name Variants

Kordan, Yakup

Email Address

Birth Date

Filters

2017 - 201972020 - 202316

Advanced Search

Filter by

Settings

Researcher Of Publications: search.filters.isAuthorOfPublication.99f8f813-b211-480c-a1d1-c7ff5e6d35ab

Search Results

Now showing 1 - 10 of 24
  • Placeholder
    PublicationMetadata only
    Fluorescence-guided extended pelvic lymphadenectomy during robotic radical prostatectomy
    (Springernature) N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Özkan, Arif; Köseoğlu, Ersin; Canda, Abdullah Erdem; Çil, Barbaros Erhan; Aykanat, İbrahim Can; Sarıkaya, Ahmet Furkan; Tarım, Kayhan; Armutlu, Ayşe; Kulaç, İbrahim; Barçın, Erinç; Falay, Fikri Okan; Kordan, Yakup; Baydar, Dilek Ertoy; Balbay, Mevlana Derya; Esen, Tarık; Doctor; Faculty Member; Faculty Member; Faculty Member; Doctor; Researcher; Researcher; Teaching Faculty; Faculty Member; Undergraduate Student; Teaching Faculty; Faculty Member; Faculty Member; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 350876; 116202; 169993; N/A; 327615; 327605; 133567; 170305; N/A; 246484; 157552; 8025; 153320; 50536
    We evaluated and described the impact of prostatic indocyanine green (ICG) injection on extended pelvic lymph node (LN) dissection (ePLND) in robotic-assisted radical prostatectomy (RARP). Between January 2019 and December 2021, we included consecutive 50 PCa patients who underwent ePLND during RARP with (n = 25) or without (n = 25) prostatic ICG injection. ICG injection was performed during abdominal port placement and robot docking. Pelvic LNs reflecting green color were initially excised and then the template was completed. The outcomes of two groups were compared. Overall, nine (36%) and five (20%) of the patients had metastatic LN involvement in the ICG and non-ICG groups, respectively. Of the 509 dissected LNs in the ICG group, 122 (23.9%) were fluorescence active. 20 LNs (3.9%) were metastatic in this group, 9 (45%) of which were ICG+. 408 LNs were resected on the non-ICG group with 8(1.9%) being metastatic. Eight (88.9%) of nine pN+ patients were florescent positive in the ICG group. Out of six patients with pN+ disease, Ga68 PSMA-PET/CT detected positive LNs preoperatively. In addition to preoperative Ga68 PSMA-PET/CT investigation, ICG-guided ePLND might increase identification and removal of metastatic LNs duirng RARP. Improvements in staging and oncologic outcomes may also be seen in intermediate- and high-risk patients.
  • Placeholder
    PublicationMetadata only
    Minimally invasive management of zinner's syndrome with same-session robot-assisted seminal vesiculectomy and ipsilateral nephroureterectomy using a single geometry of trocars
    (Mary Ann Liebert, Inc., 2018) Sağ, Alan Alper; Kılıç, Mert; N/A; Kiremit, Murat Can; Acar, Ömer; Köseoğlu, Ersin; Kordan, Yakup; Balbay, Mevlana Derya; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; Koç University Hospital; N/A; N/A; 222920; 237530; 350876; 350876; 153320
    Background: seminal vesicle cyst is an extremely rare condition, which is frequently congenital and associated with Zinner's syndrome. This syndrome represents a constellation of seminal vesicle cyst, ipsilateral or contralateral renal agenesis or renal dysplasia, ureteral ectopia, and ejaculatory duct obstruction. We report a young symptomatic patient undergoing robot-assisted laparoscopic excision of a huge seminal vesicle cyst during which an atrophic ipsilateral kidney was discovered incidentally and managed by nephroureterectomy in the same session without changing trocar positions. Case Presentation: a 23-year-old male patient presented with a 2-year history of lower urinary tract symptoms, perineal pain, and recurrent urinary tract infections. Ultrasonography revealed the absence of left kidney and a fluid-filled cystic lesion located behind the bladder on the left side, which was consistent with cystic dilatation of the left seminal vesicle. MRI confirmed the diagnosis of a huge cystic structure originating from the left seminal vesicle and identified the presence of a rudimentary left ureter without an associated renal unit. Cystoscopy revealed bulging of the bladder neck at 6 o'clock position and the ureteral orifices at normal positions and configurations. Based on these findings, the clinical diagnosis was established as Zinner's syndrome. The present case was performed by Da Vinci Si robotic platform using the 5-trocar technique. Conclusion: robot-assisted laparoscopic excision is a safe and feasible option to treat large seminal vesicle cysts, which may be a component of Zinner's syndrome. Simultaneous upper urinary tract interventions, such as nephroureterectomy, can be employed by redocking the robot and repositioning the patient, using the same layout of robotic trocars.
  • Placeholder
    PublicationMetadata only
    Is robotic transperitoneal partial nephrectomy safe in the management of cystic renal cell masses? Outcomes of an ERUS multicenter study including 216 patients
    (ELSEVIER, 2021) Mottrie, A.; Challacombe, B.; Montorsi, F.; Ener, K.; Ploumidis, A.; Larcher, A.; Decaestecker, K.; De Luyk, N.; Buffi, N.; Uleri, A.; Gallina, A.; De Naeyer, G.; Guazzoni, G.; Fernando, A.; Briganti, A.; Cestari, A.; Catterwell, R.; Van Praet, C.; Capitanio, U.; Pappas, A.; N/A; Canda, Abdullah Erdem; Kordan, Yakup; Esen, Tarık; Balbay, Mevlana Derya; Faculty Member; Faculty Member; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; 116202; 157552; 50536; 153320
    N/A
  • Placeholder
    PublicationMetadata only
    The impact of visible tumor (PI-RADS >= 3) on upgrading and adverse pathology at radical prostatectomy in low risk prostate cancer patients: a biopsy core based analysis
    (Cig Media Group, Lp, 2022) Kilic, Mert; Saglican, Yesim; Tugcu, Volkan; Bakir, Baris; N/A; Özkan, Arif; Köseoğlu, Ersin; Balbay, Mevlana Derya; Canda, Abdullah Erdem; Kordan, Yakup; Kiremit, Murat Can; Esen, Tarık; Baydar, Dilek Ertoy; Çil, Barbaros Erhan; Doctor; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Faculty Member; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 289255; 350876; 153320; 116202; 157552; 222920; 50536; 8025; 169993
    Deciding on the management of prostate cancer (PCa), especially GG1 PCa, is quite difficult. The most important thing that will help us in making active surveillance or definitive treatment decision is whether the tumor is a clinically significant tumor. To understand this, we discussed in this article that multiparametric MR, PI-RADS scoring and targeted biopsy can be used. Background
  • Placeholder
    PublicationMetadata only
    Postchemotherapy robotic retroperitoneal lymph node dissection for non-seminomatous germ cell tumors in the lateral decubitus position: oncological and functional outcomes
    (Springer, 2023) Kilic, Mert; N/A; Kordan, Yakup; Köseoğlu, Ersin; Esen, Barış; Özkan, Arif; Kiremit, Murat Can; Esen, Tarık; Faculty Member; Faculty Member; Teaching Faculty; Doctor; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; N/A; School of Medicine; School of Medicine; N/A; N/A; N/A; Koç University Hospital; N/A; N/A; 157552; 350876; 199167; 222920; 50536
    Purpose Retroperitoneal lymph node dissection (RPLND) is recommended for residual masses following chemotherapy for non-seminomatous germ cell tumors (NSGCT). Recently, aberrant recurrence patterns were reported in patients who underwent robotic RPLND. We aimed to evaluate perioperative safety in addition to functional and early oncological outcomes of postchemotherapy robotic RPLND (pcR-RPLND) for NSGCT.Methods A total of 25 patients with NSGCT who underwent a pcR-RPLND between January 2011 and June 2022 were evaluated retrospectively. Descriptive statistics were provided for demographics, clinical characteristics, intraoperative and postoperative parameters. Functional and oncological outcomes were recorded.Results The median patient age was 28.9 years (IQR 21.5-32.4). The median retroperitoneal tumor size was 2.6 cm (IQR 1.5-3.5). Intraoperative complications occurred in only one case and the open conversion rate was 12%. There were seven cases with postoperative complications (Clavien grade II: 5 and IIIa: 2). Patients were followed for a median of 33.2 months (IQR 14.8-43.0). Antegrade ejaculation was preserved in 85.7% of the patients. Two patients (8%) relapsed and both had out-of-field recurrences at unusual sites (perinephric fat and omentum). of those, one patient died (4%) of testicular cancer.Conclusion pcR-RPLND is a feasible and technically reproducible procedure with favorable perioperative morbidity, low rate of complications, and acceptable postoperative ejaculatory function. Although the recurrence rate was low (8%), recurrences were observed at unusual sites. Further studies are required to investigate any association between the robotic approach and aberrant recurrence patterns.
  • Placeholder
    PublicationMetadata only
    Implanting a robot-assisted kidney transplant program for transplant surgeons with no robotic surgery background
    (Lippincott Williams and Wilkins, 2022) N/A; N/A; Koçak, Burak; Çelik, Neslihan; Arpalı, Emre; Akyollu, Başak; Kılıçer, Beşir; Canda, Abdullah Erdem; Kordan, Yakup; Faculty Member; PhD Student; Doctor; Doctor; Other; Faculty Member; Faculty Member; School of Medicine; Graduate School of Health Sciences; N/A; N/A; N/A; School of Medicine; School of Medicine; N/A; N/A; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; 220671; N/A; N/A; N/A; N/A; 116202; 157552
    N/A
  • Placeholder
    PublicationMetadata only
    [Ga-68]Ga-PSMA-11 and [F-18]FDG uptake of venous tumor thrombus in inferior vena cava and left common iliac vein from prostate cancer on positron emission tomography
    (Springer, 2023) Kabaoğlu, Zeynep Ünal; N/A; Seymen, Hülya; Esen, Barış; Kulaç, İbrahim; Aksoy, Murat; Demirkol, Mehmet Onur; Kordan, Yakup; Teaching Faculty; Teaching Faculty; Faculty Member; Other; Faculty Member; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 350778; 199167; 170305; N/A; 196946; 157552
    N/A
  • Placeholder
    PublicationMetadata only
    Prostate-specific membrane antigen positron emission tomography as a biomarker to assess treatment response in patients with advanced prostate cancer
    (Elsevier, 2023) Herrmann, Ken; Bavbek, Sevil; Esen, Tarık; Kordan, Yakup; Esen, Barış; Tilki, Derya; Faculty Member; Faculty Member; Teaching Faculty; Other; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 50536; 157552; 199167; N/A
    Context: Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) has superior accuracy for detection of metastatic lesions in patients with prostate cancer (PC). Although PSMA PET has a prominent role in primary and secondary imaging of PC, data on its role in assessing treatment response in advanced PC are limited. Objective: To review current data in the literature regarding the impact of antiandrogen therapy on PSMA expression of metastatic sites and the role of serial (baseline and at least 1 follow-up scan) PSMA PET to assess treatment response in patients with metastatic PC. Evidence acquisition: A comprehensive literature search in the PubMed database was performed using the terms “PSMA expression prostate”, “PSMA regulation”, “PSMA PET response assessment”, and “serial PSMA PET”. Evidence synthesis: Serial PSMA PET studies (baseline and at least 1 follow-up scan) provide valuable data regarding PSMA expression changes after systemic treatment in patients with metastatic PC. PSMA PET–detected flare and upregulation of PSMA expression following hormonal intervention seem to be early events resolving after 3 mo of treatment. PSMA PET imaging is essential in selecting patients for 177Lu-PSMA radioligand therapy (RLT). Growing evidence favors its use in assessing treatment responses after RLT. Preliminary evidence indicates the value of PSMA PET for assessment of the treatment response in patients receiving systemic treatment other than RLT for metastatic PC. Conclusions: PSMA flare following antiandrogen therapy seems to be an early event and thus PET scans should be performed no earlier than 3 mo after the start of treatment. PSMA PET has a promising role in tailoring treatment according to the specific needs of individual patients and assessing responses following systemic treatment in patients with advanced PC. Patient summary: This review describes how a sensitive imaging method can be used to assess the tumor response to treatment for metastatic prostate cancer.
  • Placeholder
    PublicationMetadata only
    RNA-based markers in biopsy cores with atypical small acinar proliferation: predictive effect of T2E fusion positivity and MMP-2 upregulation for a subsequent prostate cancer diagnosis
    (Wiley, 2019) Eryilmaz, I. Ezgi; Vuruskan, Berna Aytac; Kaygisiz, Onur; Egeli, Unal; Tunca, Berrin; Cecener, Gulsah; N/A; Kordan, Yakup; Faculty Member; School of Medicine; 157552
    Background Atypical small acinar proliferation (ASAP) is a precursor lesion of prostate cancer (PC), and PC develops from this suspicious focus or an unsampled malignant gland nearby. However, PC-related molecular alterations that could guide the timing of repeat biopsies and help monitor PC risk in ASAP-diagnosed patients have not been investigated. The purpose of this study was to first investigate the expression of seven different PC-related RNAs that included serine 2 (TMPRSS2): erythroblastosis virus E26 oncogene homolog (ERG) gene (TMPRSS2-ERG, T2E) fusion, alpha-methylacyl-CoA racemase (AMACR), kallikrein related peptidase 3 (KLK3), androgen receptor (AR), prostate cancer specific antigen 3 (PCA3), and matrix metalloproteinases (MMP)-2 and 9. Methods PC-related RNAs were evaluated using a real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) system in pathologically ASAP-diagnosed prostate biopsy cores from 55 patients presenting with a normal digital rectal examination and a PSA level of 4-10 ng/mL. Results We detected that positive T2E fusion status (P = 0.013) and the expression of AMACR (P = 0.016), AR (P = 0.016) and MMP-2 (P = 0.013) were independently and significantly associated with PC risk in ASAP patients. There were also several statistically significant correlations between expression levels. Additionally, we demonstrated that T2E fusion positive ASAP patients with higher MMP-2 expression were more likely to be diagnosed with PC at a subsequent biopsy during the follow-up period (P = 0.003). Conclusions Although, more clinical validations are needed for the stratification of PC risk in ASAP-diagnosed biopsy cores, our current results indicate that the coexistence of T2E fusion positivity with MMP-2 upregulation may help clinicians adjust their biopsy timetable and/or assessment of PC risk in ASAP-diagnosed patients with a PSA level of 4-10 ng/mL.
  • Placeholder
    PublicationMetadata only
    Robotic partial nephrectomies with selective/superselective clamping of renal artery branch by using indocyanine green (icg)
    (Elsevier, 2022) Kılıç, M; N/A; Kordan, Yakup; Köseoğlu, Ersin; Sarıkaya, Ahmet Furkan; Tarım, Kayhan; Kiremit, Murat Can; Canda, Abdullah Erdem; Balbay, Mevlana Derya; Esen, Tarık; Özkan, Arif; Faculty Member; Faculty Member; Researcher; Researcher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Doctor; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; Koç University Hospital; 157552; 350876; 327615; 327605; 222920; 116202; 153320; 50536; 289255
    N/A