Researcher:
Tırnova, İsmail

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Doctor

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İsmail

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Tırnova

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Tırnova, İsmail

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2021 - 20237

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Researcher Of Publications: search.filters.isAuthorOfPublication.eecbba60-72fe-4f3f-add3-21c21d857a9e

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    Patient with hemophilia a undergoing consecutive coronary bypass and live donor liver transplantation: a case report
    (Elsevier Science Inc, 2021) N/A; N/A; Karataş, Cihan; Alim, Altan; Tırnova, İsmail; Demir, Barış; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 275800
    Liver transplantation surgery due to cirrhosis in patients with hemophilia is rare and there are limited cases in the literature. We present a case of a patient with hemophilia A who underwent 2 consecutive surgeries owing to coronary artery disease and cryptogenic cirrhosis with hepatocel-lular carcinoma. After these surgeries, no bleeding or other complications were seen, and the fac-tor VIII levels have not changed since liver transplantation in the follow-up.
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    Hepatic artery intimal dissection during living donor liver transplantation: a new modified approach
    (Elsevier Inc., 2023) Karataş, Cihan; Alim, Altan; Tırnova, İsmail; Demir, Barış; Akbulut, Akın; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 275799
    Ensuring optimal arterial flow in solid organ transplantation is very important. Insufficient flow causes important problems such as bile duct problems, intrahepatic abscess formation, and organ loss. Arterial intimal dissection is an important factor that negatively affects organ blood flow. In this study, hepatic artery dissections that we detected in patients who underwent living donor liver transplantation in our clinic were defined, and the microvascular intima-adventitial fixation technique, which can be considered a new approach, was described.
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    Split liver transplant from deceased marginal donor: a case report
    (Elsevier Science Inc, 2022) N/A; N/A; Karataş, Cihan; Alim, Altan; Yıldırımoğlu, Turan; Tırnova, İsmail; Demir, Barış; Akbulut, Akın; Kanmaz, Turan; Doctor: Doctor; Other; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 275800
    The relative paucity of deceased donor organs and the progressive increase in patients with cirrhosis have led transplant centers to consider organs from marginal donors (elderly donors, prolonged stay in the intensive care unit (ICU), liver steatosis-steatotic grafts, severe hypernatremia, and use of inotropes). Recently, the use of those marginal grafts has increased, but splitting liver is still debatable.Herein, we present a 28-year-old deceased donor who had a history of traumatic brain injury. The patient stayed in ICU for 3 days with high sodium level (188 mEq/L) and was hemodynamically supported with single inotrope. At the time of procurement, core biopsies were taken from the right lobe and left lateral segment of the liver, with results demonstrating 5% necrosis. A decision was made for split liver transplant as left lateral sector and extended right lobe.Liver graft was divided into a left lateral segment to be transplanted to a 4-year-old child with secondary biliary cirrhosis due to previous liver transplant and a right extended liver lobe for an adult patient with hepatocellular carcinoma waiting 10 months on the waiting list. Both liver transplants were performed uneventfully. Patients were discharged on the 11th and 56th days after transplant. The liver function tests remained normal during the follow up period of 2 years. A marginal graft with more than one risk factor should not be discarded liberally. Splitting such grafts could be considered in a highly selective recipients.
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    Using O-Arm (TM) cholangiography in living donor liver transplantation
    (Lippincott Williams & Wilkins, 2022) Hoş, Gültekin; N/A; Karataş, Cihan; Alim, Altan; Yalçın, Ali Bektaş; Demir, Barış; Tırnova, İsmail; Akbulut, Akın; Alper, Aydın; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; Faculty Member; N/A; N/A; N/A; N/A; N/A; N/A; School of Medicine; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; N/A; N/A; 119809; 275799
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    Urgent liver transplantation from deceased donor with a calcified hydatid cyst: a case report
    (Elsevier Science Inc, 2022) N/A; N/A; Karataş, Cihan; Alim, Altan; Tırnova, İsmail; Akbulut, Akın; Demir, Barış; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; N/A; 275799
    Liver transplantation is the final treatment option for end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The large gap between the growing list of patients awaiting liver transplantation and the scarcity of donor organs has fueled efforts to maximize the existing donor pool and identify new avenues. We treated a 13-year-old boy who had acute liver failure, due to Wilson's disease, with transplantation of a liver from a deceased liver donor with a calcified hydatid cyst. After 3 years of follow-up, liver function tests remained normal, hydatid cyst serology was negative, and no hydatid cyst or other problems were observed.
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    Liver transplantation for congenital metabolic disorders
    (İstanbul Üniversitesi, 2022) N/A; N/A; N/A; N/A; N/A; N/A; Alim, Altan; Tırnova, İsmail; Karataş, Cihan; Akbulut, Akın; Demir, Barış; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 275799
    Objective: The aim of the study is to identify the indications for and the outcomes of liver transplantation in congenital metabolic diseases. Methods: Indications, survival, and complications of liver transplantation performed between July 2018 and September 2021 for congenital metabolic diseases were examined. Demographic information of patients, liver graft types, and donor information were included in the analysis. Results: A total of 23 liver transplants were performed in 22 patients with a mean age of 7.3 ± 9.3 and a mean weight of 23.6 ± 21.7. The types and frequencies of liver grafts used for transplantation in this analysis include 18 left lateral sectors, 1 left lobe, 3 right lobes, and 1 deceased full-size liver. Two of the left lateral sectors were retrieved from deceased split liver grafts. Mortality was observed in 2 patients (9%), 1 in the early and the second in the late postoperative period. Excluding the 2 fatalities, 3 patients required reoperation due to issues with blood flow through the portal vein. Due to hepatic artery thrombosis, 1 patient required stent placement. Biliary tract complications developed in 5 (22%) patients with dilatation and stenting being performed by interventional radiology. The surviving patients (91%) had an uneventful postoperative course after discharge from the hospital.  Conclusion: Liver transplantation is increasingly used either as a definitive treatment method or to improve the course of the disease for metabolic diseases. With the high survival rates, reduction in the frequency of attacks, improved effects on growth, development, and nutrition, it is clear that liver transplantation is a valuable tool for use in congenital metabolic disorders. Examining appropriate patient selection and ideal timing for transplantation remain important issues for further examination.
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    Using pericholedochal varix inflow for complete portal vein thrombosis in living donor liver transplantation: a case report
    (Elsevier Science Inc, 2022) N/A; N/A; N/A; N/A; N/A; Tırnova, İsmail; Karataş, Cihan; Mecit, Nesimi; Kanmaz, Turan; Kalayoğlu, Münci; Doctor; Doctor; Doctor; Faculty Member; Doctor; N/A; N/A; N/A; School of Medicine; N/A; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; 275799; N/A
    One of the crucial steps of liver transplantation is to provide the portal inflow. Portal vein throm-bosis is the most challenging factor to achieve. Using a pericholedochal varix for portal inflow in a patient with complete portal vein thrombosis in living donor liver transplantation (LDLT) is a rare technique. We present our experience of a LDLT with PVT.