Researcher: Tüfekçi, Tutku
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Publication Metadata only Role of emotion regulation and fear of compassion on depression and anxiety in patients with colorectal cancer(Kartal Eğitim ve Araştırma Hastanesi, 2022) Kılıç, Özge; Dikmen, Yasemin; N/A; Özata, İbrahim Halil; Yalçınay-İnan, Merve; Tüfekçi, Tutku; Ağcaoğlu, Orhan; Kuşçu, Kemal; Balık, Emre; Teaching Faculty; Doctor; Researcher; Faculty Member; Faculty Member; Faculty Member; School of Medicine; N/A; School of Medicine; School of Medicine; School of Medicine; N/A; Koç University Hospital; N/A; N/A; N/A; 177151; N/A; 327608; 175476; N/A; 18758INTRODUCTION: Maladaptive emotion regulation (ER) styles act as transdiagnostic mechanisms that underlie many psychiatric symptoms linked to cancer. ER and fear of compassion (FC) were studied in breast cancer, but their effects on psychiatric symptoms of colorectal cancer (CRC) patients are not studied. We aim to examine the role of ER and FC on depression and anxiety in Turkish CRC patients. METHODS: This observational, cross-sectional study recruited 38 patients with CRC who were being followed up by the general surgery department of a university hospital. Emotion Regulation Questionnaire, Fear of Compassion Scale, the Exercise of Self-care Agency Scale, Hospital Anxiety and Depression Scale, Distress Thermometer, Numeric Pain Intensity Scale, and Ostomy Adjustment Inventory were applied. Multiple regression analyses were performed to identify factors affecting depression and anxiety levels. RESULTS: Twenty-nine men and 9 women (median age=56.5, 28–69), most of whom were married and highly educated, were recruited. Expressive suppression (p=0.013) and pain (p=0.010) positively (Model, R2=0.42, p<0.001) and self-care agency (p=0.021) negatively influenced anxiety levels. Expressive suppression (p=0.017) and male gender (p=0.020) positively influenced depression levels (Model, R2=0.28, p=0.003). There was no association between cognitive reappraisal and levels of depression and anxiety. Among ostomates (n=17), 11 patients had low and 6 patients had medium adaptation to an active ostomy. No patient exhibited high adjustment to an ostomy. DISCUSSION AND CONCLUSION: Findings indicate that in CRC patients, expressive suppression affects levels of anxiety and depression while cognitive reappraisal does not. FC was not found to be related to anxiety and depression. Physicians should carefully observe the patients’ and the caregivers’ ER strategies and the dynamic and interactive psychological states to understand which patients need psychological and psychiatric interventions. We suggest future studies explore the interventions that target expressive suppression patterns to prevent anxiety and depression in CRC patients. / GİRİŞ ve AMAÇ: Uyumsal olmayan emosyon düzenleme biçimleri, kanserle ilişkili psikiyatrik belirtilerin altında yatan tanılar üstü mekanizmalar olarak rol oynar. Emosyon düzenleme ve şefkat korkusu meme kanseri hastalarında incelenmiştir ancak kolorektal kanser hastalarında psikiyatrik belirtiler üzerine etkileri araştırılmamıştır. Emosyon düzenleme ve şefkat korkusunun depresyon ve anksiyete üzerindeki rolünü Türk kolorektal kanser hastalarında incelemeyi amaçladık. YÖNTEM ve GEREÇLER: Bu gözlemsel, kesitsel çalışmaya, bir üniversite hastanesinin genel cerrahi bölümü tarafından takip edilen 38 kolorektal kanser hastası alındı. Emosyon Düzenleme Ölçeği, Şefkat Korkusu Ölçeği, Özbakım Gücü Ölçeği, Hastane Anksiyete ve Depresyon Ölçeği, Distres Termometresi, Sayısal Ağrı Derecelendirme Ölçeği, ve Stomaya Uyum Envanteri uygulandı. Depresyon ve anksiyeteyi etkileyen faktörleri belirlemek için çoklu regresyon analizleri yapıldı. BULGULAR: Çalışmaya çoğu evli ve yüksek eğitimli (medyan yaş= 56.5, 28–69) olan 29 erkek, 9 kadın alındı. Anksiyete düzeyleri üzerine dışavurumu bastırma (p=0.013) ve ağrının (p=0.010) etkisi pozitif, özbakım gücünün (p=0.02) etkisi negatifti (Model, R2=0.42, p<0.001). Depresyon düzeyleri üzerineyse dışavurumu bastırma (p=0.017) ve erkek cinsiyet (p=0.020) pozitif yönde etki etmekteydi. (Model, R2=0.28, p=0.003). Bilişsel yeniden değerlendirme ile depresyon ve ve anksiyete arasında ilişki saptanmadı. Stomaya uyum aktif stomalı hastaların (n=17) 11’inde düşük, altısında ortaydı. Stomaya yüksek uyum gözlenmedi. TARTIŞMA ve SONUÇ: Sonuçlar, kolorektal kanser hastalarında dışavurumu bastırmanın anksiyete ve depresyon düzeylerini etkilediğini, bilişsel yeniden değerlendirmenin ise bu düzeyleri etkilemediğini göstermiştir. Şefkat korkusu anksiyete ve depresyonla ilişkili bulunmamıştır. Hekimler, hangi hastaların psikolojik veya psikiyatrik müdahaleye ihtiyaç duyduğunu anlamak için hasta ve bakımverenin emosyon düzenleme biçimlerini ve dinamik ve etkileşimli psikolojik durumlarını dikkatle gözlemelidir. Gelecek çalışmaların kolorektal kanser hastalarında anksiyete ve depresyonu önlemek için dışavurumu bastırma paternini hedef alan müdahaleleri araştırmasını öneririz.Publication Metadata only Single-incision robotic adrenalectomy (SIRA): the future of adrenal surgery?(Ame Publishing Company, 2020) Ağcaoğlu, Orhan; Tezelman, Tevfik Serdar; Karahan, Salih Nafiz; Tüfekçi, Tutku; Faculty Member; Faculty Member; Researcher; Researcher; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 175476; 114860; 337050; 327608In compliance with the trend toward less invasive techniques, single incision robotic surgeries have become more common and they have been increasingly used for several surgeries including adrenalectomy. Single incision robotic adrenalectomy (SIRA) aims to combine the merits of robotic surgery with previously defined single incision laparoscopic techniques. It has been shown to be safe and feasible, however, there are only few studies on this new technique. Due to scant data on SIRA in the current literature, it remains to be a current challenge in adrenal surgery. In this review, our goal is to present current literature on SIRA and discuss the data regarding perioperative outcomes, patient selection, learning curve, and its limitations.Publication Open Access Effects of the largest metastatic lymph node size on the outcomes of patients who underwent pancreaticoduodenectomy for pancreatic ductal adenocarcinoma(Kare Yayıncılık, 2022) Bilgiç, Çağrı; Bozkurt, Emre; Tüfekçi, Tutku; Sucu, Serkan; Özoran, Emre; Özata, İbrahim Halil; Kaya, Mesut; Tellioğlu, Gürkan; Bilge, Orhan; Researcher; Researcher; Teaching Faculty; Teaching Faculty; Faculty Member; Faculty Member; School of Medicine; Koç University Hospital; N/A; N/A; N/A; 307296; N/A; N/A; N/A; 176833Objectives: prognostic importance of metastatic lymph nodes in pancreatic cancer is always garnered attention due to dismal prognosis, with some quantitative factors drawing attention for significantly predicting outcomes. Size is one of the easy approach morphological characteristics of the lymph node, and data for effect of largest metastatic lymph node (LMLN) size on survival outcomes are lacking in pancreatic cancer. We aim to evaluate the effect of LMLN size on the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC). Methods: this retrospective study evaluates the effect of LMLN size on survival outcomes by grouping the patients who were surgically treated for PDAC, according to their lymph node stage and calculated cutoff value for LMLN size, between February 2015 and May 2020. Results: in the study cohort of 131 patients, the mean age was 63.9 +/- 10.8 years and 77 patients were female. Ninety-nine of the pa-tients had pN1, 32 had pN2 stage disease. The optimal cutoff point of LMLN size for predicting the prognosis was calculated as 7.5 mm (sensitivity = 81% and specificity = 81%). 34 (34.3%) of pN1 and 7 (21.9%) of pN2-staged patients had lymph node smaller than 7.5 mm. Three-year survival was significantly longer for patients whose LMLN size was <7.5 mm (56.2-18.2%, p<0.001). Whereas, the patients with LMLN size <7.5 mm had statistically significant longer median survival rate in the subgroup of patients with pN1 lymph node stage, no significant difference in median survival rates was observed between subgroups of pN2 patients (p=0.237). Conclusion: the present study demonstrated that the LMLN size was one of the potential predictors of survival in patients with PDAC.Publication Open Access Single-incision robotic adrenalectomy (SIRA): the future of adrenal surgery?(AME Publishing Company, 2020) Ağcaoğlu, Orhan; Karahan, Salih Nafiz; Tüfekçi, Tutku; Tezelman, Tevfik Serdar; Faculty Member; Researcher; Researcher; School of Medicine; 175476; N/A; N/A; N/AIn compliance with the trend toward less invasive techniques, single incision robotic surgeries have become more common and they have been increasingly used for several surgeries including adrenalectomy. Single incision robotic adrenalectomy (SIRA) aims to combine the merits of robotic surgery with previously defined single incision laparoscopic techniques. It has been shown to be safe and feasible, however, there are only few studies on this new technique. Due to scant data on SIRA in the current literature, it remains to be a current challenge in adrenal surgery. In this review, our goal is to present current literature on SIRA and discuss the data regarding perioperative outcomes, patient selection, learning curve, and its limitations.