Researcher:
Kanmaz, Turan

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Faculty Member

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Turan

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Kanmaz

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Kanmaz, Turan

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2019 - 201912020 - 202322

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Researcher Of Publications: search.filters.isAuthorOfPublication.dc6b054c-3a8f-4457-bc84-575d75d4885c

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Now showing 1 - 10 of 23
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    Patient with hemophilia a undergoing consecutive coronary bypass and live donor liver transplantation: a case report
    (Elsevier Science Inc, 2021) N/A; N/A; Karataş, Cihan; Alim, Altan; Tırnova, İsmail; Demir, Barış; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 275800
    Liver transplantation surgery due to cirrhosis in patients with hemophilia is rare and there are limited cases in the literature. We present a case of a patient with hemophilia A who underwent 2 consecutive surgeries owing to coronary artery disease and cryptogenic cirrhosis with hepatocel-lular carcinoma. After these surgeries, no bleeding or other complications were seen, and the fac-tor VIII levels have not changed since liver transplantation in the follow-up.
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    P-139 the effects of the incision type on incisional hernia results of living donor liver transplant; single center experience
    (Oxford University Press (OUP), 2022) Tırnova, İsmail; N/A; N/A; Kanmaz, Turan; N/A; Faculty Member; N/A; School of Medicine; Koç University Hospital; N/A; 275799
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    Does really, "age" matter?
    (Lippincott Williams & Wilkins, 2022) Hoş, Gültekin; N/A; Karataş, Cihan; Alim, Altan; Kanmaz, Turan; Doctor; Doctor; Faculty Member; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; 275799
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    First laparoscopic donor hepatectomy cases of Turkey
    (Wiley, 2019) N/A; N/A; Karataş, Cihan; Alper, Aydın; Mecit, Nesimi; Kalayoğlu, Münci; Kanmaz, Turan; Doctor; Faculty Member; Doctor; Doctor; Faculty Member; N/A; School of Medicine; N/A; N/A; School of Medicine; Koç University Hospital; N/A; Koç University Hospital; Koç University Hospital; N/A; N/A; 119809; N/A; N/A; 275799
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    Hepatic artery intimal dissection during living donor liver transplantation: a new modified approach
    (Elsevier Inc., 2023) Karataş, Cihan; Alim, Altan; Tırnova, İsmail; Demir, Barış; Akbulut, Akın; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 275799
    Ensuring optimal arterial flow in solid organ transplantation is very important. Insufficient flow causes important problems such as bile duct problems, intrahepatic abscess formation, and organ loss. Arterial intimal dissection is an important factor that negatively affects organ blood flow. In this study, hepatic artery dissections that we detected in patients who underwent living donor liver transplantation in our clinic were defined, and the microvascular intima-adventitial fixation technique, which can be considered a new approach, was described.
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    Association of graft to recipient weight ratio and outcomes of living and split donor liver transplantation in pediatric less than 20 kg
    (Wiley, 2021) N/A; N/A; N/A; N/A; N/A; N/A; Andaçoğlu, Oya Münevver; Karataş, Cihan; Baygül, Arzu Eden; Mecit, Nesimi; Kanmaz, Turan; Kalayoğlu, Münci; Doctor; Doctor; Faculty Member; Doctor; Faculty Member; Doctor; Koç University Hospital; N/A; N/A; 272290; N/A; 275799; N/A
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    Split liver transplant from deceased marginal donor: a case report
    (Elsevier Science Inc, 2022) N/A; N/A; Karataş, Cihan; Alim, Altan; Yıldırımoğlu, Turan; Tırnova, İsmail; Demir, Barış; Akbulut, Akın; Kanmaz, Turan; Doctor: Doctor; Other; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 275800
    The relative paucity of deceased donor organs and the progressive increase in patients with cirrhosis have led transplant centers to consider organs from marginal donors (elderly donors, prolonged stay in the intensive care unit (ICU), liver steatosis-steatotic grafts, severe hypernatremia, and use of inotropes). Recently, the use of those marginal grafts has increased, but splitting liver is still debatable.Herein, we present a 28-year-old deceased donor who had a history of traumatic brain injury. The patient stayed in ICU for 3 days with high sodium level (188 mEq/L) and was hemodynamically supported with single inotrope. At the time of procurement, core biopsies were taken from the right lobe and left lateral segment of the liver, with results demonstrating 5% necrosis. A decision was made for split liver transplant as left lateral sector and extended right lobe.Liver graft was divided into a left lateral segment to be transplanted to a 4-year-old child with secondary biliary cirrhosis due to previous liver transplant and a right extended liver lobe for an adult patient with hepatocellular carcinoma waiting 10 months on the waiting list. Both liver transplants were performed uneventfully. Patients were discharged on the 11th and 56th days after transplant. The liver function tests remained normal during the follow up period of 2 years. A marginal graft with more than one risk factor should not be discarded liberally. Splitting such grafts could be considered in a highly selective recipients.
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    Using O-Arm (TM) cholangiography in living donor liver transplantation
    (Lippincott Williams & Wilkins, 2022) Hoş, Gültekin; N/A; Karataş, Cihan; Alim, Altan; Yalçın, Ali Bektaş; Demir, Barış; Tırnova, İsmail; Akbulut, Akın; Alper, Aydın; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; Faculty Member; N/A; N/A; N/A; N/A; N/A; N/A; School of Medicine; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 119809; 275799
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    Examining the hepatic immune system in children with liver disease with fine needle aspiration
    (Lippincott Williams & Wilkins, 2022) N/A; N/A; N/A; N/A; N/A; N/A; N/A; Yüksel, Muhammed; Demirbaş, Burak; Mizikoğlu, Özlem; Tütüncü, Yıldız; Kanmaz, Turan; Oğuzkurt, Levent; Arıkan, Çiğdem; Researcher; Doctor; Researcher; Faculty Member; Faculty Member; Faculty Member; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); N/A; N/A; N/A; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; 239430; 275799; 13559; 240198
    Objectives: Liver biopsy is the standard in diagnosing liver diseases. Yet, it provides little space to perform comprehensive immune profiling of the liver. Hence, we explored whether fine needle aspirates (FNAs) could be used to elucidate the hepatic immunity in children. Methods: We enrolled 74 children undergoing diagnostic (n = 17) or protocol biopsy (n = 57) following liver transplantation (LT). Matched blood and FNAs were obtained. Additionally, explant liver tissue was collected from children (n = 14) undergoing LT. Immune cells were isolated from peripheral blood, FNAs and explanted livers. Immune-phenotypical profiling was done by flow cytometry. Results: Biopsied patients (58% female) were at a median age of 46 months (interquartile range [IQR]: 12–118) and LT patients (71% female) were 48 months (IQR: 21–134, P = 0.78) old. CD69+, a hallmark of tissue-resident immune cells was expressed in 1.3% of CD3+ T cells from blood being higher in FNA (20%) and tissue (49%, P < 0.001). CD4+ T-cell frequencies in tissue (13%) and FNAs (20%) were lower compared to blood (35%, P < 0.001) whereas CD8+ T cells in tissue (33.5%) and FNA (32%) were higher than in blood (25%, P < 0.01). Mucosal associated invariant T cells were enriched in liver tissue (8.8%) and in the FNA (4.4%) compared to blood (1.7%, P < 0.001). Whereas the percentage of total Tregs (CD4+CD25+FOXP3+CD127low/−) decreased, the proportion of activated Tregs (CD4+CD45RA-FOXP3high) increased in FNA and explant. Breg (CD19+CD20+CD24highCD38high) frequencies were similar in all groups. Conclusion: FNA is a practical method to sample the liver immune system collecting even small cell subsets such as regulatory T/B cells.
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    Urgent liver transplantation from deceased donor with a calcified hydatid cyst: a case report
    (Elsevier Science Inc, 2022) N/A; N/A; Karataş, Cihan; Alim, Altan; Tırnova, İsmail; Akbulut, Akın; Demir, Barış; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; 275799
    Liver transplantation is the final treatment option for end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The large gap between the growing list of patients awaiting liver transplantation and the scarcity of donor organs has fueled efforts to maximize the existing donor pool and identify new avenues. We treated a 13-year-old boy who had acute liver failure, due to Wilson's disease, with transplantation of a liver from a deceased liver donor with a calcified hydatid cyst. After 3 years of follow-up, liver function tests remained normal, hydatid cyst serology was negative, and no hydatid cyst or other problems were observed.