Researcher:
Darçın, Kamil

Profile Picture
ORCID

Job Title

Doctor

First Name

Kamil

Last Name

Darçın

Name

Name Variants

Darçın, Kamil

Email Address

Birth Date

Filters

2023 - 20246

Advanced Search

Filter by

Settings

Researcher Of Publications: search.filters.isAuthorOfPublication.cd2841d4-1e47-4672-b604-1b1fad446c24

Search Results

Now showing 1 - 6 of 6
  • Placeholder
    PublicationMetadata only
    Pushing the boundaries: circumferential endoscopic submucosal dissection in distal duodenum
    (Elsevier Inc., 2024) Aslan, Fatih; Taşkın, Orhun Çığ; Tellioğlu, Gürkan; Karakaya, Afak Durur; Özer, Serhat; Darçın, Kamil; School of Medicine; Koç University Hospital
  • Placeholder
    PublicationMetadata only
    Visual evaluation of plethysmographic waveforms: introducing the simple systolic ratio as an indicator of fluid responsiveness
    (Galenos Publishing House, 2024) Karakaya, Muhammet Ahmet; N/A; Söğüt, Muhammet Selman; Darçın, Kamil; Manici, Mete; Gürkan, Yavuz; School of Medicine; Koç University Hospital
    Objective: For patient safety, maintaining hemodynamic stability during surgical procedures is critical. Dynamic indices [such as systolic pressure variation (SPV) and pulse pressure variation (PPV)], have recently seen an increase in use. Given the risks associated with such invasive techniques, there is growing interest in non-invasive monitoring methods-and plethysmographic waveform analysis. However, many such non-invasive methods involve intricate calculations or brand-specific monitors. This study introduces the simple systolic ratio (SSR), derived from pulse oximetry tracings, as a non-invasive method to assess fluid responsiveness. Methods: This prospective observational study included 25 adult patients whose SPV, PPV, and SSR values were collected at 30-min intervals during open abdominal surgery. The SSR was defined as the ratio of the tallest waveform to the shortest waveform within pulse tracings. The correlations among SSR, SPV, and PPV were analyzed. Additionally, anaesthesia specialists visually assessed pulse oximetry tracings to determine fluid responsiveness using the SSR method. Results: Strong correlations were observed between SSR and both SPV (r = 0.715, P < 0.001) and PPV (r = 0.702, P < 0.001). Receiver operator curve analysis identified optimal SSR thresholds for predicting fluid responsiveness at 1.47 for SPV and 1.50 for PPV. A survey of anaesthesia specialists using the SSR method to visually assess fluid responsiveness produced an accuracy rate of 83%. Conclusion: Based on the strong correlations it exhibits with traditional markers, SSR has great potential as a clinical tool, especially in resource-limited settings. However, further research is needed to establish its role, especially as it pertains to its universal applicability across monitoring devices. © 2024 by the Turkish Anesthesiology and Reanimation Association/Turkish Journal of Anaesthesiology & Reanimation is published by Galenos Publishing House.
  • Placeholder
    PublicationMetadata only
    Effects of erector spinae plane block on opioid consumption in patients undergoing hand-assisted laparoscopic donor nephrectomy: a randomized controlled trial
    (Edizioni Minerva Medica, 2024) Karakaya, Muhammet A.; Yenigun, Yilmaz; Özkalaycı, Özlem; Çetin, Seçil; Darçın, Kamil; Akyollu, Başak; Arpalı, Emre; Koçak, Burak; Gürkan, Yavuz; School of Medicine; Koç University Hospital
    Background: The erector spinae plane block is a relatively new regional anesthesia technique that is expected to provide some benefits for postoperative analgesia. This study investigated the effects of erector spinae plane block on postoperative opioid consumption in kidney donors undergoing hand-assisted laparoscopic donor nephrectomy for renal transplantation. Methods: Fifty-two donors scheduled for elective hand-assisted laparoscopic donor nephrectomy were randomly divided into the block (25 donors) and control (27 donors) groups. Donors in the block group received 30 mL of 0.25% bupivacaine under ultrasound guidance, whereas the control group received no block treatment. The primary outcome measure was the amount of fentanyl administered via patient-controlled analgesia at 24 h. Secondary outcomes included the duration of stay, opioid consumption in the post-anesthesia care unit, and pain scores during the recording hours. Results: No significant differences were observed between the groups regarding total opioid consumption converted to intravenous morphine equivalent administered via patient-controlled analgesia (33.3 +/- 21.4 mg vs. 37.5 +/- 18.5 mg; P=0.27) and in the postanesthesia care unit (1.5 +/- 0.9 mg vs. 1.4 +/- 0.8 mg; P=0.55). The duration of stay in the postanesthesia care unit (86.3 +/- 32.6 min vs. 85.7 +/- 33.6 min; P=0.87) was similar between the groups. There was no significant difference between the groups in the postoperative donor-reported NRS pain scores (P>0.05 for all the time points). Conclusions: Preoperative erector spinae plane block is not an effective strategy for reducing postoperative pain or opioid consumption in patients undergoing hand-assisted laparoscopic donor nephrectomy. Different block combinations are needed for optimal pain management in hand-assisted laparoscopic donor nephrectomy.
  • Placeholder
    PublicationMetadata only
    Does nociception level index-guided opioid administration reduce intraoperative opioid consumption? a systematic review and meta-analysis
    (Lippincott Williams and Wilkins, 2024) Karakaya, Muhammet Ahmet; Söğüt, Muhammet Selman; Kalyoncu, İlayda; Manici, Mete; Darçın, Kamil; School of Medicine; Koç University Hospital
    Background: The nociception level (NOL) index is a quantitative parameter derived from physiological signals to measure intraoperative nociception. The aim of this systematic review and meta-analysis was to evaluate if NOL monitoring reduces intraoperative opioid use compared to conventional therapy (opioid administered at clinician discretion). METHODS: This meta-analysis comprises randomized clinical trials comparing NOL-guided opioid administration to conventional therapy in adult patients undergoing any type of surgery. A systematic search of PubMed, Scopus, and CENTRAL databases was conducted. The primary outcome was intraoperative opioid consumption and the effect estimate of the NOL index was measured using the standardized mean difference (SMD) where 0.20 is considered a small and 0.80 a large effect size. A random-effects model with Hartung-Knapp-Sidik-Jonkman adjustment was applied to estimate the treatment effect. Heterogeneity was explored clinically and statistically (using the inconsistency I2; statistic, prediction intervals, and influence analysis). The quality (certainty) of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) guidelines methodology. RESULTS: This review comprised 9 trials (519 patients). The intraoperative opioid SMD (NOL monitoring versus conventional therapy) was -0.26 (95% confidence interval [CI], -0.82 to 0.30; P =.31; low certainty of evidence). We observed substantial clinical (intraoperative opioid regimens) and statistical heterogeneity with the I2; statistic being 86% (95% CI, 75%-92%). The prediction interval was between -1.95 and 1.42 indicating where the SMD between NOL and conventional therapy would lie if a similar study were conducted in the future. CONCLUSIONS: This meta-analysis does not provide evidence supporting the role of NOL monitoring in reducing intraoperative opioid consumption. Copyright © 2024 International Anesthesia Research Society.
  • Placeholder
    PublicationMetadata only
    Suprainguinal fascia iliaca block for distal femur tumor surgery
    (Kare Publishing, 2023) Gürkan, Yavuz; Gedik, Cemil Cihad; Darçın, Kamil; Manici, Mete; School of Medicine; Koç University Hospital
  • Placeholder
    PublicationMetadata only
    Selective dorsal scapular nerve and long thoracic nerve blocks for rescue analgesia in scapulothoracic arthrodesis surgery: a case report
    (Lippincott Williams & Wilkins, 2024) Gürkan, Yavuz; Şimşek, Doğa; Güllü, Buğra; Manici, Mete; Darçın, Kamil; Yürük, Batuhan; Demirhan, Mehmet; Eren, İlker; School of Medicine; Koç University Hospital
    Scapulothoracic arthrodesis (STA) surgery is performed to stabilize the scapula in patients with facioscapulohumeral dystrophy (FSHD). Postoperative pain could be a major problem even while using erector spinae plane block (ESPB). We performed a preoperative ESPB with an intraoperative ESPB catheter, but rescue analgesia was needed for pain in the periscapular area in the postoperative period. The patient's pain score was reduced by applying an ultrasound-guided dorsal scapular nerve (DSN) and long thoracic nerve (LTN) block. Selective DSN and LTN blocks can be effective in enhancing postoperative analgesia in STA surgery.