Researcher:
Esencan, Ecem

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Undergraduate Student

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Ecem

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Esencan

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Esencan, Ecem

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Now showing 1 - 4 of 4
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    Publication
    A risk assessment comparison of breast cancer and factors affected to risk perception of women in Turkey: a cross-sectional study
    (Iranian Journal of Public Health, 2017) Yüksel, Serpil; Altun Uğraş, Gülay; Çavdar, İkbal; Bozdoğan, Atilla; Özkan Gürdal, Sibel; Akyolcu, Neriman; Varol Saraçoğlu, Gamze; Özmen, Vahit; N/A; Esencan, Ecem; Undergraduate Student; School of Medicine; Koç University Hospital; N/A
    Background: The increase in breast cancer incidence has enhanced attention towards breast cancer risk. The aim of this study was to determine the risk of breast cancer and risk perception of women, factors that affect risk perception, and to determine differences between absolute risk and the perception of risk. Methods: This cross-sectional study was carried out among 346 women whose score in the Gail Risk Model (GRM) was ≥ 1.67% and/or had a 1st degree relative with breast cancer in Bahçeşehir town in Istanbul, Turkey between Jul 2012 and Dec 2012. Data were collected through face-to-face interviews. The level of risk for breast cancer has been calculated using GRM and the Breast Cancer Risk Assessment Form (BCRAF). Breast cancer risk perception (BCRP), has been evaluated by visual analogue 100-cm-long scale. Results: Even though 39.6% of the women considered themselves as high-risk carriers, according to the GRM and the BCRAF, only 11.6% and 9.8% of women were in the “high risk” category, respectively. There was a positive significant correlation between the GRM and the BCRAF scores (P<0.001), and the BCRAF and BCRP scores (P<0.001). Factors related to high-risk perception were age (40-59 yr), post-menopausal phase, high-very high economic income level, existence of breast cancer in the family, having regular breast self-examination and clinical breast examination (P<0.05). Conclusion: In women with high risk of breast, cancer there is a significant difference between the women’s risk perception and their absolute risk level.
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    Publication
    XENON in medical area: emphasis on neuroprotection in hypoxia and anesthesia
    (Wolters Kluwer Medknow Publications, 2013) Robinot, Alexander; Zhang, John H.; N/A; Esencan, Ecem; Yüksel, Simge; Tosun, Yusuf Berk; Solaroğlu, İhsan; Undergraduate Student; Undergraduated Student; Undergraduated Student; Faculty Member; School of Medicine; School of Medicine; School of Medicine; School of Medicine; Koç University Hospital; N/A; N/A; N/A; 102059
    Xenon is a medical gas capable of establishing neuroprotection, inducing anesthesia as well as serving in modern laser technology and nuclear medicine as a contrast agent. In spite of its high cost, its lack of side effects, safe cardiovascular and organoprotective profile and effective neuroprotective role after hypoxic-ischemic injury (HI) favor its applications in clinics. Xenon performs its anesthetic and neuroprotective functions through binding to glycine site of glutamatergic N-methyl-D-aspartate (NMDA) receptor competitively and blocking it. This blockage inhibits the overstimulation of NMDA receptors, thus preventing their following downstream calcium accumulating cascades. Xenon is also used in combination therapies together with hypothermia or sevoflurane. The neuroprotective effects of xenon and hypothermia cooperate synergistically whether they are applied synchronously or asynchronously. Distinguishing properties of Xenon promise for innovations in medical gas field once further studies are fulfilled and Xenon's high cost is overcome.
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    PublicationOpen Access
    A risk assessment comparison of breast cancer and factors affected to risk perception of women in Turkey: a cross-sectional study
    (Tehran University of Medical Sciences, 2017) Yüksel, Serpil; Uğraş, Gülay Altun; Çavdar, İkbal; Bozdoğan, Atilla; Gürdal, Sibel Özkan; Akyolcu, Neriman; Saraçoğlu, Gamze Varol; Özmen, Vahit; Esencan, Ecem; School of Medicine
    Background: The increase in breast cancer incidence has enhanced attention towards breast cancer risk. The aim of this study was to determine the risk of breast cancer and risk perception of women, factors that affect risk perception, and to determine differences between absolute risk and the perception of risk. Methods: This cross-sectional study was carried out among 346 women whose score in the Gail Risk Model (GRM) was >= 1.67% and/or had a 1(st) degree relative with breast cancer in Bahçeşehir town in Istanbul, Turkey between Jul 2012 and Dec 2012. Data were collected through face-to-face interviews. The level of risk for breast cancer has been calculated using GRM and the Breast Cancer Risk Assessment Form (BCRAF). Breast cancer risk perception (BCRP), has been evaluated by visual analogue 100-cm-long scale. Results: Even though 39.6% of the women considered themselves as high-risk carriers, according to the GRM and the BCRAF, only 11.6% and 9.8% of women were in the "high risk" category, respectively. There was a positive significant correlation between the GRM and the BCRAF scores (P<0.001), and the BCRAF and BCRP scores (P<0.001). Factors related to high-risk perception were age (40-59 yr), post-menopausal phase, high-very high economic income level, existence of breast cancer in the family, having regular breast self-examination and clinical breast examination (P<0.05). Conclusion: In women with high risk of breast, cancer there is a significant difference between the women's risk perception and their absolute risk level. Screen reader support enabled.
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    PublicationOpen Access
    Thyroid hormone levels in late preterm, early term and term infants: a study with healthy neonates revealing reference values and factors affecting thyroid hormones
    (De Gruyter, 2017) Erçin, Seçil; Gürsoy, Tuğba; Aktaş, Özge Nur; Soysal, Elif; Esencan, Ecem; Faculty Member; Resercher; School of Medicine; Koç University Hospital; 214691; N/A; N/A; N/A
    Background: Thyroid function tests in neonates have been challenging to interpret because their levels are affected by several neonatal and delivery-related factors. The aim of the study was to evaluate reference values of thyroxine (T4) and thyrotropin (TSH) levels in different gestational age groups and to demonstrate the affect of perinatal factors on thyroid hormones. Methods: Medical records of 7616 neonates whose gestational age ranges between 34 and 42 weeks were analyzed retrospectively. Gender, mode of delivery, gestational age, postnatal age and birth weight were noted together with TSH and T4 levels. Results: Gestational age (r = 0.14, p < 0.001) and birth weight (r = 0.12, p < 0.001) had positive correlation with T4 levels, whereas they had no effect on TSH levels. Males had higher TSH and lower T4 levels (p = 0.001 for both) compared with females. T4 levels of babies born via vaginal delivery were lower than the ones born via cesarean section (p = 0.01). Multivariable analysis yielded gestational age as the only factor affecting T4 levels (p < 0.001). T4 and TSH levels based on 2.5-97.5 percentile cutoffs according to gestational age were presented. Conclusions: The thyroid hormone ranges given in this study can help pediatricians to interpret the thyroid hormone results with ease.